Benzocaine | Solubility of Things

Identification

Molecular formula

C₉H₁₁NO₂

CAS number

94-09-7

IUPAC name

3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide

State

At room temperature, Benzocaine is in a solid state, typically existing as a white powder. Being a local anesthetic compound, it is usually utilized in medicinal formulations.

Melting point (Celsius)

92.00

Melting point (Kelvin)

365.15

Boiling point (Celsius)

310.00

Boiling point (Kelvin)

583.15

General information

Molecular weight

165.19g/mol

Molar mass

165.1900g/mol

Density

1.1860g/cm³

Appearence

Benzocaine is a white granule or crystal powder that is odorless. It is commonly used in its powdered form, but in some preparations, it might appear as part of a cream or gel formulation due to its application in topical anesthetics.

Comment on solubility

Solubility of 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide

The solubility of the compound 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide, with the chemical formula C₉H₁₁NO₂, is influenced by several factors, including its structural features and interactions with solvents.

Key Factors Affecting Solubility:

Molecular Structure: The presence of the dimethylamino group can enhance solubility in polar solvents due to its ability to form hydrogen bonds.
Hydroxy Group: The hydroxybenzoyl moiety contributes to increased solubility in many organic solvents, benefiting from hydrogen bonding capabilities.
Size and Polarity: Linear compounds with lower molecular weights generally exhibit higher solubility compared to larger, more rigid compounds.

In practical terms, the solubility of this compound can vary significantly between polar and non-polar solvents. It is often the case that:

It shows better solubility in water due to the presence of polar functional groups.
It may exhibit lower solubility in non-polar solvents such as hexane.

Understanding these solubility characteristics is crucial for applications in drug formulation and chemical synthesis, where solvent selection plays a significant role in the efficiency of processes.

Interesting facts

Interesting Facts about 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide

This compound, often referred to in various scientific contexts, plays a significant role in biochemical research and pharmaceuticals. Here are some intriguing aspects of this complex molecule:

The Dual Functionality: This compound exhibits both amino and hydroxyl functionalities, making it an interesting candidate for studying interactions in biological systems.
Enhanced Solubility: The presence of the dimethylamino group contributes to its solubility profile, which is crucial for its bioavailability in pharmacological applications.
Research Applications: Compounds like this are often investigated for their potential use in therapies related to cancer, as they can inhibit specific enzymes or receptors involved in tumor growth.
Molecular Diversity: The intricate design of this compound allows chemists to modify its structure, enhancing its effectiveness while tuning its properties for different experimental needs.
Structure-Activity Relationship (SAR): Understanding how changes in its structure affect its biological activity is a central theme in medicinal chemistry, making this compound an essential subject of study.

In conclusion, the investigation of 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide offers not only insights into the chemical behavior of similar molecules but also opens potential pathways for the development of effective drug candidates. As chemists continue to explore its properties, this compound will remain a captivating topic in the world of chemical sciences.

Synonyms

208260-29-1

ZM 336372

ZM336372

ZM-336372

3-(dimethylamino)-N-(3-(4-hydroxybenzamido)-4-methylphenyl)benzamide

N-[5-(3-Dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide

Benzamide, 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]-

CHEMBL186526

n-(5-(3-dimethylaminobenzamido)-2-methylphenyl)-4-hydroxybenzamide

3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide

3-(dimethylamino)-N-[3-(4-hydroxybenzamido)-4-methylphenyl]benzamide

3-(Dimethylamino)- N -[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide

N-{5-[3-(DIMETHYLAMINO)BENZAMIDO]-2-METHYLPHENYL}-4-HYDROXYBENZAMIDE

Bio1_001346

MFCD02683971

compound 1 [PMID: 15454231]

BiomolKI_000053

BiomolKI2_000059

BMK1-F5

BSPBio_001240

KBioGR_000580

KBioSS_000580

MLS006011222

GTPL9130

SCHEMBL1424183

CHEBI:95033

KBio2_000580

KBio2_003148

KBio2_005716

KBio3_001039

KBio3_001040

DTXSID70274478

PYEFPDQFAZNXLI-UHFFFAOYSA-N

Bio1_000368

Bio1_000857

Bio2_000460

Bio2_000940

HMS1362N21

HMS1792N21

HMS1990N21

HMS3267N15

HMS3403N21

HMS3412G10

HMS3656J17

HMS3676G10

HMS3750E15

BCP02628

EX-A4551

BDBM50153835

NSC756654

3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methyl-phenyl]benzamide

3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]-benzamide

AKOS005266695

BCP9000021

CCG-100657

CS-0693

NSC-756654

SB19423

SDCCGSBI-0634838.P003

IDI1_002215

NCGC00025109-01

NCGC00025109-02

NCGC00025109-03

NCGC00025109-04

NCGC00025109-06

AS-73349

HY-13343

SMR004702983

ZM336372?

SW218185-2

ZM 336372, >=98% (HPLC)

SR-01000597402

SR-01000597402-1

BRD-K73789395-001-04-0

BRD-K73789395-001-05-7

BRD-K73789395-001-09-9

BRD-K73789395-001-10-7

BRD-K73789395-001-13-1

BRD-K73789395-001-14-9

Q27089299

ZM 336372 - CAS 208260-29-1

N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]4-hydroxybenzamide

3-dimethylamino-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide

1-(3-dimethylaminophenylcarboxamido)-3-(4-hydroxyphenylcarboxamido)-4-methylbenzene

106-467-8