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3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one

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Identification
Molecular formula
C8H11NO3
CAS number
72858-26-9
IUPAC name
3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one
State
State

At room temperature, 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one is in a solid state. It appears as a stable, crystalline solid under standard conditions of temperature and pressure.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
167.19g/mol
Molar mass
167.1850g/mol
Density
1.2400g/cm3
Appearence

3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one is typically characterized by a crystalline solid appearance. It may appear as beige to off-white crystals. The compound’s structure contributes to its unique appearance, often forming needle-like or prismatic crystals.

Comment on solubility

Solubility of 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one (C8H11NO3)

Understanding the solubility of 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one is crucial for its applications in various chemical and pharmaceutical processes. Given its unique structure, several factors influence its solubility behavior:

  • Polarity: The presence of hydroxyl (-OH) and carbonyl (C=O) functional groups in the compound enhances its ability to interact with polar solvents, suggesting it is likely soluble in water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the hydroxy group further increases its affinity for polar solvents, improving solubility.
  • Hydrophobic Regions: The dimethyl groups contribute to some hydrophobic characteristics, which may affect solubility in non-polar solvents.

Generally, one can expect that 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one will exhibit:

  • Good solubility in polar solvents (like water, methanol, or ethanol).
  • Poor solubility in non-polar solvents (such as hexane or benzene).

In summary, while the exact solubility depends on various factors, the combination of functional groups in this compound suggests strong solubility in polar environments, making it versatile for use in different chemical contexts.

Interesting facts

Exploring 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one

3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one is a fascinating organic compound that showcases the intricate relationship between structure and functionality in organic chemistry. This compound is particularly notable for its production and occurrence in nature, providing abundant insights into both synthetic and biological chemistry.

Key Characteristics

  • Functional Diversity: The compound features a variety of functional groups, including an acetyl group and a hydroxyl group, which contribute to its reactivity and applications in different chemical processes.
  • Biological Significance: It is known for its role in the biosynthesis of various natural products, making it an important compound in medicinal chemistry.
  • Synthetic Potential: Due to its unique structure, 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one serves as a valuable intermediate in organic synthesis and may pave the way for the development of novel pharmaceuticals.

Researchers have been captivated by its potential, often quoting that "the complexity of nature leads to the richness of organic chemistry." The exploration of compounds like 3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one not only deepens our understanding of organic synthesis but also enhances our knowledge of chemical interactions in biological systems.

Furthermore, compounds of this nature exemplify how small structural changes can lead to significant differences in biological activity, an essential concept in drug design and discovery. Therefore, studying this compound is not just about understanding its chemical properties but also about appreciating its role in the broader context of life sciences.

Synonyms
98593-79-4
3-acetyl-4,5-dimethyl-5-hydroxy-1,5-dihydro-2h-pyrrol-2-one
3-acetyl-5-hydroxy-4,5-dimethyl-1,5-dihydro-2h-pyrrol-2-one
3-Acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2(5H)-one
3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one
3-acetyl-5-hydroxy-4,5-dimethyl-2,5-dihydro-1H-pyrrol-2-one
CHEMBL340132
DHZJIJWGYQXKFT-UHFFFAOYSA-N
2H-Pyrrol-2-one,3-acetyl-1,5-dihydro-5-hydroxy-4,5-dimethyl-
MFCD00138600
AKOS015993236
DB-057737
7C-017
(5S)-3-acetyl-5-hydroxy-4,5-dimethyl-1H-pyrrol-2-one
3-Acetyl-4,5-dimethyl-5-hydroxy-1,5-dihydropyrrol-2-one