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Sialic acid

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Identification
Molecular formula
C11H19NO9
CAS number
131-48-6
IUPAC name
3-acetamido-2-(3-amino-1,2-dihydroxy-propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
State
State

At room temperature, sialic acid is typically found as a solid. It is often stored as a powder or a concentrated solution for use in biochemical research.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.00
Boiling point (Celsius)
467.00
Boiling point (Kelvin)
740.00
General information
Molecular weight
309.27g/mol
Molar mass
309.2690g/mol
Density
1.5900g/cm3
Appearence

Sialic acid is typically a white crystalline powder when isolated in its pure form. It is hygroscopic and may appear as a sticky or viscous solid if exposed to atmospheric moisture.

Comment on solubility

Solubility of 3-acetamido-2-(3-amino-1,2-dihydroxy-propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid

The solubility of 3-acetamido-2-(3-amino-1,2-dihydroxy-propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid, with the chemical formula C11H19NO9, is an important consideration for its applications. Understanding the solubility can provide insights into its behavior in various environments and its potential for biological activity.

Here are some key aspects of its solubility:

  • Polar Functional Groups: The presence of multiple hydroxyl groups (-OH) and a carboxylic acid functional group (-COOH) suggest a tendency towards high solubility in polar solvents, such as water.
  • Hydrogen Bonding: These -OH and -COOH groups can form extensive hydrogen bonds with water molecules, which typically leads to increased solubility.
  • Amide Group Impact: The acetamido (-NHCOCH3) group may further enhance solubility due to its polar nature, suggesting good solubility in water.

As a result, we can consider that this compound is likely to exhibit:

  • High Solubility: In polar solvents, especially in aqueous solutions.
  • Limited Solubility: In non-polar solvents due to its polar character.

In summary, the solubility profile of this compound is quite favorable for interactions in biological systems, and its extensive polar functional groups support a high degree of solubility in aqueous environments. This characteristic could play a significant role in its physical properties and applications in pharmaceutical formulations.

Interesting facts

Interesting Facts about 3-acetamido-2-(3-amino-1,2-dihydroxy-propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid

This compound represents a fascinating integration of functional groups that form a complex structure, indicative of its potential biochemical activities. Here are some compelling aspects to consider:

  • Natural Product Inspiration: This compound could relate to naturally occurring molecules, particularly those found in various biochemical pathways that involve carbohydrates and amino acids.
  • Pharmaceutical Potential: Given its structure, there is the possibility that this compound could be investigated for therapeutic uses, particularly for its implications in modulating metabolic pathways.
  • Hydroxy Groups: The presence of multiple hydroxy (-OH) groups can suggest increased reactivity and solubility, which can affect how this molecule interacts with biological systems.
  • Carboxylic Acid Functionality: The carboxylic acid moiety can play a key role in acid-base chemistry, potentially making this compound useful in biochemical buffers.
  • Enzymatic Interactions: The intricate structure may allow it to serve as a substrate or inhibitor in various enzymatic reactions, providing avenues for research in enzymology.

As a scientist or chemist studying such compounds, the emphasis on understanding how these structural features translate to biological activity can motivate research into new drugs or therapies. The exploration of potential modifications to enhance the efficacy or reduce the toxicity of this molecule represents a thrilling avenue of inquiry.

In conclusion, studying 3-acetamido-2-(3-amino-1,2-dihydroxy-propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid could open up new doors in both fundamental research and practical applications in medicine and biotechnology. It serves as a prime example of how chemical diversity can lead to innovative discoveries in science.

Synonyms
SCHEMBL21126049
PD039861