Skip to main content

3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

ADVERTISEMENT
Identification
Molecular formula
C19H19NO2
CAS number
1824743-84-5
IUPAC name
3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
State
State

At room temperature, the compound is typically found in a solid state. It may be supplied as a powder or crystalline solid.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
343.00
Boiling point (Kelvin)
616.15
General information
Molecular weight
325.42g/mol
Molar mass
325.4240g/mol
Density
1.2345g/cm3
Appearence

3-Allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is typically a solid compound with crystalline properties. Depending on its specific form and purity, it may appear as a white or off-white powder.

Comment on solubility

Solubility of 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

The solubility characteristics of the compound 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol (C19H19NO2) can be intriguing and provide vital insights into its potential applications and behavior in various chemical environments.

General Solubility Behavior

Understanding the solubility of this compound can be broken down into several factors:

  • Polarity: The presence of hydroxyl (–OH) groups in the diol section suggests potential for hydrophilic interactions with water, while the alkyl and phenyl groups are more hydrophobic. This combination indicates a complex solubility behavior.
  • Solvent Compatibility: This compound may demonstrate solubility in a variety of organic solvents, particularly those with moderate polarity such as ethanol, dimethyl sulfoxide (DMSO), or chloroform.
  • Temperature Effects: Like many organic compounds, its solubility could significantly increase with temperature, suggesting that heating may enhance dissolvability in certain solvents.

Insights and Implications

Given these attributes, the solubility of 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is likely to be influenced by:

  • Hydrogen Bonding: The –OH groups can engage in hydrogen bonding, which can both enhance solubility in polar solvents and decrease it in non-polar environments.
  • Structural Complexity: The intricate structure may lead to steric hindrance affecting how the compound interacts with solvents.

In summary, the solubility of C19H19NO2 is not straightforward but rather an interesting interplay of several factors that can determine its behavior in different chemical environments.

Interesting facts

Interesting Facts about 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

The compound 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is a fascinating example of a complex organic molecule with intriguing properties and potential applications in various fields.

Structural Characteristics

This compound is a member of the benzazepine family, which is known for its significant role in medicinal chemistry. Here are some key structural features:

  • Tetrahydro structure: The presence of multiple rings and the tetrahydro configuration contribute to its unique three-dimensional shape.
  • Allylic side chain: The allyl group may enhance its reactivity and interactions with biological targets.
  • Phenyl ring: This aromatic group can influence the compound's chemical properties, such as stability and electronic behavior.

Biological Significance

Compounds of this nature often exhibit various biological activities. Although specific studies may be limited, here are some general points regarding their significance:

  • Anti-cancer potential: Many benzazepines have shown promise as anti-cancer agents, targeting specific pathways involved in tumor growth.
  • Neuroactive properties: Certain derivatives can interact with neurotransmitter systems, suggesting possible applications in treating neurological disorders.
  • Pharmacophore diversity: The varied functional groups allow for modifications that can lead to the discovery of new drugs with enhanced effects.

Applications in Research

The exploration of 3-allyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol can provide insights into:

  • Synthetic methodologies: The synthesis of such complex compounds encourages the development of innovative synthetic routes.
  • Mechanistic studies: Understanding the interactions and reactions involving this compound can reveal crucial insights into reaction mechanisms.
  • Drug design: Serving as a template, it can be modified to optimize pharmacological properties for specific therapeutic areas.

Exploring compounds like this not only enriches the field of organic chemistry but also opens new avenues for drug discovery and development. As researchers continue to study such complex structures, the potential for breakthroughs in medicine and technology can be immense.

Synonyms
104422-04-0
Skf-77434
SKF 77434
SK&F 77434
3-Allyl-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
UNII-XA99M7XZR5
CHEBI:63988
3-allyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol
5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
XA99M7XZR5
1H-3-Benzazepine-7,8-diol,2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
CHEMBL288090
DTXSID3043817
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
(+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
J247.964H
(+/-)-SKF-77434
N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
1-phenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-
(+/-)-SKF 38393, N-allyl-, hydrobromide
3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
SKF-77,434
Lopac0_001143
SCHEMBL7390591
DTXCID1023817
BDBM50004918
PDSP1_001525
PDSP2_001509
CCG-205217
SDCCGSBI-0051110.P002
SKF 38393, N-allyl-, hydrobromide
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
NCGC00015915-03
NCGC00015915-04
NCGC00015915-08
NCGC00025249-02
L001232
Q7390600
BRD-A64227845-004-02-8
BRD-A64227845-004-09-3
(+)-7,8-di-hydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine
(+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride