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Rapamycin

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Identification
Molecular formula
C51H79NO13
CAS number
53123-88-9
IUPAC name
[3-acetoxy-6-[formyl(methyl)amino]-1-[5-(15-hydroxy-21-methoxy-9,20-dimethyl-6,8,11,17-tetraoxo-3,18,26-trioxa-7,28,29-triazatricyclo[23.2.1.12,5]nonacosa-1(27),2(29),4,12,23,25(28)-hexaen-19-yl)-4-methoxy-3-methyl-pentyl]-2,4-dimethyl-hex-5-enyl] 2,3-dimethoxypropanoate
State
State

At room temperature, Rapamycin is a solid. Due to its complex structure and sensitivity to environmental conditions, it is typically stored under specific conditions to maintain its stability.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.15
General information
Molecular weight
914.17g/mol
Molar mass
914.1720g/mol
Density
0.9600g/cm3
Appearence

Rapamycin is a solid compound that typically appears as a white or off-white powder. It is often provided in crystalline form and is known to be sensitive to light and air, hence usually stored in light-resistant containers.

Comment on solubility

Solubility of 3-acetoxy-6-[formyl(methyl)amino]-1-[5-(15-hydroxy-21-methoxy-9,20-dimethyl-6,8,11,17-tetraoxo-3,18,26-trioxa-7,28,29-triazatricyclo[23.2.1.12,5]nonacosa-1(27),2(29),4,12,23,25(28)-hexaen-19-yl)-4-methoxy-3-methyl-pentyl]-2,4-dimethyl-hex-5-enyl] 2,3-dimethoxypropanoate

The solubility of the compound with the formula C51H79NO13 is an intriguing topic due to its complex chemical structure. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of multiple functional groups, such as acetoxy and methoxy groups, contributes to the overall polarity of the molecule, affecting its solubility.
  • Solvent Interaction: This compound is likely to exhibit solubility in polar solvents like ethanol or methanol, but may have limited solubility in non-polar solvents due to its large hydrophilic regions.
  • Hydrogen Bonding: Functional groups that can participate in hydrogen bonding could enhance solubility in polar solvents, while reducing solubility in non-polar environments.
  • Chain Length and Branching: The branched structure of the pentyl and hexenyl components may further influence its solubility by affecting how the molecule interacts with solvent molecules.
  • Concentration Effects: At higher concentrations, solubility might be impacted by the formation of aggregates or micelles, which may alter its effective solubility in solution.

In summary, understanding the solubility of this compound involves analyzing the interplay of its polar and non-polar characteristics, solvent types, and structural features. As noted, "solubility is a fundamental property that governs the behavior and reactivity of chemical compounds in various environments."

Interesting facts

Interesting Facts about 3-acetoxy-6-[formyl(methyl)amino]-1-[5-(15-hydroxy-21-methoxy-9,20-dimethyl-6,8,11,17-tetraoxo-3,18,26-trioxa-7,28,29-triazatricyclo[23.2.1.12,5]nonacosa-1(27),2(29),4,12,23,25(28)-hexaen-19-yl)-4-methoxy-3-methyl-pentyl]-2,4-dimethyl-hex-5-enyl] 2,3-dimethoxypropanoate

This compound is a *remarkable example* of a complex organic molecule that showcases the intricate dance of chemical structures in nature. Here are some fascinating aspects of it:

  • Complex Structure: The intricate architecture of this compound includes multiple functional groups, which allow it to participate in varied chemical reactions. Its complexity suggests unique properties and potential applications in medicinal chemistry.
  • Natural Derivation: Compounds like this one might be derived from natural sources, highlighting how nature can inspire synthetic routes for generating bioactive molecules. This underscores the importance of biodiversity in drug discovery.
  • Potential Applications: Given its unique structure, this compound may hold promise for multiple applications, including:
    • Pharmaceutical development, particularly in therapeutics.
    • Research in biochemistry to understand enzyme interactions.
    • Use as a molecular probe for investigating biological processes.
  • Study Opportunity: This compound presents a fertile ground for research. Scientists can investigate its reactivity and stability, contributing to the broader understanding of organic chemistry principles.
  • Quote: As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." Studying complex compounds like this can lead to breakthrough discoveries in both fundamental and applied chemistry.

In summary, 3-acetoxy-6-[formyl(methyl)amino]-1-[5-(15-hydroxy-21-methoxy-9,20-dimethyl-6,8,11,17-tetraoxo-3,18,26-trioxa-7,28,29-triazatricyclo[23.2.1.12,5]nonacosa-1(27),2(29),4,12,23,25(28)-hexaen-19-yl)-4-methoxy-3-methyl-pentyl]-2,4-dimethyl-hex-5-enyl] 2,3-dimethoxypropanoate is not just a molecular entity but a gateway to potential innovations and an invitation to delve into the depths of chemical science.