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3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

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Identification
Molecular formula
C18H18BrNO2
CAS number
Not available
IUPAC name
3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
State
State

At room temperature, this compound is a solid, generally forming crystalline structures when pure. It is typically stable under normal conditions.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
403.28g/mol
Molar mass
403.2760g/mol
Density
1.4500g/cm3
Appearence

3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is typically a solid compound. The appearance might vary from white to off-white crystalline forms depending on its purity and specific form.

Comment on solubility

Solubility of 3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

The solubility of 3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol (C18H18BrNO2) is influenced by several factors, including its structural characteristics and the nature of the solvent used.

Key Points on Solubility:

  • Polarity: This compound contains various functional groups that can affect its polarity. The presence of a diol and a bromine atom can engage in hydrogen bonding, potentially enhancing solubility in polar solvents.
  • Solvent Interaction: The solubility behavior may vary greatly with solvents. For instance:
    • Highly polar solvents like water may dissolve it to a limited extent due to its hydrophobic regions.
    • Non-polar organic solvents (e.g., hexane) may not be effective due to the hydrophilic nature of the diol.
  • Temperature Effects: As with many compounds, increasing temperature generally enhances solubility. However, the specific temperature dependence for this compound requires empirical testing to fully understand its solubility profile.
  • Applications: Understanding the solubility is key, especially if this compound is intended for pharmaceutical applications, where solubility can affect bioavailability.

In summary, while the solubility of 3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol may not be straightforward, its solubility characteristics can be significantly influenced by solvents and conditions. Further experimental investigations are necessary to delineate its precise solubility in various media.

Interesting facts

Interesting Facts about 3-Allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

The compound 3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol, with its complex structure, presents an intriguing area of study for both pharmaceutical applications and organic synthesis. Here are some fascinating aspects to consider:

  • Diverse Applications: This compound belongs to the family of benzazepines, known for their biological activity, particularly in the realm of neuropharmacology. Compounds from this class have been investigated for their potential use in treating conditions like schizophrenia and Parkinson’s disease.
  • Allyl Group Importance: The presence of the allyl group not only contributes to the compound’s reactivity but also enhances its potential biological activity. This group can serve as a site for further functionalization, potentially leading to the development of more effective derivatives.
  • Intelectual Curiosity: Chemists are often fascinated by compounds with complex rings and multiple stereocenters, as they exemplify the challenges faced in synthesis and structural elucidation. This compound, featuring a tetrahydro-benzazepine framework, serves as an excellent example of such complexity.
  • Synthetic Pathways: The synthesis of this benzazepine derivative can be quite intricate, often involving multi-step reactions. Understanding these pathways is critical for chemists who aim to explore similar structures or optimize yield and selectivity.
  • Research Opportunities: The unusual characteristics of benzazepines, particularly derivatives like this one, continue to present opportunities for academic and industrial research, especially in discovering new medicinal compounds.

Overall, the study of 3-allyl-9-bromo-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol exemplifies the critical interplay between chemistry and medicinal applications. With its diverse structural features and potential functional benefits, it surely captures the attention of chemists and pharmacologists alike.

Synonyms
6-Br-Apb
135974-57-1
3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CHEMBL32145
SCHEMBL3516110
BDBM50004922
3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Br-APB)
RS-(+/-)-6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol