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Amitriptyline

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Identification
Molecular formula
C20H23N
CAS number
50-48-6
IUPAC name
3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine
State
State

In its pure form, amitriptyline is a solid at room temperature.

Melting point (Celsius)
196.50
Melting point (Kelvin)
469.65
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
277.40g/mol
Molar mass
277.4040g/mol
Density
1.0730g/cm3
Appearence

Amitriptyline appears as a white to off-white crystalline powder. It can be in solid form as a powder or may be processed into tablet form for medications.

Comment on solubility

Solubility of 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine

The solubility of the compound 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine (C20H23N) is influenced by its unique structural attributes. Understanding its solubility behavior is crucial for applications in pharmaceuticals and material science. Here are some pertinent details:

  • Polarity: This compound contains both aromatic and non-aromatic structures which can affect its polarity.
  • Solvent Compatibility: Typically, such compounds demonstrate greater solubility in organic solvents like methanol, ethanol, or dimethyl sulfoxide (DMSO) rather than in water.
  • Temperature Effects: As is common with organic compounds, an increase in temperature might enhance solubility due to greater kinetic energy.

In general, compounds featuring aromatic rings tend to have reduced solubility in polar solvents, thus illustrating the importance of solvent selection in experimental procedures. As a result, it is often stated that "the nature of the solvent profoundly influences solubility." Consequently, careful consideration of solubility can lead to more effective applications and enhanced efficacy in various fields.

Interesting facts

Interesting Facts about 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine

This intriguing compound is part of a class of molecules known for their potential therapeutic applications. Here are some engaging aspects of this compound:

  • Chemical Structure: The structure of 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine features a unique arrangement of atoms, combining a benzothiepin moiety with a dimethylamino group. This diversified structure may contribute to its biological activity.
  • Potential Applications: Compounds in this category have garnered attention for their *possible usage in pharmaceuticals*, especially in treating neurological disorders or exhibiting anti-depressant effects. Research continues to explore the efficacy of such compounds in medicinal chemistry.
  • Mechanistic Insights: Understanding how this compound behaves at the molecular level can unlock paths to new treatments. Its interaction with receptors in the brain could illustrate how such structures influence *mood or cognitive functions*.
  • Synthetic Routes: The synthesis of this compound can involve interesting chemical reactions that showcase the bridge between theoretical and practical chemistry. By developing innovative synthetic methods, chemists can optimize yield and reduce environmental impact.
  • Research Frontiers: The curiosity surrounding this compound pushes researchers to conduct studies focusing on its biological properties, exploring both *in vitro* and *in vivo* results. Each study adds a layer to our understanding of its potential benefits and risks.

As outlined, 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine is more than just a complex name; it represents a gateway to explore significant avenues in science that could enhance our comprehension of drug development and therapeutic interventions.

Synonyms
Dosulepin
113-53-1
Prestwick0_000488
Prestwick1_000488
Oprea1_493999
SPBio_002276
(E,Z)-3-(dibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine
DTXSID2022961
AKOS030239801
NS00099823
11-(3-Dimethylaminopropyliden)-6,11-dihydrodibenz-(b,e)thiepin