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Carbidopa

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Identification
Molecular formula
C10H14N2O4
CAS number
28860-95-9
IUPAC name
3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid
State
State

At room temperature, carbidopa is in a solid state, typically in the form of crystalline powder.

Melting point (Celsius)
203.50
Melting point (Kelvin)
476.65
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
244.24g/mol
Molar mass
244.2510g/mol
Density
1.4900g/cm3
Appearence

Carbidopa is typically a white to off-white crystalline powder. It is relatively stable and decomposes at higher temperatures.

Comment on solubility

Solubility of 3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid (C10H14N2O4)

The solubility of 3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid is influenced by several factors, including its chemical structure and functional groups. The presence of hydroxyl (-OH) groups is particularly significant as they are polar and can form hydrogen bonds with water, thereby enhancing the compound's solubility.

Key Points about Solubility:

  • Polarity: The molecule’s polarity due to the hydroxyl groups indicates that it is likely to be soluble in polar solvents, especially water.
  • Hydrogen Bonding: The ability to form hydrogen bonds may lead to higher solubility in aqueous solutions.
  • Symmetry and Structure: The overall symmetry and sterics of the molecule play a crucial role in its solubility behavior.
  • Temperature Influence: Solubility can increase with temperature, a common characteristic for many chemical compounds.

In conclusion, while specific solubility information may vary based on experimental conditions, it can be inferred that the structural features of 3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid would generally favor solubility in polar environments. As always, empirical testing under defined conditions remains essential to ascertain precise solubility characteristics.

Interesting facts

Interesting Facts About 3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic Acid

3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid, often referred to as a bioactive molecule, boasts intriguing characteristics that make it a subject of scientific interest.

Biological Relevance

  • Antioxidant Properties: This compound is known for its potential antioxidant effects, which may help in neutralizing free radicals in biological systems.
  • Hygroscopic Behavior: Its hydrazine moiety can exhibit interesting reactions with various biological targets, making it relevant in medicinal chemistry.
  • Research Applications: It is being investigated for its roles in reducing oxidative stress and implications in neurodegenerative diseases.

Synthesis and Derivatives

The synthesis of this compound often involves innovative techniques in organic chemistry. Its derivatives can be explored for:

  • Enhanced Solubility: Modifying the structure may improve solubility and bioavailability.
  • Targeted Therapies: Exploring analogs can lead to targeted therapies for various ailments due to its hydrazino functional group.

Quote to Reflect On

As noted by many researchers in the field, "The uniqueness of a compound lies not just in its molecular structure, but in the multiple biological pathways it can influence." This sentiment rings particularly true for compounds like 3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid, which exhibit diverse biological activities.

In conclusion, the exploration of such compounds not only enriches our understanding of chemistry but also paves the way for potential breakthroughs in pharmacology and therapeutic applications.

Synonyms
302-53-4
dl-Carbidopa
D,L-Carbidopa
3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
Carbidopa, dl-
D,L CARBIDOPA
Carbidopa, dl- anhydrous
Carbidopa anhydrous, DL-
Carbidopa DL-form [MI]
14585-65-0
555UP07D5N
NSC-92521
Carbidopa (monohydrate)
alpha-Methylhydrazinodopa
DL-Carbidopa [WHO-DD]
dl-MK 485
Lodosin
UNII-555UP07D5N
Carbidopa 1-hydrate
Spectrum_001314
Spectrum2_001115
Spectrum3_001517
Spectrum4_000603
Spectrum5_001039
.alpha.-Methyldopahydrazine
Hydrazino-.alpha.-methyldopa
BSPBio_003193
KBioGR_001126
KBioSS_001794
MLS006011894
DivK1c_000168
L-.alpha.-Methyldopahydrazine
SPECTRUM1502150
SPBio_001250
SCHEMBL2688295
alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
CHEMBL1179357
CHEBI:94430
HMS500I10
KBio1_000168
KBio2_001794
KBio2_004362
KBio2_006930
KBio3_002693
DTXSID80860427
Benzenepropanoic acid, .alpha.-hydrazino-3,4-dihydroxy-.alpha.-methyl-, (S)-
NINDS_000168
TZFNLOMSOLWIDK-UHFFFAOYSA-N
HMS2092D16
Pharmakon1600-01502150
adjunct to levodopa in parkinsonism
dl-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
NSC92521
BBL011329
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-
CCG-40066
MFCD02114422
MK 846
NSC 92521
NSC758190
STL146415
AKOS005721170
FC19695
GS-3140
IDI1_000168
NCGC00015185-02
NCGC00015185-03
NCGC00015185-04
NCGC00095918-01
NCGC00095918-02
SMR003309278
SBI-0051733.P002
(-)-l-.alpha.-Hydrazino-3,4-dihydroxy-.alpha.-methylhydrocinnamic acid monohydrate
DB-047475
DB-229777
DS-010214
NS00125562
S-(-)-Carbidopa, >=98% (TLC), powder
SR-05000001752
SR-05000001752-1
BRD-A69512159-001-01-6
BRD-A69512159-001-03-2
BRD-A69512159-001-06-5
Q27166292
Benzenepropanoic acid,4-dihydroxy-.alpha.-methyl-, (.+-.)-
3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid-, (S)-
BENZENEPROPANOIC ACID, A-HYDRAZINYL-3,4-DIHYDROXY-A-METHYL-
(-)-L-.alpha.-Hydrazino-3,4-dihydroxy-.alpha.-methylhydrocinnamic acid
DL-.ALPHA.-HYDRAZINO-3,4-DIHYDROXY-.ALPHA.-METHYLHYDROCINNAMIC ACID
Hydrocinnamic acid, .alpha.-hydrazino-3,4-dihydroxy-.alpha.-methyl-, L-
l-alpha-hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
(2RS)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic Acid (rac-Carbidopa)
3-(3,4-Dihydroxyphenyl)-2-hydraZinyl-2-methylpropanoic acid (DL-N(NH2)aMeTyr(3-OH)-OH)
BENZENEPROPANOIC ACID, .ALPHA.-HYDRAZINO-3,4-DIHYDROXY-.ALPHA.-METHYL-
L-.alpha.-Methyl-.alpha.-hydrazino-.beta.-(3,4-dihydroxyphenylpropionic acid
L-.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)-.alpha.-hydrazinopropionic acid
a-Hydrazino-3,4-dihydroxy-a-methyl-benzenepropanoic acid;DL-a-Hydrazino-3,4-dihydroxy-a-methylhydrocinnamic acid;a-Hydrazino-a-methy ldopa;(+)-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic acid monohydrate;dl-MK 485