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Histidine amide

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Identification
Molecular formula
C9H15N3O
CAS number
693-56-3
IUPAC name
3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide
State
State

At room temperature, histidine amide exists as a solid. It is stable under standard temperature and pressure conditions.

Melting point (Celsius)
246.00
Melting point (Kelvin)
519.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
183.22g/mol
Molar mass
183.2210g/mol
Density
1.2145g/cm3
Appearence

Histidine amide generally appears as a white to off-white crystalline powder. It is often used in scientific research and is a derivative of the amino acid histidine.

Comment on solubility

Solubility of 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide

The compound 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide, with the chemical formula C9H15N3O, exhibits notable solubility characteristics that are influenced by its molecular structure. Generally, the solubility of this compound can be understood through several key points:

  • Hydrophilic Groups: The presence of amino and carbonyl groups in its structure contributes to enhanced solubility in polar solvents, particularly in water.
  • Imidazole Ring: The imidazole moiety can engage in hydrogen bonding with water, further facilitating solubility.
  • Solvent Compatibility: This compound is likely to dissolve well in organic solvents as well, especially those with polar character.
  • Temperature Dependency: As with many compounds, solubility may increase with temperature, allowing for higher concentrations in solution.

In summary, the solubility of 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide can be described as favorable in polar environments due to its functional groups, enabling various applications in biological and chemical contexts. Thus, it’s essential to consider solubility profiles when preparing solutions for experimental use.

Interesting facts

Exploring 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide

3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide is a fascinating compound that brings together several key elements of biological chemistry. Primarily known for its role in various biological systems, this compound showcases the intricate relationship between structure and function in chemical compounds.

Key Features

  • Functional Groups: The compound contains an amino group and a propanamide moiety, which contribute to its basicity and ability to form hydrogen bonds. These properties can significantly influence its reactivity and interactions with biological molecules.
  • Imidazole Presence: The 1H-imidazole ring is a feature commonly found in many biologically active molecules, including histidine, an essential amino acid. This ring imparts unique biochemical properties, facilitating various actions, such as enzyme catalysis and metal ion coordination.
  • Pharmaceutical Relevance: Compounds with similar structures are often investigated for their potential medicinal properties. Research has indicated that they might be involved in processes such as anti-inflammatory responses and neurotransmitter activity, making them valuable in drug design.
  • Synthesis and Derivation: The synthesis of this compound can involve multiple steps, often utilizing various reagents and conditions to ensure the correct functional groups are introduced without compromising the integrity of the imidazole ring.

"The beauty of organic chemistry lies in understanding how the smallest changes in molecular structure can lead to the most significant transformations in biological activity."

Research Implications

Studies involving 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide highlight its potential impact in drug development, especially in targeting specific biological pathways. As scientists continue to explore its properties and interactions, the compound remains a subject of keen interest in the fields of medicinal chemistry and pharmacology.

In conclusion, the distinct combination of functional groups, along with the imidazole ring, positions 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide as a noteworthy compound in chemical and biochemical research, making it an exciting topic for enthusiasts and professionals alike.

Synonyms
Carcinine
56897-53-1
N-(2-(1H-Imidazol-5-yl)ethyl)-3-aminopropanamide
Carcinine ditrifluoroacetate
beta-Alanylhistamine
3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide
UNII-WIV0W167TC
WIV0W167TC
Alistin
beta-alaninylhistamine
DECARBOXY CARNOSINE
.BETA.-ALANYLHISTAMINE
CHEBI:131429
DTXSID90205421
Propanamide, 3-amino-N-(2-(1H-imidazol-4-yl)ethyl)-
N-[2-(1H-imidazol-4-yl)ethyl]-beta-alaninamide
N-[2-(1H-imidazol-5-yl)ethyl]-beta-alaninamide
PROPANAMIDE, 3-AMINO-N-(2-(1H-IMIDAZOL-5-YL)ETHYL)-
N-(2-(1H-imidazol-4-yl)ethyl)-beta-alaninamide
3-amino-N-(2-(1H-imidazol-5-yl)ethyl)propanamide
SPBio_002343
beta-alanyl-histamine
N-beta-alanylhistamine
Carcinine [WHO-DD]
Prestwick0_000422
Prestwick1_000422
Prestwick2_000422
Prestwick3_000422
Lopac-C-2321
Lopac0_000210
BSPBio_000404
MLS002153803
BPBio1_000446
CHEMBL461024
SCHEMBL2819350
SCHEMBL19051459
CHEBI:95262
DTXCID90127912
HMS1569E06
HMS2096E06
HMS2235I06
HMS3371N06
AKOS006271690
AKOS013465881
CCG-204305
SMP2_000161
NCGC00015221-01
NCGC00015221-02
NCGC00015221-03
SMR001233178
CAS-56897-53-1
DB-343483
HY-107567
CS-0028884
C16003
EN300-8092791
3-amino-N-[2-(1H-imidazol-4-yl)ethyl]propanamide
Q27892933
Z1198154574
HJD