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3-bromo-7-nitro-2H-indazole

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Identification
Molecular formula
C7H4BrN3O2
CAS number
860781-06-6
IUPAC name
3-bromo-7-nitro-2H-indazole
State
State

At room temperature, 3-bromo-7-nitro-2H-indazole is a solid.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
451.00
Boiling point (Kelvin)
724.15
General information
Molecular weight
255.03g/mol
Molar mass
255.0410g/mol
Density
1.8120g/cm3
Appearence

3-bromo-7-nitro-2H-indazole typically appears as a solid under standard conditions. Compounds similar in structure are often crystalline.

Comment on solubility

Solubility of 3-Bromo-7-nitro-2H-indazole (C7H4BrN3O2)

3-Bromo-7-nitro-2H-indazole is a compound with intriguing solubility characteristics, which are primarily influenced by its molecular structure. Understanding its solubility can reveal much about its potential applications and behavior in different environments. Here are some key points regarding the solubility of this compound:

  • Polar and Nonpolar Interactions: The presence of bromine (Br) and nitro (NO2) groups suggests that the molecule may have some degree of polarity, which partially affects its interaction with solvents.
  • Solvent Compatibility: It is likely to have moderate solubility in polar solvents such as dimethyl sulfoxide (DMSO) or ethanol due to the polar functional groups, while showing limited solubility in nonpolar solvents like hexane.
  • Temperature Influence: Like many organic compounds, the solubility of 3-bromo-7-nitro-2H-indazole may increase with temperature, allowing for higher concentrations in solution at elevated temperatures.
  • Application Insight: The solubility properties are crucial for its potential use in pharmaceuticals, where solubility can significantly affect bioavailability.

In summary, the solubility of 3-bromo-7-nitro-2H-indazole illustrates a balance between polar and nonpolar interactions, making it suitable for a variety of chemical environments. It can be effectively utilized in research and industry, particularly where soluble forms of the compound are desired.

Interesting facts

Interesting Facts about 3-bromo-7-nitro-2H-indazole

3-bromo-7-nitro-2H-indazole is a fascinating chemical compound that belongs to the indazole family. This unique compound has garnered attention for its potential applications in various fields, particularly in medicinal chemistry and material science. Here are some intriguing points to consider:

  • Pharmaceutical Potential: Compounds like 3-bromo-7-nitro-2H-indazole have been investigated for their biological activities, including anti-inflammatory and anticancer properties. Researchers aim to uncover its efficacy in drug development.
  • Structural Diversity: The presence of the bromine and nitro groups on the indazole core adds to its structural diversity, making it a valuable scaffold for synthesizing derivative compounds with tailored properties.
  • Interaction with Biological Targets: The nitro group may participate in various chemical reactions, potentially modulating the interactions with biological macromolecules, while the bromine atom can influence the lipophilicity and biomolecular recognition.
  • Synthetic Approaches: The synthesis of 3-bromo-7-nitro-2H-indazole involves interesting reaction pathways, including halogenation and nitration of the indazole framework, showcasing the intricacies of organic synthesis.

"Exploring the complexities of compounds like 3-bromo-7-nitro-2H-indazole not only advances our understanding of chemical properties but also paves the way for innovations in drug discovery."

This compound is also a prime example of how small changes in molecular structure can lead to significantly different biological activities, making it an exciting topic of study for chemists and biologists alike.

Synonyms
3-bromo-7-nitroindazole
3-Bromo-7-nitro-1H-indazole
74209-34-0
3-bromo-7-nitro-2H-indazole
MFCD00159910
3-bromo-7NI
CHEMBL479014
1H-Indazole,3-bromo-7-nitro-
SR-01000075708
3-Br-7-NI
Bromo-7-nitroindazole
Tocris-0735
Lopac-B-2050
3-Br-7NI
Lopac0_000161
BSPBio_001502
BSPBio_002434
KBioGR_000222
KBioSS_000222
SCHEMBL499421
SCHEMBL499422
SPECTRUM1505105
GTPL5113
BCBcMAP01_000129
KBio2_000222
KBio2_002790
KBio2_005358
KBio3_000443
KBio3_000444
DTXSID90274319
3-Bromo-7-nitro-1H-indazole #
Bio1_000424
Bio1_000913
Bio1_001402
Bio2_000222
Bio2_000702
HMS1361L04
HMS1791L04
HMS1989L04
HMS3260B03
HMS3266N19
HMS3402L04
HMS3411F05
HMS3649K16
HMS3675F05
Tox21_500161
BDBM50270528
HSCI1_000239
AKOS005070136
AKOS040732289
CCG-204256
CS-W020666
DB01997
LP00161
PB13032
SB19947
SDCCGSBI-0050149.P002
IDI1_033972
NCGC00015143-01
NCGC00015143-02
NCGC00015143-03
NCGC00015143-04
NCGC00015143-05
NCGC00015143-06
NCGC00015143-07
NCGC00015143-08
NCGC00015143-09
NCGC00015143-10
NCGC00024756-01
NCGC00024756-02
NCGC00024756-03
NCGC00024756-04
NCGC00024756-05
NCGC00024756-06
NCGC00024756-07
NCGC00024756-08
NCGC00260846-01
DA-49570
PD015402
SY097431
HY-101175
EU-0100161
NS00069465
A15928
B 2050
EN300-316473
M01376
Bromo-7-nitroindazole [3-Bromo-7-nitroindazole]
1W-0945
3-Bromo-7-nitroindazole, >=98% (TLC), powder
SR-01000075708-1
SR-01000075708-3
SR-01000075708-6
BRD-K24689407-001-03-0
BRD-K24689407-001-04-8
BRD-K24689407-001-05-5
BRD-K24689407-001-06-3
Q27073725
Z1269214315
636-128-4