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Mitragynine

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Identification
Molecular formula
C23H30N2O4
CAS number
4098-40-2
IUPAC name
3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol
State
State

At room temperature, Mitragynine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
190.00
Boiling point (Kelvin)
463.15
General information
Molecular weight
398.50g/mol
Molar mass
398.5040g/mol
Density
1.2004g/cm3
Appearence

Mitragynine typically appears as a white or slightly beige powder. It can also be found in leaf form as it is derived from the Kratom plant, native to Southeast Asia. The leaves are usually dark green.

Comment on solubility

Solubility of 3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol

The solubility of this complex organic compound, C23H30N2O4, presents some intriguing considerations. Solubility can be influenced by several factors, including:

  • Polarity: The presence of multiple hydroxyl groups (–OH) in the structure generally enhances solubility in polar solvents, such as water.
  • Hydrophobic Regions: The cyclobutylmethyl group adds a hydrophobic character, which can decrease solubility in polar solvents while potentially increasing solubility in nonpolar solvents.
  • Temperature: Increasing temperature may lead to enhanced solubility for many organic compounds, depending on their specific interaction with the solvent.

In general, it can be anticipated that while this compound may be soluble in polar protic solvents like alcohol, its solubility could be quite limited in pure water due to the bulky hydrophobic components. The interplay between hydrophilic and hydrophobic characteristics means that understanding the solubility profile requires *thorough investigation*, particularly in varying solvent systems.

To summarize, the solubility of this compound is likely to be:

  1. Moderate in polar solvents due to hydroxyl groups.
  2. Lower in water due to the hydrophobic cyclobutylmethyl group.
  3. Variable with temperature and solvent choice.

Ultimately, detailed experimental analysis is essential to determine the exact solubility characteristics in different conditions for optimal application or formulation.

Interesting facts

Interesting Facts about 3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol

This compound is a striking example of the complex structures that can arise in organic chemistry. Here are some notable points about it:

  • Structural Complexity: The intricate molecular structure of this compound is a testament to the vast array of possibilities in organic synthesis. Its fused ring system and multiple functional groups contribute to its unique chemical behavior.
  • Potential Applications: Compounds of this type often demonstrate interesting biological activities. Research into similar structures suggests they may have properties beneficial in medicinal chemistry, potentially serving as lead compounds in drug development.
  • Natural Analogues: Many naturally occurring alkaloids and phytochemicals share structural similarities with this compound, providing insight into its potential therapeutic effects. These relationships can lead to discoveries in pharmacology and biochemistry.
  • Challenges in Synthesis: The complexity of synthesizing such a molecule requires advanced techniques in organic synthesis, including strategies like multi-step synthesis, asymmetric synthesis, and the use of protecting groups.

As we further explore this fascinating compound, it's essential to consider its synthesis and application in scientific research. The journey of uncovering its properties could pave the way for new breakthroughs in various fields:

  1. Pharmaceutical research
  2. Material science
  3. Catalysis

In summary, 3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol is more than just a chemical name—it represents a gateway to understanding complex organic interactions and the potential for innovative applications in science.

Synonyms
N-Cyclobutylmethyl-14-hydroxydihydronormorphine
SCHEMBL6123677
CHEMBL5308404
Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, (5.alpha.,6.alpha.)-
NETZHAKZCGBWSS-UHFFFAOYSA-N
STL483711
L000735
17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol
(5.alpha.,6.alpha.)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol