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Neostigmine

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Identification
Molecular formula
C12H19N2O2
CAS number
59-99-4
IUPAC name
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium
State
State

At room temperature, Neostigmine is typically in a solid state, existing as a crystalline powder.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.00
Boiling point (Celsius)
351.00
Boiling point (Kelvin)
624.00
General information
Molecular weight
223.30g/mol
Molar mass
223.3100g/mol
Density
1.4000g/cm3
Appearence

Neostigmine appears as a white crystalline powder. It is highly soluble in water and generally forms clear solutions.

Comment on solubility

Solubility of [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium

The solubility of the compound [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium, with the molecular formula C12H19N2O2, can be quite interesting due to its unique structural features. In general, the solubility of a compound can depend on several factors, including polarity, molecular size, and the presence of functional groups. Here are some key aspects to consider:

  • Polarity: The presence of the dimethylcarbamoyloxy group and the ammonium ion suggest that this compound is likely polar, which may enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of this compound to form hydrogen bonds, due to the hydroxyl and nitrogen functionalities, may also contribute to its solubility.
  • Molecular Size: With a molecular weight of 225.30 g/mol, the size of the compound may influence its ability to dissolve compared to smaller organic molecules.
  • Solvent Interaction: Solubility may vary greatly depending on the solvent used. While it might dissolve readily in polar solvents, it might have limited solubility in non-polar environments.

As a general rule, "like dissolves like." Thus, the ability of [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium to dissolve will be affected by the nature of the solvent it encounters. For practical applications, it would be beneficial to conduct specific solubility testing in different solvent environments to better understand its behavior.

Interesting facts

Interesting Facts about [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium

[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium is an intriguing chemical compound that belongs to the class of quaternary ammonium salts. This compound has garnered attention in various fields, including pharmaceuticals, agriculture, and chemical biology. Here are some fascinating aspects of this compound:

  • Structure and Functionality: The presence of the dimethylcarbamoyloxy functional group paired with a phenyl ring provides this compound with unique chemical properties. The quaternary ammonium component enhances its ability to interact with biological systems, making it a potential candidate for drug delivery.
  • Biological Applications: Quaternary ammonium compounds, like this one, often exhibit antimicrobial properties. They can be utilized in antiseptic formulations, contributing to hygiene and infection control.
  • Industrial Use: Due to its surfactant properties, this compound may be employed in cleaning agents and fabric softeners, effectively reducing surface tension and enhancing cleaning efficiency.
  • Research Potential: The compound is a subject of ongoing research investigating its efficacy in formulations for targeted therapy. Its compatibility with other compounds also sparks interest in developing novel therapeutic agents.

As a scientist studying compounds like [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium, one can appreciate how minor structural variations can lead to significant changes in the behavior and application of a compound. The versatility of such compounds opens new avenues in both scientific research and industrial applications. This emphasizes the profound relationship between structure and function in the chemical world.

Synonyms
NEOSTIGMINE
Eustigmin
Eustigmine
Vagostigmine
Prostigmine
59-99-4
Prostigmin
Juvastigmin
Neostigmin
Neostigminum
Intrastigmina
m-Trimethylammoniumphenyldimethylcarbamate
3-Trimethylammoniumphenyl N,N-dimethylcarbamate
Neostigmine [BAN]
Neostigmine ion
Neostigmine cation
CCRIS 3079
Neostigmine (cation)
HSDB 3921
(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate
3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium
Neostigmine (BAN)
UNII-3982TWQ96G
[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
BRN 3615946
CHEBI:7514
Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-
3982TWQ96G
Prostigmin (TN)
(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate (ester)
Ammonium, (m-hydroxyphenyl)trimethyl-, dimethylcarbamate (ester)
CHEMBL278020
DTXSID1023360
Prozerin
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium bromide
3-{[(dimethylamino)carbonyl]oxy}-N,N,N-trimethylanilinium
NEOSTIGMINE (MART.)
NEOSTIGMINE [MART.]
3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium
Benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfonatooxymethane
NCGC00163240-01
3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylanilinium
CAS-114-80-7
Neostigmina
Spectrum_001061
NEOSTIGMINE [MI]
Prestwick0_000468
Prestwick1_000468
Prestwick2_000468
Prestwick3_000468
Spectrum2_001278
Spectrum4_000072
Spectrum5_001234
Lopac-N-2001
NEOSTIGMINE [HSDB]
bmse000762
NEOSTIGMINE [VANDF]
Lopac0_000816
SCHEMBL34419
BSPBio_000576
KBioGR_000623
KBioSS_001541
DivK1c_000165
DivK1c_000198
SPBio_001276
SPBio_002515
BPBio1_000634
DTXCID703360
GTPL8993
ALWKGYPQUAPLQC-UHFFFAOYSA-
KBio1_000165
KBio1_000198
KBio2_001541
KBio2_004109
KBio2_006677
NINDS_000165
NINDS_000198
HMS2089A22
BDBM50022775
STL058953
AKOS005711366
CCG-204900
DB01400
IDI1_000165
IDI1_000198
MLS-0002855
NCGC00015730-01
NCGC00015730-02
NCGC00015730-03
NCGC00015730-04
NCGC00015730-05
NCGC00015730-06
NCGC00015730-07
NCGC00015730-08
NCGC00015730-09
NCGC00015730-24
NCGC00021658-03
SBI-0050793.P004
AB00053807
NS00001580
C07258
D08261
AB00053807-25
AB00053807-26
AB00053807_27
AB00053807_28
AB00053807_29
Q410546
BRD-K18922609-004-04-1
BRD-K18922609-004-14-0
BRD-K18922609-004-22-3
BRD-K18922609-004-23-1
BRD-K18922609-004-24-9
InChI=1/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1