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Tranexamic acid

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Identification
Molecular formula
C8H15NO2
CAS number
1197-18-8
IUPAC name
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid
State
State

At room temperature, Tranexamic acid is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
418.00
Melting point (Kelvin)
691.15
Boiling point (Celsius)
348.30
Boiling point (Kelvin)
621.45
General information
Molecular weight
157.21g/mol
Molar mass
157.2100g/mol
Density
1.4300g/cm3
Appearence

Tranexamic acid appears as a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic Acid

The solubility of 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid, with the chemical formula C8H15NO2, can be considered under a few key factors:

  • Polarity: This compound contains both hydrophilic (polar) and hydrophobic (non-polar) characteristics. The presence of the aminomethyl group suggests that it may have some degree of solubility in polar solvents, especially in water.
  • Functional Groups: The carboxylic acid functional group typically enhances solubility in aqueous environments due to its ability to ionize and form hydrogen bonds with water molecules.
  • Hydrogen Bonding: The presence of the oxygen atom in the carbonyl and ether-like structures can contribute significantly to solubility through hydrogen bonding with solvent molecules.
  • Chain Length: The cyclohexane structure may introduce steric hindrance, which could affect the overall solubility, making it less favorable in non-polar solvents.

In summary, while this compound is likely to show good solubility in polar solvents due to the hydrophilic carboxylic acid and amino groups, its solubility in non-polar solvents may be limited. Understanding these solubility properties is essential for its application in various fields, including pharmaceuticals and materials science. As always, it's best to consult empirical data for precise solubility metrics.

Interesting facts

Interesting Facts about 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid

3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid, often referred to within the scientific community for its complex structure and potential applications, has captured the interest of many chemists. Here are some notable points about this intriguing compound:

  • Potential Medical Applications: Due to the presence of the aminomethyl group, this compound could potentially be important in medicinal chemistry. Functional groups like these are often pivotal in drug discovery and design, as they can enhance biological activity.
  • Structural Complexity: The compound contains a cyclohexane ring which adds to its structural complexity. Cyclohexane derivatives can exhibit unique physical and chemical properties, making them useful for various synthetic applications.
  • Carbonyl Functionality: The presence of the carbonyl (C=O) group introduces reactivity, allowing for various chemical transformations. This functionality is essential in many biochemical processes.
  • Bioconjugation Potential: The compound might serve as a useful tool for bioconjugation processes, where it can attach to biomolecules, enhancing their properties or facilitating their delivery in therapeutic contexts.
  • Analog Studies: Due to its detailed architecture, this compound could serve as an analog in studies aiming to understand the structure-activity relationship (SAR) of similar molecules, providing insights into optimizing biological efficacy.

As the field of synthetic organic chemistry progresses, compounds like 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid are pivotal in addressing challenges in drug development and materials science. Its intriguing structure offers a playground for chemists to explore and innovate!

Synonyms
Cetraxate
34675-84-8
Cetraxate [INN]
Cetraxato
3-(4-((trans-4-(Aminomethyl)cyclohexanecarbonyl)oxy)phenyl)propanoic acid
5VPA8CPF0N
p-hydroxyhydrocinnamic acid trans-(4-aminomethyl)cyclohexanecarboxylate
trans-4-(((4-(Aminomethyl)cyclohexyl)carbonyl)oxy)benzenepropanoic acid
CHEBI:17340
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid
Cetraxate (INN)
3-[4-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}oxy)phenyl]propanoic acid
Benzenepropanoic acid, 4-(((4-(aminomethyl)cyclohexyl)carbonyl)oxy)-, trans-
4-(2-carboxyethyl)phenyl-trans-4-aminomethylcyclohexane carboxylate hydrochloride
Cetraxatum
Cetraxatum [INN-Latin]
MLS001401399
Cetraxato [INN-Spanish]
3-[4-({[(1r,4r)-4-(aminomethyl)cyclohexyl]carbonyl}oxy)phenyl]propanoic acid
NCGC00164584-01
SMR000469197
UNII-5VPA8CPF0N
BRN 2820321
CETRAXATE [JAN]
CETRAXATE [MI]
3-(4-(trans-4-(Aminomethyl)cyclohexylcarbonyl)phenyl)propiosaeure
Hydrocinnamic acid, p-hydroxy-, 4-(aminomethyl)cyclohexanecarboxylate, trans-
CETRAXATE [WHO-DD]
SCHEMBL19437
cid_34001
SCHEMBL476429
SCHEMBL7616457
CHEMBL1187445
CHEMBL2448182
DTXSID2040658
BDBM66826
CHEBI:94638
DTXSID60860400
FHRSHSOEWXUORL-HDJSIYSDSA-N
Cetraxate HCl - Bio-X trade mark
NCGC00164584-02
BC164299
DB-048671
HY-135759
CS-0113945
C01564
D07663
AB00698546-07
Q5065694
3-[4-[[4-(aminomethyl)cyclohexyl]-oxomethoxy]phenyl]propanoic acid
3-(4-{[4-(Aminomethyl)cyclohexane-1-carbonyl]oxy}phenyl)propanoic acid
3-[4-[[4-(aminomethyl)cyclohexyl]-oxomethoxy]phenyl]propanoic acid;hydrochloride
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propionic acid;hydrochloride
3-[4-[4-(aminomethyl)cyclohexyl]carbonyloxyphenyl]propanoic acid;hydrochloride
BENZENEPROPANOIC ACID, 4-(((TRANS-4-(AMINOMETHYL)CYCLOHEXYL)CARBONYL)OXY)-
P-HYDROXYHYDROCINNAMIC ACID TRANS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLATE