Streptomycin | Solubility of Things

Identification

Molecular formula

C₂₁H₃₉N₇O₁₂

CAS number

57-92-1

IUPAC name

[3-amino-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate

State

At room temperature, streptomycin is typically in a solid state as a powder. It is stable under normal environmental conditions but should be kept dry and stored appropriately to maintain its efficacy.

Melting point (Celsius)

169.00

Melting point (Kelvin)

442.15

Boiling point (Celsius)

296.00

Boiling point (Kelvin)

569.15

General information

Molecular weight

581.57g/mol

Molar mass

581.5690g/mol

Density

1.5700g/cm³

Appearence

Streptomycin appears as a white or slightly yellowish crystalline powder. It is often odorless or has a slight characteristic odor.

Comment on solubility

Solubility of 3-amino-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate

The solubility of 3-amino-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate (C₂₁H₃₉N₇O₁₂) can be characterized by several factors:

Polarity: Due to the presence of multiple hydroxyl groups and nitrogen atoms, this compound exhibits significant polarity, which may enhance its ability to dissolve in polar solvents.
Hydrophilicity: The numerous hydroxyl and amino groups suggest that the compound is likely to have good solubility in water.
Molecular Weight: With a molecular weight of 447.56 g/mol, it is crucial to consider that larger molecules tend to have intricate solubility properties.
Interactions: The potential for hydrogen bonding with water could also play a vital role in solvation dynamics.

In conclusion, while specific experimental data would provide the most accurate insight, 3-amino-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate is expected to be reasonably soluble in polar solvents, especially water, due to its hydrophilic nature. The balance of various functional groups highlights the intricate nature of its solubility behavior.

Interesting facts

Interesting Facts about 3-amino-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate

This fascinating compound is a complex molecule with significant implications in both pharmaceutical and biochemical research. Below are some noteworthy aspects:

Pharmacological Potential: The structural components of this compound suggest it could have applications in drug development, particularly in the field of enzyme inhibitors and antitumor agents.
Amino Acid Composition: The presence of the amino group in the molecule indicates its potential role in biological systems, acting as a precursor for protein synthesis or as a neurotransmitter modulator.
Multi-Functional Groups: The compound features multiple functional groups, including hydroxy and phosphate moieties, which can enhance its reactivity and potential interactions with biological targets.
Nucleobase Similarities: Given that part of its structure resembles nucleobases, it may also participate in nucleic acid interactions, warranting further investigation into its capacity to affect genetic material.
Importance of Tetrahydrofuran Backbone: The tetrahydrofuran component not only contributes to the compound's stability but also plays a critical role in the biological activity by potentially altering the lipophilicity of the molecule.

As a scientist delving into the study of such a compound, one could explore its potential in therapeutic applications, investigate its mechanisms of action, and evaluate how its intricate structure affects biological systems. The challenge lies in synthesizing this compound efficiently and determining its viability in practical scenarios.

With ongoing research in the fields of medicinal chemistry and molecular biology, compounds like this represent a frontier where knowledge about molecular interactions and therapeutic agents converges.