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4, Aminophenol

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Identification
Molecular formula
C10H16N2O4S
CAS number
2801-59-8
IUPAC name
3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide
State
State

At room temperature, 3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide is a solid. It is typically stable under recommended storage conditions. Store in a cool, dry, well-ventilated area away from incompatible substances.

Melting point (Celsius)
138.50
Melting point (Kelvin)
411.65
Boiling point (Celsius)
301.50
Boiling point (Kelvin)
574.65
General information
Molecular weight
232.26g/mol
Molar mass
232.2550g/mol
Density
1.2600g/cm3
Appearence

3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide is typically a white to off-white crystalline solid. It is often found in powdered form, and can be hygroscopic, absorbing moisture from the air.

Comment on solubility

Solubility of 3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide (C10H16N2O4S)

The solubility of 3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide is a subject of interest, especially in the context of its applications in pharmaceuticals and biochemistry. This compound is expected to display a notable water solubility due to its structural characteristics.

Factors Influencing Solubility

The solubility of this compound can be attributed to several key factors:

  • Interaction with Water: The presence of the amino group (–NH2) and hydroxyl groups (–OH) enhances its ability to form hydrogen bonds with water molecules, increasing solubility.
  • Sulfonamide Group: The sulfonamide moiety (–SO2NH2) contributes to its polar nature, facilitating its presence in aqueous solutions.
  • Solvent Characteristics: Polar solvents like ethanol or methanol may also dissolve the compound effectively, although water remains the primary solvent of concern.

Practical Implications

In practical applications, solubility impacts the bioavailability and pharmacodynamics of the compound. Greater solubility typically translates to:

  • Improved absorption in biological systems.
  • Enhanced efficacy in various applications.
  • Facilitation of formulation processes in drug development.

In conclusion, the solubility of 3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide not only defines its chemical behavior but also plays a crucial role in its practical utility, making it a compound of significant interest in chemical sciences.

Interesting facts

Interesting Facts About 3-Amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide

3-Amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide, often referred to as a sulfamide compound, is notable in both medicinal and synthetic chemistry realms. Here are some compelling aspects of this compound:

  • Medical Applications: This compound belongs to a class of sulfonamides, which are known for their antibacterial properties. Sulfonamides were some of the first antibiotics discovered and have paved the way in bacterial infection treatment.
  • Structure and Functionality: The presence of both amino and hydroxyethyl groups significantly enhances its solubility and reactivity. These functional groups can play crucial roles in biological systems, impacting interaction with enzymes and receptors.
  • Dual Hydroxyethyl Groups: The bis(2-hydroxyethyl) moiety may not only enhance solubility but also provide sites for further chemical modifications, making it a versatile building block in drug design.
  • Research Potential: Ongoing studies involve exploring the compound's applications in targeted drug delivery systems and its potential as a therapeutic agent for various conditions, including cancers and metabolic disorders.
  • Environmental Impact: Given its chemical nature, understanding the degradation patterns and environmental impact of such compounds is crucial as they can enter aquatic systems through pharmaceutical runoff.

As we delve deeper into the world of chemical compounds, 3-amino-N,N-bis(2-hydroxyethyl)benzenesulfonamide represents the intersection of medicinal chemistry and environmental science, reminding us of the delicate balance in synthetic chemistry.

Engaging with compounds like these not only enriches our understanding but also highlights the complex relationships between structure, function, and application in real-world scenarios. As one scientist aptly put it, "The lines between chemistry and life are often blurred, and therein lies the beauty of our scientific journey."

Synonyms
6374-97-6
N1,N1-BIS(2-HYDROXYETHYL)METANILAMIDE
3-amino-n,n-bis(2-hydroxyethyl)benzenesulfonamide
NSC151166
SCHEMBL5035257
DTXSID80980255
ZINC03873795
AKOS010375206
Metanilamide,N1-bis(2-hydroxyethyl)-
NSC-151166
Benzenesulfonamide,N-bis(2-hydroxyethyl)-
3-Amino-N,N-bis(2-hydroxyethyl)benzene-1-sulfonamide
622-701-6