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Clopidol

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Identification
Molecular formula
C11H11ClNO3
CAS number
2204-23-7
IUPAC name
[3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate
State
State

At room temperature, clopidol is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
351.50
Boiling point (Kelvin)
624.65
General information
Molecular weight
218.67g/mol
Molar mass
218.6210g/mol
Density
1.3000g/cm3
Appearence

Clopidol is typically a white crystalline powder, although it can appear slightly off-white. It is essentially odorless and has a crystalline texture.

Comment on solubility

Solubility of [3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate

The solubility of [3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate (C11H11ClNO3) can be influenced by several factors, making it a compound of interest in various chemical applications. Understanding its solubility characteristics is crucial for effective utilization in formulations.

Key Factors Affecting Solubility

  • Polarity: The presence of polar functional groups such as hydroxyl (-OH) and carbamate (-NHC(=O)O-) contributes to potential interactions with polar solvents, enhancing solubility in water and other polar media.
  • Hydrogen Bonding: The ability of [3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate to form hydrogen bonds can lead to greater solubility in aqueous solutions.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution under elevated conditions.

General Insights

In general:

  • The compound may exhibit moderate solubility in water due to its polar functional groups.
  • Solubility in organic solvents might vary; non-polar solvents may see decreased solubility.
  • Factors such as the pH of the solution can also influence solubility by affecting the ionization of the functional groups.

Overall, while [3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate shows potential for solubility in polar environments, specific empirical data should be obtained to accurately evaluate its behavior in various solvents.

Interesting facts

Interesting Facts about [3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate

[3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate is a unique compound with several intriguing characteristics that make it a subject of interest in chemistry and related fields. Below are some compelling points:

  • Functional Diversity: The compound contains multiple functional groups, including a carbamate and a chlorophenoxy group, showcasing the potential for diverse chemical reactivity and interaction.
  • Potential Applications: As a carbamate, this compound may have applications in the formulation of pesticides or pharmaceuticals. Compounds of this class often exhibit biological activity, making them valuable in agri-chemical and medicinal research.
  • Chlorine Substitution: The presence of the chlorine atom on the phenoxy ring plays a crucial role in enhancing the compound's lipophilicity, potentially affecting its biological effectiveness and absorption properties.
  • Hydroxyl Group Influence: The hydroxyl group on the propyl chain may contribute to increased solubility in polar solvents, potentially broadening its applications in various formulations.
  • Synthetic Pathways: The synthesis of this compound often involves multistep reactions, which not only highlights the creativity required in organic synthesis but also the importance of optimizing conditions to achieve desired yields.

As research on this compound and its derivatives continues, our understanding of its properties and potential applications may evolve, leading to innovative uses in various scientific fields. In the words of a renowned chemist, "The beauty of chemistry lies in its ability to transform the simplest of structures into complex, functional entities." This compound exemplifies that beauty in its intricate design and functionality.

Synonyms
CHLORPHENESIN CARBAMATE
886-74-8
Maolate
Rinlaxer
3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate
Kolpicortin-sine
3-(p-Chlorophenoxy)-1,2-propanediol 1-carbamate
3-(p-Chlorophenoxy)-2-hydroxypropyl carbamate
Chlorphensin carbamate
3-(4-Chlorophenoxy)-1,2-propanediol-1-carbamate
U-19,646
1,2-Propanediol, 3-(4-chlorophenoxy)-, 1-carbamate
CHLORPHENESINCARBAMATE
NSC 82943
Carbamic acid, 3-(p-chlorophenoxy)-2-hydroxypropyl ester
HSDB 3031
3-(p-Chlorophenoxy)-1,2-propanediol-1-carbamate
U 19646
1,2-Propanediol,3-(4-chlorophenoxy)-, 1-carbamate
1,2-Propanediol, 3-(p-chlorophenoxy)-, 1-carbamate
EINECS 212-954-7
UNII-57U5YI11WP
NSC-82943
[3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate
BRN 1978575
57U5YI11WP
CHEBI:3643
DTXSID5022803
carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester
NSC82943
HQC4WI89YG
1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate
DTXCID002803
Chlorphenesin carbamate, (-)-
U-19646
(3-p-Chlorophenoxy)-2-hydroxypropylcarbamate
1,2-Propanediol, 3-(4-chlorophenoxy)-, 1-carbamate, (-)-
Maolate; NSC 82943; Rhnesicn; Rinlaxer; U 19646; U-19,646
CHLORPHENESIN CARBAMATE (MART.)
CHLORPHENESIN CARBAMATE [MART.]
126632-50-6
Chlorphenesin carbamate [USAN:JAN]
NCGC00016548-01
CAS-886-74-8
Prestwick_882
Maolate (TN)
Prestwick0_000234
Prestwick1_000234
Prestwick2_000234
Prestwick3_000234
UNII-HQC4WI89YG
WLN: ZVO1YQ1OR DG
SCHEMBL34492
BSPBio_000307
MLS002154243
SPBio_002228
BPBio1_000339
CHEMBL607710
G014XC07GH
GLXC-26272
HMS1568P09
HMS2095P09
HMS2232O23
HMS3371A08
HMS3712P09
Maolate Tablets, Maolate Veterinary
CHLORPHENESIN CARBAMATE [MI]
Tox21_110487
CHLORPHENESIN CARBAMATE [JAN]
CHLORPHENESIN CARBAMATE [HSDB]
CHLORPHENESIN CARBAMATE [USAN]
AKOS040744828
Chlorphenesin carbamate (JP18/USAN)
CCG-220234
CHLORPHENESIN CARBAMATE [VANDF]
CHLORPHENESIN CARBAMATE, (+)-
DB14656
CHLORPHENESIN CARBAMATE [WHO-DD]
1, 3-(p-chlorophenoxy)-, 1-carbamate
NCGC00179607-01
NCGC00179607-03
1, 3-(4-chlorophenoxy)-, 1-carbamate
FC177233
SMR001233511
CHLORPHENESIN CARBAMATE [GREEN BOOK]
DB-057097
HY-107944
CHLORPHENESIN CARBAMATE [ORANGE BOOK]
CS-0030953
NS00039287
C07930
D00770
[3-(4-chlorophenoxy)-2-hydroxy-propyl] carbamate
EN300-23982086
SR-01000841824
3-[(4-chlorophenyl)oxy]-2-hydroxypropyl carbamate
SR-01000841824-2
(2RS)-3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate
BRD-A39230911-001-03-7
BRD-A39230911-001-10-2
Q27106156
1,2-PROPANEDIOL, 3-(4-CHLOROPHENOXY)-, 1-CARBAMATE, (+)-
212-954-7
3-(p-Chlorophenoxy)-1-carbamate; 3-(4-Chlorophenoxy)-2-hydroxypropylcarbamate; 3-(p-Chlorophenoxy)-1,2-propanediol-1-carbamate