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3-Aminopropyl(methyl)phosphinic acid

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Identification
Molecular formula
C4H12NO2P
CAS number
26096-86-6
IUPAC name
3-aminopropyl(methyl)phosphinic acid
State
State

At room temperature, 3-Aminopropyl(methyl)phosphinic acid is a solid. It is a stable crystalline compound, making it easy to handle under standard laboratory conditions. This state facilitates its use in various chemical syntheses and research applications.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
495.15
Boiling point (Kelvin)
768.30
General information
Molecular weight
139.12g/mol
Molar mass
139.1170g/mol
Density
1.1500g/cm3
Appearence

3-Aminopropyl(methyl)phosphinic acid appears as a white crystalline solid. It is typically available in purified form for laboratory use and can be characterized by its high solubility in water, contributing to its clear and uniform crystalline appearance.

Comment on solubility

Solubility of 3-aminopropyl(methyl)phosphinic acid

3-aminopropyl(methyl)phosphinic acid, with the chemical formula C4H12NO2P, exhibits notable solubility characteristics that are essential for its applications in various fields. The presence of both an amino group and a phosphinic acid moiety contributes to its solubility profile.

Key Factors Influencing Solubility:

  • Polarity: The compound's functional groups enhance its polarity, making it more soluble in polar solvents, such as water.
  • pH Dependence: The solubility can vary with pH, as the ionization of the phosphinic acid group can affect the overall solubility in aqueous solutions.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amino and carboxylic acid functionalities can further increase solubility in certain solvents.

It is often reported that, *"solubility in water aids the bioavailability of phosphinic compounds,"* and 3-aminopropyl(methyl)phosphinic acid is no exception. This characteristic allows it to be effectively utilized in biochemical applications where aqueous solubility is critical.

In summary, the solubility of 3-aminopropyl(methyl)phosphinic acid can be described as:

  • Good solubility in polar solvents
  • Variable solubility influenced by pH levels
  • Enhanced solubility due to the ability to form hydrogen bonds

Understanding these solubility properties is essential for researchers and practitioners working with this compound.

Interesting facts

Interesting Facts About 3-Aminopropyl(methyl)phosphinic Acid

3-Aminopropyl(methyl)phosphinic acid is a fascinating compound in the realm of organic phosphorus chemistry. Here are some key insights:

  • Biological Significance: This compound plays a vital role in biochemical research. Its structural features make it an interesting candidate for studying enzyme activities and interactions at the molecular level.
  • Applications: 3-Aminopropyl(methyl)phosphinic acid is often utilized in the formulation of pharmaceuticals and agrochemicals. Its unique properties may aid in the development of novel drugs with specific therapeutic targets.
  • Synthesis: A variety of synthetic routes have been developed to obtain this phosphinic acid. These include methods employing classical organic synthesis techniques as well as more innovative approaches involving transition metal catalysis.
  • Amine Functionality: The presence of both amino and phosphinic acid functional groups allows this compound to participate in various chemical reactions, enhancing its utility in organic synthesis.
  • Research Potential: The compound is increasingly coming under investigation for its potential roles in treating neurological disorders, owing to its phosphonic acid moiety, which can mimic the action of neurotransmitters.

In summary, 3-aminopropyl(methyl)phosphinic acid is not only a significant research compound due to its diverse applications but also a synthetic challenge that excites chemists who are interested in the intersections of organic and medicinal chemistry.

Synonyms
127729-35-5
3-aminopropyl(methyl)phosphinic Acid
3-Apmpa
SKF 97541
skf-97541
SK&F 97541
CGP 35024
CGP35024
(3-aminopropyl)methylphosphinic acid
(3-aminopropyl)(methyl)phosphinic acid
(3-(Aminopropyl)methyl)phosphinic acid
Phosphinic acid, (3-aminopropyl)methyl-
SKF97541
Phosphinic acid, P-(3-aminopropyl)-P-methyl-
Phosphinic acid, (3-(aminopropyl)methyl)-
CHEMBL112710
DTXSID80925969
SKF 97541 hydrochloride
3-aminopropyl-methylphosphinic acid
(R)-(3-aminopropyl)methylphosphinic acid
SKF-97541;SKF97541;CGP 35024;CGP-35024;CGP35024
C4H12NO2P
SR-01000076225
QD7
CGP-35024
SKF-97,541
Tocris-0379
Lopac-A-196
Biomol-NT_000257
Lopac0_000098
SCHEMBL341867
BPBio1_001014
GTPL1080
BDBM24185
3-aminopropylmethylphosphinic acid
CHEBI:232376
DTXCID401354789
HB0954
PDSP1_001483
PDSP2_001467
STK538161
3-aminopropylphosphinic derivative, 2
AKOS005468710
AT41793
CCG-204193
SK F 97541
NCGC00015015-01
NCGC00015015-02
NCGC00015015-03
NCGC00015015-04
NCGC00015015-05
NCGC00024562-01
NCGC00024562-02
NCGC00024562-03
HY-100915
CS-0020585
L000069
Q7390605
SR-01000076225-3
802-793-6