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Quinuclidine

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Identification
Molecular formula
C7H13N
CAS number
100-76-5
IUPAC name
3-azabicyclo[3.2.2]nonane
State
State

At room temperature, quinuclidine is a solid. It is often encountered as stable, crystalline structures that are colorless to white.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
149.00
Boiling point (Kelvin)
422.20
General information
Molecular weight
137.23g/mol
Molar mass
137.2320g/mol
Density
1.0814g/cm3
Appearence

Quinuclidine is a white crystalline solid. It has a characteristic, amine-like odor.

Comment on solubility

Solubility of 3-azabicyclo[3.2.2]nonane

The solubility of 3-azabicyclo[3.2.2]nonane can be an intriguing topic as it showcases the interplay of molecular structure with solvent interactions. Its unique bicyclic structure impacts how it interacts with various solvents, and understanding this solubility is vital for its applications in different chemical environments.

General Solubility Characteristics

3-azabicyclo[3.2.2]nonane is largely soluble in:

  • Polar solvents - due to the presence of the amine functional group, which can engage in hydrogen bonding.
  • Aromatic hydrocarbons - offering compatibility through dispersion forces and π–π interactions.
  • Some alcohols - as they can disrupt intermolecular forces and solvate the bicyclic structure.

Solubility Challenges

Despite its solubility in certain solvents, 3-azabicyclo[3.2.2]nonane may face challenges with:

  • Low polarity solvents - such as alkanes, where solubility tends to be quite limited.
  • Highly nonpolar environments - which do not favorably interact with polar functional groups.

In summary, the solubility of 3-azabicyclo[3.2.2]nonane is influenced significantly by its chemical structure, predominantly displaying solubility in polar and aromatic solvents while exhibiting limited solubility in nonpolar solvents. This characteristic underscores the importance of selecting the right solvent in practical applications.

Interesting facts

Interesting Facts about 3-azabicyclo[3.2.2]nonane

3-azabicyclo[3.2.2]nonane, a fascinating bicyclic compound, showcases the brilliant complexities found within organic chemistry. This unique structure comprises a nitrogen atom incorporated into a bicyclic framework, resulting in a compound that has garnered significant interest for several reasons:

  • Structural Intricacy: The bicyclic nature of 3-azabicyclo[3.2.2]nonane contributes to its unique three-dimensional shape, which plays a crucial role in its chemical behavior and interactions.
  • Psychoactive Properties: This compound belongs to a class often explored for potential psychoactive properties, making it a subject of interest in medicinal chemistry and pharmaceutical research.
  • Synthetic Route: The synthesis of 3-azabicyclo[3.2.2]nonane often requires sophisticated techniques, including multi-step reactions, showcasing the creativity and technical skills required in the field of synthetic organic chemistry.

Interestingly, researchers have studied 3-azabicyclo[3.2.2]nonane as a potential scaffold for developing novel pharmacological agents. The ability to modify its structure can lead to a variety of derivatives, which may exhibit enhanced efficacy or selectivity for biological targets.

As noted by chemists, this compound serves as *both a challenge and an opportunity* in the development of new materials and therapies. Its intriguing properties symbolize the broader quest in chemistry to unlock the potential of complex organic molecules for practical applications.

In summary, 3-azabicyclo[3.2.2]nonane is more than just a chemical compound; it represents the intersection of structural innovation and potential applications in science, making it a key player in ongoing chemical research.

Synonyms
3-Azabicyclo[3.2.2]nonane
283-24-9
3-AZABICYCLO(3.2.2)NONANE
NSC 78443
BRN 0878218
AI3-26871
DTXSID7059771
5-20-04-00370 (Beilstein Handbook Reference)
NSC78443
MFCD00167979
SCHEMBL212630
3-aza-bicyclo[3.2.2]nonane
SCHEMBL2388239
CHEMBL2079064
DTXCID9037795
3-aza-bicyclo[3.2.2] nonane
3-Aza-bicyclo-[3.2.2]nonane
NSC-78443
STK689059
AKOS005601271
AKOS006337412
NCGC00340911-01
SY278854
DB-067919
CS-0054142
AB01332690-02
EN300-4324319
3-Azabicyclo[3.2.2]nonane, hydrochloride (1:1)