Skip to main content

Acetrizoic acid

ADVERTISEMENT
Identification
Molecular formula
C11H9I3N2O4
CAS number
28179-13-5
IUPAC name
3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
State
State

Acetrizoic acid is typically a solid at room temperature.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
613.95g/mol
Molar mass
613.9540g/mol
Density
2.4600g/cm3
Appearence

Acetrizoic acid appears as a white or nearly white crystalline powder. It is typically odorless and may have a bitter taste. The compound is often used in the form of its sodium or meglumine salts.

Comment on solubility

Solubility of 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

The solubility of 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid (C11H9I3N2O4) is influenced by its complex structure, which includes both hydrophilic and hydrophobic characteristics.

Key factors affecting its solubility are:

  • Polarity: The presence of polar functional groups, such as the acetamido and carbamoyl moieties, suggests that the compound may exhibit some degree of solubility in polar solvents.
  • Iodine Atoms: The high number of iodine atoms contributes to increased molecular weight and possible hydrophobic interactions, which might limit solubility in water.
  • pH Dependency: As a benzoic acid derivative, its solubility may also be impacted by the pH of the solution, particularly as the compound can exist in both protonated and deprotonated forms.

In summary, while 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid may exhibit moderate solubility in polar solvents, its high iodine content and acid characteristics will necessitate careful consideration of solvent choice and environmental conditions for optimal solubility.

Interesting facts

Interesting Facts About 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid is a notable compound in the realm of organic chemistry, particularly due to its extensive use in medicinal chemistry and imaging studies. Here are some intriguing aspects of this unique compound:

  • Imaging Agent: One of the most significant applications of this compound is its use as a contrast agent in medical imaging, especially in the field of radiology.
  • Iodine Content: The presence of three iodine atoms contributes to the compound's radiopaque properties, enhancing contrast in imaging procedures.
  • Biological Relevance: This compound's structure allows it to interact with biological tissues effectively, making it valuable in pharmacological studies.
  • Derivatives and Analogues: The ability to modify its amide and carboxylic acid functional groups has prompted numerous studies, leading to the development of derivatives with enhanced properties.
  • Environmental Impact: Understanding the behavior and degradation of this compound is important for assessing its environmental impact, particularly in wastewater treatment and toxicity studies.

As one scholar aptly noted, “The intricacies of chemical compounds often reflect their potential in both scientific and practical applications.” The study of 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid exemplifies this principle, showcasing the intersection of chemistry, biology, and environmental science.

Given its multifaceted roles and properties, researchers are continuously drawn to explore new avenues where this compound might create breakthroughs in medical diagnostics and therapeutic developments.

Synonyms
iotalamic acid
IOTHALAMIC ACID
2276-90-6
3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
Acidum jotalamicum
Acido iotalamico
5-Acetamido-2,4,6-triiodo-N-methylisophthalamic acid
Acide iotalamique
UNII-16CHD79MIX
EINECS 218-897-4
16CHD79MIX
MI-216
NSC-759891
Acide iotalamique [INN-French]
Acido iotalamico [INN-Spanish]
Acidum iotalamicum [INN-Latin]
Acid, Iotalamic
Iotalamic acid [INN]
Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)-
Iothalamic acid [USAN:USP]
DTXSID5023164
EC 218-897-4
NSC 759891
3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]benzoic acid
Iothalamic acid (USAN:USP)
IOTALAMIC ACID (MART.)
IOTALAMIC ACID [MART.]
Acide iotalamique (INN-French)
Acido iotalamico (INN-Spanish)
Acidum iotalamicum (INN-Latin)
IOTHALAMIC ACID (USP-RS)
IOTHALAMIC ACID [USP-RS]
Iothalamic acid [USAN]
IOTALAMIC ACID (EP IMPURITY)
IOTALAMIC ACID [EP IMPURITY]
BENZOIC ACID, 3-(ACETYLAMINO)-2,4,6-TRIIODO-5-((METHYLAMINO)CARBONYL
Acid, Iothalamic
Acid, Methalamic
Acidum iotalamicum
IOTHALAMIC ACID (USP MONOGRAPH)
IOTHALAMIC ACID [USP MONOGRAPH]
MI 216
iothalamic-acid-d3
Benzoic acid,3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]-
Iothalamic acid (USP)
Iotalamic acid (Standard)
IOTHALAMATE [VANDF]
SCHEMBL38419
IOTALAMIC ACID [JAN]
IOTHALAMIC ACID [MI]
Iotalamic acid (JP17/INN)
DTXCID903164
CHEMBL1201300
IOTALAMIC ACID [WHO-DD]
SCHEMBL23630220
CHEBI:31713
HY-B1053R
HMS3264D13
Pharmakon1600-01503836
BCP13316
DMB62331
HY-B1053
NSC759891
AKOS025402283
AC-7611
CCG-213208
CS-4575
DB09133
NCGC00183042-01
MS-30726
NS00004121
D01258
AB01563288_01
EN300-18564825
SR-01000944232
Q6064129
SR-01000944232-1
BRD-K98250023-001-01-0
1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamate