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FAMPA (Fluorescent Amino Acid)

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Identification
Molecular formula
C18H15NO3
CAS number
924283-74-7
IUPAC name
3-(4,5-diphenyloxazol-2-yl)propanoic acid
State
State
3-(4,5-diphenyloxazol-2-yl)propanoic acid is a solid at room temperature.
Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
285.31g/mol
Molar mass
285.3080g/mol
Density
1.3100g/cm3
Appearence

3-(4,5-diphenyloxazol-2-yl)propanoic acid typically appears as a white crystalline powder. It is known for its high purity and is often used in fluorescent studies and labeling.

Comment on solubility

Solubility of 3-(4,5-diphenyloxazol-2-yl)propanoic acid (C18H15NO3)

The solubility of 3-(4,5-diphenyloxazol-2-yl)propanoic acid can be intriguing due to its unique structure. This compound exhibits properties that can influence its dissolution behavior in various solvents. Here are some key points regarding its solubility:

  • Polar vs. Non-polar Solvents: The presence of polar functional groups in the molecule suggests that it may show a greater tendency to dissolve in polar solvents such as water or methanol, although its hydrophobic phenyl groups could hinder complete solubility.
  • Temperature Dependence: Like many organic compounds, the solubility of this acid is likely to increase with temperature. As kinetic energy increases, solute-solvent interactions become more favorable, allowing more molecules to dissolve.
  • pH Sensitivity: The presence of the carboxylic acid group may affect solubility through ionization. In more alkaline conditions, the acid can deprotonate, leading to increased solubility due to the formation of charged species.
  • Concentration Effects: The degree of solubility may also depend on the concentration of the compound in solution; at higher concentrations, solubility may plateau or lead to precipitation.

In summary, while 3-(4,5-diphenyloxazol-2-yl)propanoic acid is likely soluble in polar solvents and its solubility can be influenced by factors such as temperature, pH, and concentration, the precise behavior may require experimental data for confirmation. Understanding these aspects will be critical for practical applications involving this compound.

Interesting facts

Interesting Facts about 3-(4,5-diphenyloxazol-2-yl)propanoic Acid

3-(4,5-diphenyloxazol-2-yl)propanoic acid is a fascinating compound that has garnered attention in various fields due to its unique structural features and potential applications. Here are some noteworthy points about this intriguing molecule:

  • Structural Complexity: This compound contains a central propanoic acid moiety flanked by a diphenyloxazole group. The presence of the oxazole ring contributes to its relative stability and functional reactivity, making it an interesting candidate for research.
  • Potential Applications: Compounds like this are often explored for their roles in organic synthesis, drug development, and fluorescent probes. Their unique properties can lead to advancements in materials science and medicinal chemistry.
  • Spectroscopy Insights: Due to its diverse structure, this compound can showcase exquisite characteristics in various spectroscopic techniques. For instance, it can be effectively studied through NMR (Nuclear Magnetic Resonance) and IR (Infrared Spectroscopy) to understand its conformational preferences.
  • Biological Significance: Investigations into analogs of this compound have suggested potential biological activities, which could be key in developing new therapeutic agents. This is particularly exciting for chemists interested in the interface of organic chemistry and biology.
  • Research Community: The compound serves as an important building block in various synthetic pathways, making it a staple in research labs focused on novel compound synthesis and material development.

As quoted by a seasoned researcher, "The beauty of organic chemistry lies in the diversity of its compounds and the endless possibilities they present for innovation." This sentiment is certainly applicable to 3-(4,5-diphenyloxazol-2-yl)propanoic acid, showcasing the remarkable journey of science that always leads us to new discoveries.

Synonyms
oxaprozin
21256-18-8
Daypro
3-(4,5-Diphenyloxazol-2-yl)propanoic acid
3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
Alvo
Oxaprozine
Oxaprozinum
Deflam
Oxaprozina
Voir
4,5-Diphenyl-2-oxazolepropionic acid
WY-21743
4,5-Diphenyl-2-oxazolepropanoic acid
WY-21,743
2-Oxazolepropanoic acid, 4,5-diphenyl-
Oxaprozine [INN-French]
Oxaprozinum [INN-Latin]
Oxaprozina [INN-Spanish]
WY 21743
MFCD00215977
NSC310839
Duraprost
Duraprox
Oxapro
Oxaprozinum;Wy21743
NSC-310839
Walix
MHJ80W9LRB
3-(4,5-Diphenyl-2-oxazolyl)propenoic acid
3-(diphenyl-1,3-oxazol-2-yl)propanoic acid
beta-(4,5-Diphenyloxazol-2-yl)propionic acid
NSC 310839
CHEBI:7822
EINECS 244-296-1
UNII-MHJ80W9LRB
BRN 1083168
CHEMBL1071
DTXSID1045118
HSDB 7586
2-OXAZOLEPROPIONIC ACID, 4,5-DIPHENYL-
.beta.-(4,5-Diphenyloxazol-2-yl)propionic acid
Danoprox
Dayrun
CAS-21256-18-8
Oxaprozine (INN-French)
Oxaprozinum (INN-Latin)
Oxaprozina (INN-Spanish)
OXAPROZIN (MART.)
OXAPROZIN [MART.]
OXAPROZIN (USP-RS)
OXAPROZIN [USP-RS]
DTXCID9025118
OXAPROZIN (USP MONOGRAPH)
OXAPROZIN [USP MONOGRAPH]
Actirin
Xopane
Oxaprozin (USAN:USP:INN:BAN:JAN)
Oxaprozin [USAN:USP:INN:BAN:JAN]
SMR000058286
Daypro (TN)
SR-01000076053
oxaprosin
Durapro
Oxaprozi
Oxaprozin, solid
Oxaprozin,(S)
4,5-Diphenyl-2-oxazolepropanoic acid;4,5-Diphenyl-2-oxazolepropionic acid;3-(4,5-Diphenyloxazol-2-yl)propionic acid
NCI310839
COXANTO
Oxaprozin (Standard)
4,5 Diphenyl 2 oxazolepropionic Acid
4, 5-Diphenyl-2-oxazolepropionic acid
OXAPROZIN [INN]
OXAPROZIN [JAN]
OXAPROZIN [MI]
OXAPROZIN [HSDB]
OXAPROZIN [USAN]
Maybridge1_008800
Prestwick0_001060
Prestwick1_001060
Prestwick2_001060
Prestwick3_001060
Spectrum2_001696
Spectrum3_001078
Spectrum4_001231
Lopac-O-9637
OXAPROZIN [VANDF]
O 9637
OXAPROZIN [WHO-DD]
SCHEMBL3286
NCIStruc1_000799
NCIStruc2_000787
BIDD:PXR0149
Lopac0_000944
Oprea1_509470
BSPBio_001020
BSPBio_002696
KBioGR_001722
MLS000759535
MLS001424072
BIDD:GT0438
SPECTRUM1505267
Oxaprozin - Bio-X trade mark
SPBio_001652
SPBio_002940
Oxaprozin (JP18/USP/INN)
BPBio1_001122
GTPL7252
OXAPROZIN [ORANGE BOOK]
HMS566H22
HY-B0808R
KBio3_001916
M01AE12
HMS1571C22
HMS1922P17
HMS2051L15
HMS2093O08
HMS2098C22
HMS3262N10
HMS3393L15
HMS3652H17
HMS3715C22
HMS3885L11
Pharmakon1600-01505267
Wy21743
BCP28431
HY-B0808
Tox21_110059
Tox21_500944
2-Oxazolepropanoic acid,5-diphenyl-
2-Oxazolepropionic acid,5-diphenyl-
BDBM50002861
CCG-36508
NCGC00014711
NSC758949
s4230
4,5-diphenyloxazole-2-propanoic acid
AKOS000206807
Tox21_110059_1
1ST7199
CS-7975
DB00991
FO26614
KS-5196
LP00944
NC00214
NSC-758949
SDCCGSBI-0050918.P004
NCGC00014711-01
NCGC00014711-02
NCGC00014711-03
NCGC00014711-04
NCGC00014711-05
NCGC00014711-06
NCGC00014711-07
NCGC00014711-08
NCGC00014711-09
NCGC00014711-10
NCGC00014711-11
NCGC00014711-14
NCGC00014711-15
NCGC00094249-01
NCGC00094249-02
NCGC00094249-03
NCGC00094249-04
NCGC00094249-05
NCGC00094249-06
NCGC00094249-07
NCGC00261629-01
Oxaprozin 100 microg/mL in Acetonitrile
AC-26512
BO164184
NCI60_002681
SY050819
SBI-0050918.P002
3-(4,5-Diphenyl-2-oxazolyl)propanoic acid
3-(4,5-Diphenyl-2-oxazolyl)propionic acid
AB00514024
EU-0100944
NS00008254
O0377
SW197319-4
3-(4, 5-Diphenyl-2-oxazolyl)propenoic acid
EN300-25629
3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid
C07356
D00463
AB00514024_08
AB00514024_09
Q1749609
SR-01000076053-1
SR-01000076053-3
SR-01000076053-7
SR-01000076053-9
3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid #
BRD-K25394294-001-05-7
BRD-K25394294-001-08-1
BRD-K25394294-001-13-1
BRD-K25394294-001-14-9
Z212055564
Oxaprozin, United States Pharmacopeia (USP) Reference Standard
244-296-1
BJ6