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S-adenosylmethionine

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Identification
Molecular formula
C15H22N6O5S
CAS number
29908-03-0
IUPAC name
(3-amino-3-carboxy-propyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl]-methyl-sulfonium
State
State

At room temperature, S-adenosylmethionine is in a solid state, usually found as a powder due to its hygroscopic nature, which means it can absorb moisture from the air. Storage conditions are critical to maintain its stability and to prevent decomposition or loss of potency.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
398.44g/mol
Molar mass
398.4370g/mol
Density
1.2800g/cm3
Appearence

S-adenosylmethionine is typically found as a white to off-white crystalline powder. It may also appear as an amorphous powder, depending on the formulation and specific conditions like pH and humidity.

Comment on solubility

Solubility of (3-amino-3-carboxy-propyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl]-methyl-sulfonium

The solubility of the compound (3-amino-3-carboxy-propyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl]-methyl-sulfonium, represented by the chemical formula C15H22N6O5S, can be quite complex due to its intricate structure and functional groups.

Several factors influence its solubility:

  • Polarity: The presence of multiple functional groups, such as amino and carboxylic acid groups, suggests that the compound may exhibit polar characteristics, which generally enhance solubility in polar solvents like water.
  • Hydrogen Bonding: Functional groups capable of forming hydrogen bonds contribute positively to solubility in aqueous solutions. The compound's structure likely enables significant hydrogen bonding opportunities with solvent molecules.
  • Sulfonium Ion: As a sulfonium compound, its ability to interact with various solvents, including polar and non-polar solvents, may enhance solubility under certain conditions.

Conversely, due to its relatively large and complex structure, its solubility might be limited in non-polar solvents, highlighting the importance of solvent choice in practical applications.

For experimental considerations, it is advisable to test solubility in a range of solvents to fully understand its behavior, as specific interactions can significantly alter solubility profiles.

In conclusion, the solubility of this compound is expected to be influenced primarily by its polarity and functional group interactions, making a direct assessment essential for any practical applications.

Interesting facts

Interesting Facts about (3-amino-3-carboxy-propyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl]-methyl-sulfonium

This fascinating compound is a complex organic molecule that incorporates multiple functional groups, making it of great interest in the fields of biochemistry and medicinal chemistry. Here are some intriguing aspects of this compound:

  • Diverse Functional Groups: The structure features amino, carboxyl, and sulfonium groups, which contribute to its reactivity and interactions with biological systems.
  • Connection to Nucleic Acids: The presence of the 6-aminopurine moiety suggests it may be involved in processes related to nucleic acids, like DNA and RNA, potentially influencing gene expression or cellular metabolism.
  • Biological Activity: Compounds of this nature are often explored for their potential as therapeutic agents, with the goal of targeting specific biological pathways or disorders.
  • Tetrahydrofuran Ring: The inclusion of a tetrahydrofuran ring indicates that the compound may exhibit unique stereochemical properties that can affect its pharmacological profile.
  • Sulfation: The methyl-sulfonium part of the molecule may play a role in cell signaling or modification of protein structures, highlighting the compound's potential functional versatility.

This compound embodies the intricate relationship between chemical structure and biological function, exemplifying how subtle changes in molecular composition can lead to significant variations in activity and application. As research in this area advances, such compounds may lead to groundbreaking discoveries in health and disease management.

Synonyms
(+)-[6]-Gingerol; (S)-(+)-[6]Gingerol; (S)-[6]Gingerol
SCHEMBL7810282
CHEMBL3560400
DTXSID50860318
CHEBI:194378
S-(5'-Adenosyl)-L-methionine (SAM)
NS00014313
(3-amino-3-carboxypropyl)({[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium
(3-amino-3-carboxypropyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulanium
(3-Amino-3-carboxypropyl){[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}methylsulfanium