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Pyridoxal isonicotinoyl hydrazone

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Identification
Molecular formula
C10H9N3O
CAS number
65666-07-1
IUPAC name
3-amino-5-(4-pyridyl)-1H-pyridin-2-one
State
State

At room temperature, this compound is typically found in a solid state. It is often supplied as a stable crystalline powder, making it convenient for handling and storage in laboratory conditions.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
321.00
Boiling point (Kelvin)
594.00
General information
Molecular weight
186.20g/mol
Molar mass
186.1880g/mol
Density
1.2970g/cm3
Appearence

The compound typically appears as a solid in its pure form. It is often encountered as a crystalline powder, which can vary in color from white to off-white. The actual color can depend on the specific purity and form of the sample.

Comment on solubility

Solubility of 3-amino-5-(4-pyridyl)-1H-pyridin-2-one

The solubility of 3-amino-5-(4-pyridyl)-1H-pyridin-2-one (C10H9N3O) can be described through various important factors:

  • Polarity: This compound contains polar functional groups, which typically enhances solubility in polar solvents.
  • Hydrogen Bonding: The presence of amino groups can facilitate hydrogen bonding, further increasing solubility in water.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents such as water and alcohols compared to non-polar solvents.
  • Temperature Dependence: Solubility may increase with temperature, a common trend observed with many organic compounds.
  • Structural Considerations: The aromatic pyridine rings may also influence solubility by impacting the compound's overall shape and steric hindrance.

In conclusion, while specific solubility data may vary, one can infer that 3-amino-5-(4-pyridyl)-1H-pyridin-2-one is expected to display moderate to good solubility in polar solvents due to its structural attributes and functional groups. As with any compound, laboratory experimentation is essential to determine precise solubility characteristics.

Interesting facts

Interesting Facts about 3-amino-5-(4-pyridyl)-1H-pyridin-2-one

3-amino-5-(4-pyridyl)-1H-pyridin-2-one is a fascinating and versatile heterocyclic compound that has garnered attention in various fields of research. Here are some intriguing aspects of this compound:

  • Pharmaceutical Applications: This compound exhibits potential as a leading structure in drug discovery, particularly in the development of antitumor and antimicrobial agents. Its structural similarities to known bioactive molecules make it a suitable candidate for further exploration.

  • Novel Ligand: 3-amino-5-(4-pyridyl)-1H-pyridin-2-one can function as a chelator for metal ions, forming complexes that hold potential in catalysis and materials science.

  • Biological Importance: Research has indicated that this compound may play a role in targeting specific biological pathways, making it a topic of interest in understanding disease mechanisms and developing therapeutics.

  • Structure-Activity Relationship (SAR): The molecular structure of 3-amino-5-(4-pyridyl)-1H-pyridin-2-one allows for modifications that can enhance its activity. This makes it an excellent candidate for SAR studies aimed at optimizing drug efficacy.

  • Research Opportunities: Ongoing research continues to unveil its interactions with biological targets. Advancements in techniques such as molecular docking and structural biology have paved the way for a deeper understanding of this molecule.

As a compound that bridges various fields, 3-amino-5-(4-pyridyl)-1H-pyridin-2-one embodies the intricacies of chemical research while offering promising avenues for innovation in drug design and beyond.

Synonyms
Amrinone
60719-84-8
inamrinone
Inocor
Wincoram
Cordemcura
Cartonic
Amcoral
Vesistol
Amrinonum [INN-Latin]
Amrinona [INN-Spanish]
5-Amino-[3,4'-bipyridin]-6(1H)-one
Win-40680
Amrinona
3-Amino-5-(4-pyridinyl)-2(1H)-pyridinone
5-Amino-(3,4'-bipyridin)-6(1H)-one
3-amino-5-pyridin-4-yl-1H-pyridin-2-one
WIN 40680
[3,4'-Bipyridin]-6(1H)-one, 5-amino-
Amrinone [INN]
Amcoral (TN)
CCRIS 3794
AWD 08-250
Inamrinone [USAN:USP]
EINECS 262-390-0
NSC-759805
BRN 0744819
Amrinone lactate
MLS000069829
5-Amino(3,4'-bipyridin)-6(1H)-one
DTXSID9022603
AMRINONE [JAN]
AMRINONE [MI]
AMRINONE [VANDF]
INAMRINONE [USAN]
MFCD00083228
AMRINONE [MART.]
INAMRINONE [VANDF]
Inocor (TN)
AMRINONE [USP-RS]
AMRINONE [WHO-DD]
5-amino-3,4'-bipyridin-6(1H)-one
(3,4'-BIPYRIDIN)-6(1H)-ONE, 5-AMINO-
3-amino-5-(pyridin-4-yl)pyridin-2-ol
SMR000058850
CHEMBL12856
CHEBI:2686
DTXCID602603
JUT23379TN
Amrinon
INAMRINONE [USP IMPURITY]
C01CE01
INAMRINONE [USP MONOGRAPH]
5-25-15-00181 (Beilstein Handbook Reference)
3-amino-5-pyridin-4-ylpyridin-2-ol
3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one
NSC 759805
5-Amino[3,4'-bipyridin]-6(1H)-one
NCGC00164379-01
Amrinonum
Amrinonum (INN-Latin)
5-Amino(3,4'-bipyridine)-6-(1H)-one
Amrinona (INN-Spanish)
CAS-60719-84-8
Inamrinone (USAN:USP)
AMRINONE (MART.)
5-AMINO-3,4'-BIPYRIDYL-6(1H)-ONE
AMRINONE (USP-RS)
3-Amino-5-(4-pyridinyl)-1,2-dihydro-2-pyridone
INAMRINONE (USP IMPURITY)
INAMRINONE (USP MONOGRAPH)
Inamrinone (USP)
3-amino-5-(pyridin-4-yl)pyridin-2(1H)-one
5-Amino-(3,4'-bipyridine)-6(1H)-one
Amrinone (JAN/INN)
UNII-JUT23379TN
Prestwick_44
Amrinone,(S)
Amrinone (Standard)
Spectrum_001350
Opera_ID_1054
Prestwick0_000800
Prestwick1_000800
Prestwick2_000800
Prestwick3_000800
Spectrum2_001980
Spectrum3_000956
Spectrum4_001069
Spectrum5_000999
cid_3698
SCHEMBL44012
BSPBio_000940
KBioGR_001398
KBioSS_001830
MLS001074083
DivK1c_000136
SPECTRUM1503084
SPBio_002139
SPBio_002879
BPBio1_001034
GTPL7202
SCHEMBL13457017
BDBM34651
HMS500G18
HY-B1294R
KBio1_000136
KBio2_001830
KBio2_004398
KBio2_006966
KBio3_002052
NINDS_000136
HMS1570O22
HMS2097O22
HMS2234F12
HMS3264E16
HMS3369J10
HMS3714O22
Pharmakon1600-01503084
BCP12764
HY-B1294
Tox21_112110
Tox21_301847
CCG-39487
NSC759805
STK590307
AKOS005512516
Tox21_112110_1
DB01427
FA17893
KS-5178
CID 5281003
IDI1_000136
NCGC00016896-01
NCGC00016896-02
NCGC00016896-03
NCGC00016896-04
NCGC00016896-06
NCGC00095984-01
NCGC00255137-01
AC-12186
AC-33137
SY112917
3-Amino-5-(4-pyridinyl)-2(1H)pyridinone
3-azanyl-5-pyridin-4-yl-1H-pyridin-2-one
CS-0013064
NS00001039
C75837
D00231
AB00052312-04
AB00052312_05
EN300-6477374
A832852
Q422724
SR-00000002445
SR-00000002445-2
BRD-K45924332-001-04-4
BRD-K45924332-001-07-7
BRD-K45924332-001-16-8
Z1198150288
5-Amino-[3,4 inverted exclamation mark -bipyridin]-6(1H)-one
Amrinone, United States Pharmacopeia (USP) Reference Standard
Amrinone;3-Amino-5-(4-pyridinyl)-1,2-dihydro-2-pyridone;5-Amino-1,6-dihydro-6-oxo-[3,4'-bipyridine]