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Trimethobenzamide

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Identification
Molecular formula
C24H34N2O8
CAS number
138-56-7
IUPAC name
3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate
State
State

At room temperature, trimethobenzamide is in a solid state, typically as a crystalline powder. It is stable under normal conditions and is not hygroscopic, meaning it does not readily absorb moisture from the air.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
346.50
Boiling point (Kelvin)
619.65
General information
Molecular weight
494.54g/mol
Molar mass
319.3680g/mol
Density
1.3000g/cm3
Appearence

Trimethobenzamide is typically a white or off-white crystalline powder. Its texture may vary from fine to slightly granular, but it generally maintains a consistent, solid appearance across different batches. This compound does not have a distinct odor.

Comment on solubility

Solubility of 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate

The solubility of the compound C24H34N2O8, known as 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate, can be influenced by several factors. Understanding its solubility is critical for its applications in pharmaceutical formulations and organic synthesis. Here are some key points regarding its solubility:

  • Polarity: Given the presence of multiple methoxy groups and an ester function, the compound may exhibit moderate polarity, affecting its interaction with various solvents.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or methanol, rather than in water due to its hydrophobic regions.
  • Temperature Influence: Generally, solubility increases with temperature; thus, heating may enhance the dissolution of this compound in less polar solvents.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, particularly if the compound can ionize under different pH conditions.

As a result, it is essential to consider these factors when predicting the solubility of this complex compound in different media. Understanding its solubility profile can greatly impact its practical applications in scientific research and industry.

Interesting facts

Interesting Facts about 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate

This compound, known for its complexity and specific applications, is a fascinating example of modern organic chemistry. It falls under the category of benzoate esters, enriched with multiple functional groups, adding to its intriguing properties. Here are some compelling points to consider:

  • Structural Elegance: The presence of a 1,4-diazepane structure indicates that the compound might possess interesting biological activities, particularly in medicinal chemistry.
  • Trimethoxybenzoyl Moiety: The inclusion of trimethoxy functionalities is noteworthy. These groups can enhance lipophilicity, facilitating better interaction with biological membranes.
  • Potential Therapeutic Applications: Compounds like this one are often explored for their role in drug development due to their ability to interact with various biological targets. Such structures could potentially influence neurotransmitter systems or act as anti-inflammatory agents.
  • Synthetic Complexity: The synthesis of such compounds often involves intricate multi-step processes, making them both challenging and rewarding for chemists. It's an excellent case for the application of advanced synthetic methods.
  • Examples in Nature: While this compound is synthetic, it draws inspiration from naturally occurring compounds that may have similar functional groups and biological activities, highlighting the endless creativity of nature's chemistry.

In summary, 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate showcases the intersection of complexity and function in chemical design. Each of its components can offer insights into both fundamental chemistry and practical applications in fields like pharmacology and biotechnology.

Synonyms
Dilazep
35898-87-4
Dilazep [INN]
Dilazepam
Dilazepum
Dilazepum [INN-Latin]
Dilazepam [INN-Spanish]
UNII-F8KLC2BD5Z
F8KLC2BD5Z
Dilazep (INN)
DTXSID9045425
DILAZEP [MI]
DILAZEP [WHO-DD]
KI 2119
3,3'-(1,4-Diazepan-1,4-diyl)dipropyl bis(3,4,5-trimethoxybenzoat)
CHEMBL126075
Benzoic acid, 3,4,5-trimethoxy-, (tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester
DTXCID7025425
CHEBI:92842
Tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanol 3,4,5-trimethoxybenzoate (diester)
NCGC00016747-03
Dilazepum (INN-Latin)
1,4-Bis(3,4,5-trimethoxybenzyloxy)propyl)perhydro-1,4-diazepin
Dilazepam (INN-Spanish)
3,3'-(1,4-Diazepan-1,4-diyl)dipropyl bis(3,4,5-trimethoxybenzoat) [IUPAC]
3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate
3-{4-[3-(3,4,5-trimethoxybenzoyloxy)propyl]-1,4-diazepan-1-yl}propyl 3,4,5-trimethoxybenzoate
(1,4-diazepane-1,4-diyl)di(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate)
Benzoic acid, 3,4,5-trimethoxy-,(tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester
CAS-35898-87-4
Biopropazepan Trimethoxybenzoate
N,N'-bis(3-(3,4,5-trimethoxybenzoyloxy)propyl)homopiperazine
N,N'-bis[3-(3,4,5-trimethoxybenzoyloxy)propyl]homopiperazine
Trimethoxybenzoate, Biopropazepan
3,3'-(1,4-Diazepan-1,4-diyl)dipropyl bis(3,4,5-trimethoxybenzoat) (IUPAC)
3-(4-(3-(3,4,5-trimethoxybenzoyloxy)propyl)-1,4-diazepan-1-yl)propyl 3,4,5-trimethoxybenzoate
Tocris-0481
Prestwick0_000236
Prestwick1_000236
Prestwick2_000236
Prestwick3_000236
Lopac0_000369
SCHEMBL48830
BSPBio_000311
SPBio_002232
BPBio1_000343
GTPL4717
C01DX10
GLXC-25687
HMS2090A11
Tox21_110588
BDBM50017691
Tox21_110588_1
DB13715
NCGC00016747-01
NCGC00016747-02
NCGC00016747-04
NCGC00016747-05
NCGC00016747-07
NCGC00024610-01
NCGC00024610-02
CAS-20153-98-4
NS00004756
D07843
Q5276700
SR-01000075817-3
BRD-K48722258-003-04-5
BRD-K48722258-300-03-7
BRD-K48722258-300-05-2
BRD-K48722258-300-07-8
BRD-K48722258-300-10-2
BRD-K48722258-300-11-0
1,4-diazepane-1,4-diyldipropane-3,1-diyl bis(3,4,5-trimethoxybenzoate)
(1,4-Diazepane-1,4-diyl)bis(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate)
3,3'-(1,4-diazepane-1,4-diyl)bis(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate)
tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanediyl-3,4,5-trimethoxybenzoate
3,4,5-trimethoxybenzoic acid 3-[4-[3-[oxo-(3,4,5-trimethoxyphenyl)methoxy]propyl]-1,4-diazepan-1-yl]propyl ester
8DZ