Interesting facts
Interesting Facts about 3-(allylsulfanylmethyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
This unique compound, known for its complex structure, belongs to a class of molecules known as benzothiadiazines, which are noteworthy for their diverse pharmacological applications. Here are some interesting facts:
- Medical Relevance: Compounds in this class often exhibit various biological activities, including antimicrobial, antihypertensive, and potential anticancer properties, making them a focus of research in medicinal chemistry.
- Structural Complexity: The intricate arrangement of the benzothiadiazine moiety coupled with the substituents provides a rich field for structure-activity relationship (SAR) studies. This allows scientists to tailor the compound's properties for specific therapeutic effects.
- Chlorine Influence: The presence of chlorine in its structure often enhances the compound’s lipophilicity and biological activity, which can facilitate cellular uptake and bioavailability.
- Sulfonamide Backbone: As a sulfonamide, this compound may exhibit similar characteristics to antibiotics in this class, potentially allowing for synergistic effects when combined with other compounds.
- Versatile Functional Group: The allylsulfanylmethyl group is a notable feature, which may contribute to the compound’s overall activity by acting as a reactive site for further chemical modifications.
In summary, the significance of 3-(allylsulfanylmethyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide lies in its potential for medicinal applications stemming from its fascinating structure and reactivity. As a compound that combines various functional groups, it could serve as a template for developing new therapeutics targeting various diseases.
Synonyms
althiazide
Altizide
5588-16-9
Altizida
(-)-Altizide
Altizide, (+)-
Althiazide [USAN]
Altizidum
6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
Altizide [INN]
Altizidum [INN-Latin]
Altizida [INN-Spanish]
GI8CB72B0D
Altizide (INN)
NSC-757786
Althiazide (USAN)
3-((Allylthio)methyl)-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
DTXSID3045857
EINECS 226-994-8
P-1779
ALTIZIDE [MART.]
ALTIZIDE [WHO-DD]
CB 8093
ALTIZIDE [EP IMPURITY]
ALTIZIDE [EP MONOGRAPH]
133562-97-7
133585-76-9
DTXCID1025857
3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide
NSC 757786
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (+)-
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (-)-
NCGC00094855-01
Altizidum (INN-Latin)
Altizida (INN-Spanish)
ALTIZIDE (MART.)
3-Allylthiomethyl-6-chlor-3,4-dihydro-2H-1,2,4-benzothiadiazin-7-sulfonamid 1,1-dioxid
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-, 1,1-dioxide
3-((Allylthio)methyl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
ALTIZIDE (EP IMPURITY)
ALTIZIDE (EP MONOGRAPH)
6-Chloro-3,4-dihydro-3-((2-propenylthio)methyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
(+)-Altizide
D9KLS88BLV
Altizide, (-)-
JI3ZO158IN
SR-05000001753
UNII-D9KLS88BLV
UNII-GI8CB72B0D
UNII-JI3ZO158IN
altozide
Prestwick_43
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Altizide; (3RS)-6-Chloro-3-[(prop-2-enylsulfanyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS-5588-16-9
Spectrum_001104
starbld0016521
SpecPlus_000833
Prestwick0_000721
Prestwick1_000721
Prestwick2_000721
Prestwick3_000721
Spectrum2_001367
Spectrum3_000902
Spectrum4_000999
Spectrum5_001725
P 1779
BSPBio_000642
KBioGR_001437
KBioSS_001584
6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide
MLS002153973
DivK1c_001031
DivK1c_006929
SCHEMBL124525
SPECTRUM1500804
SPBio_001294
SPBio_002581
BPBio1_000708
CHEMBL599870
CHEBI:91768
HMS503O03
KBio1_001031
KBio1_001873
KBio2_001584
KBio2_004152
KBio2_006720
KBio3_001844
NINDS_001031
VGLGVJVUHYTIIU-UHFFFAOYSA-N
HMS1570A04
HMS1921I12
HMS2092K18
HMS2097A04
HMS2233O21
HMS3373K04
HMS3714A04
Pharmakon1600-01500804
HY-B1254
Tox21_111347
CCG-38982
NSC757786
AKOS027381757
Tox21_111347_1
IDI1_001031
SMP1_000012
NCGC00094855-02
NCGC00094855-03
NCGC00094855-06
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1|E6,2,4-benzothiadiazine-7-sulfonamide
SMR001233310
SBI-0052594.P002
DB-052814
AB00053099
CS-0013046
NS00005608
D02838
AB00053099_08
SR-05000001753-1
SR-05000001753-3
BRD-A56675431-001-04-0
BRD-A56675431-001-07-3
BRD-A56675431-001-12-3
Altizide, European Pharmacopoeia (EP) Reference Standard
226-994-8
3-((allylthio)methyl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide
Solubility of 3-(allylsulfanylmethyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
The solubility of the compound 3-(allylsulfanylmethyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide (C11H12ClN3O4S3) can be assessed through several key points:
In summary, while specific solubility data may vary and is often influenced by factors such as pH and the presence of other ionic species, this compound is expected to have >solution in polar solvents, particularly water and alcohols due to its functional groups. Classically, "Like dissolves like," suggesting that its solubility profile is likely to favor polar environments.