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Ferulic acid

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Identification
Molecular formula
C10H10O4
CAS number
1135-24-6
IUPAC name
3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid
State
State

At room temperature, ferulic acid is a solid. It is commonly available in its pure form as a crystalline powder and is stable under standard conditions when properly stored.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
194.18g/mol
Molar mass
194.1840g/mol
Density
1.4780g/cm3
Appearence

Ferulic acid appears as a white to pale yellow crystalline powder. It is often characterized by its crystalline nature and can be quite reflective under light. The compound is stable under normal conditions but should be protected from excessive heat and moisture.

Comment on solubility

Solubility of 3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid (C10H10O4)

3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid, often referred to as a derivative of phenolic compounds, exhibits noteworthy solubility characteristics:

  • Solvent Dependence: This compound is generally soluble in polar organic solvents such as ethanol and methanol, owing to the presence of hydroxyl and methoxy groups.
  • Aqueous Solubility: While its solubility in water is limited, the introduction of substituents like hydroxyl (-OH) does enhance potential interactions with water molecules, allowing for some degree of solubility.
  • pH Influence: The solubility may increase under alkaline conditions due to ionization; a higher pH could convert the carboxylic acid group into its anionic form, enhancing its solubility in aqueous media.

In summary, the solubility of C10H10O4 is significantly influenced by the solvent used and the surrounding environmental conditions. As stated, "the interaction of functional groups within the compound plays a crucial role in determining solubility," making it a fascinating compound for solubility studies.

Interesting facts

Interesting Facts about 3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid

3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid, commonly known as caffeic acid, is a phenolic compound that naturally occurs in various plant species. This compound has garnered significant attention in scientific research due to its wide range of biological activities.

Health Benefits

Caffeic acid is renowned for its potential health benefits, which include:

  • Antioxidant Properties: It effectively scavenges free radicals, protecting cells from oxidative stress.
  • Anti-inflammatory Effects: Studies have shown that caffeic acid helps reduce inflammation, making it beneficial for inflammatory conditions.
  • Neuroprotective Effects: Research suggests that it may help safeguard neuronal cells, presenting potential therapeutic effects against neurodegenerative diseases.

Sources

This compound is commonly found in a variety of food sources, notably:

  • Coffee: One of the richest sources of caffeic acid, contributing to the beverage's health benefits.
  • Fruits and Vegetables: Present in apples, carrots, and various herbs.
  • Herbs: Particularly rich in spices like oregano and rosemary.

Applications in Research

In the field of research, caffeic acid is being explored for various applications:

  • Pharmacology: Due to its biological activities, it holds potential in drug development.
  • Agriculture: Investigated for its use as a natural herbicide and growth promoter.
  • Cosmetics: Its antioxidant properties make it a valuable ingredient in skincare products.

Interestingly, caffeic acid is also utilized in the synthesis of other useful compounds, showcasing its importance in both natural and synthetic chemistry. As a chemist or student, understanding the multifaceted roles of caffeic acid can inspire innovative solutions in health, agriculture, and more. The exploration of such compounds highlights the intricate relationship between chemistry and biology in the development of holistic health approaches.

Synonyms
(E/Z)-ferulic acid
DTXSID5040673
Spectrum_001256
SpecPlus_000547
Spectrum2_001394
Spectrum3_001434
Spectrum4_001897
KBioGR_002459
KBioSS_001736
DivK1c_006643
SPBio_001408
CHEMBL3185646
KBio1_001587
KBio2_001736
KBio2_004304
KBio2_006872
KBio3_002388
3-methoxy4-hydroxy cinnamic acid
4-hydroxyl-3-methoxycinnamic acid
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2Z)-
3-methoxy-4-hydroxy cinnamic acid
3-methoxy-4-hydroxy-cinnamic acid
4-hydroxy-3-methoxy-cinnamic acid
HMS3655P22
AKOS028109905
NCGC00094889-05
NCI60_002312
SY013625
DB-120370
3-(4-hydroxy-3-methoxyphenyl)-acrylic acid
NS00006133
3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid
(E/Z)-Ferulic acid 1000 microg/mL in Acetone
3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid
3- (4-hydroxy-3-methoxyphenyl) -2-propenoic acid
ferulic acid (trans-4-hydroxy-3-methoxycinnamic acid)
Q51617501