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Hoechst 33258

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Identification
Molecular formula
C25H30N6O3
CAS number
23491-45-4
IUPAC name
3-[4-[6-[2-[4-[3-(dimethylamino)propoxy]phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazol-2-yl]phenoxy]-N,N-dimethyl-propan-1-amine
State
State

At room temperature, Hoechst 33258 exists as a solid compound. It is typically found in the form of a powder.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
533.63g/mol
Molar mass
533.6340g/mol
Density
0.0000g/cm3
Appearence

Hoechst 33258 is a white to off-white crystalline powder. It does not exhibit any distinctive color in its pure solid form and is often used for its fluorescent properties.

Comment on solubility

Solubility of 3-[4-[6-[2-[4-[3-(dimethylamino)propoxy]phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazol-2-yl]phenoxy]-N,N-dimethyl-propan-1-amine

The compound with the formula C25H30N6O3 presents an intriguing profile regarding its solubility characteristics. Solubility can be influenced by various factors, such as:

  • Polarity: The presence of multiple polar functional groups in the structure promotes solubility in polar solvents.
  • Molecular Size: As the molecular weight increases, solubility in water may decrease, while solubility in organic solvents may increase.
  • pH Levels: The ionization state of the amine and benzimidazole moieties can significantly affect solubility. Changes in pH can lead to enhanced solubility by increasing the ionized species.

According to various studies, compounds similar in structure may exhibit:

  1. Good solubility in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.
  2. Limited aqueous solubility at physiological pH, potentially resulting in challenges for formulation in biological contexts.

As a concluding thought, exploring the solubility of this compound not only provides insights into its potential applications but also guides its formulation for medicinal use. It is essential to consider each of these factors to maximize the effectiveness of the compound in practical applications.

Interesting facts

Interesting Facts about 3-[4-[6-[2-[4-[3-(dimethylamino)propoxy]phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazol-2-yl]phenoxy]-N,N-dimethyl-propan-1-amine

This complex compound, part of a broader class of organic molecules, exhibits intriguing properties that catch the attention of scientists in various fields. Not only does it feature multiple functional groups, including amines and ethers, but its structural composition includes multiple benzimidazole moieties, which are known for their biological activity.

Key Highlights:

  • Medicinal Significance: Compounds with a benzimidazole backbone have been widely studied for their potential in pharmaceuticals, particularly as anti-parasitic and anti-cancer agents.
  • Versatile Structure: The intricate arrangement of phenol and heterocyclic rings can lead to varied interactions in biological systems, making this compound a subject of interest in drug design.
  • Dimethylamino Group: The presence of dimethylamino groups often enhances the solubility of organic compounds in biological environments, potentially increasing their efficacy.

Furthermore, the synthesis of such compounds can involve diverse methodologies, often allowing for modifications that enhance desired properties while minimizing side effects. As noted in literature, “The exploration of complex organic compounds leads to significant advancements in medical chemistry.” This illustrates the crucial role of compounds like this in paving the way for future discoveries.

In conclusion, the multifaceted nature of 3-[4-[6-[2-[4-[3-(dimethylamino)propoxy]phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazol-2-yl]phenoxy]-N,N-dimethyl-propan-1-amine serves as a reminder of how intricately connected chemistry is with advancements in health sciences.

Synonyms
[3-(4-{2'-[4-(3-dimethylamino-propoxy)-phenyl]-3h,3'h-[5,5']bibenzoimidazolyl-2-yl}-phenoxy)-propyl]-dimethyl-amine
E97
CHEMBL34618
SCHEMBL21017825
Q27459870
3,3'-[1H,3'H-5,5'-bibenzimidazole-2,2'-diylbis(benzene-4,1-diyloxy)]bis(N,N-dimethylpropan-1-amine)