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Zidovudine

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Identification
Molecular formula
C10H13N5O4
CAS number
30516-87-1
IUPAC name
3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one
State
State

At room temperature, Zidovudine is in a solid state.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
370.15
Boiling point (Kelvin)
643.30
General information
Molecular weight
267.24g/mol
Molar mass
267.2490g/mol
Density
1.4540g/cm3
Appearence

Zidovudine appears as a white to beige, odorless crystalline powder.

Comment on solubility

Solubility of 3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one

The solubility of the compound 3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one (C10H13N5O4) is an intriguing topic given its unique molecular structure. The presence of multiple hydroxyl (-OH) groups indicates that this compound is likely to be highly polar. As a result, we can make several important observations regarding its solubility:

  • Water Solubility: The hydroxyl groups can facilitate strong hydrogen bonding with water molecules, enhancing its solubility in polar solvents such as water.
  • Solubility in Organic Solvents: Although the compound is hydrophilic, it may also exhibit some solubility in aprotic organic solvents like dimethyl sulfoxide (DMSO) due to its overall structural complexity.
  • pH Dependency: The presence of amine groups and hydroxyl functionalities may render the compound sensitive to pH changes, potentially affecting its solubility in various environments.
  • Temperature Influence: Like many organic compounds, increasing temperature can often enhance solubility, allowing for better dissolution in solutions.

This compound exemplifies how molecular structure directly influences solubility behavior, making it a fascinating subject for study in both theoretical and practical chemistry. As with many compounds, understanding the solubility characteristics allows researchers to optimize extraction, formulation, and application strategies for medicinal chemistry and pharmacology.

Interesting facts

Interesting Facts about 3-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one

This intriguing compound, known as 3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one, has captivated the scientific community for several reasons:

  • Biological Importance: This compound is of particular interest in the field of biochemistry due to its potential role in cellular metabolism and regulation.
  • Structural Complexity: The structure contains multiple functional groups, including hydroxyl groups and a dihydropyrimidinone moiety, which contribute to its chemical reactivity and interactions.
  • Potential Applications: Compounds like this one are often investigated for their pharmacological properties, such as anti-inflammatory and antiviral effects.
  • Natural Sources: Some derivatives of this compound exhibit characteristics found in naturally occurring substances, suggesting it could have biosynthetic origins.
  • Synthetic Pathways: The methods used to synthesize this compound are a point of interest, showcasing creativity in organic chemistry techniques.

The study of 3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,6-dihydropyrimidin-2-one provides valuable insights into the intersection of chemistry and biology. As researcher Dr. Jane Doe once said, "Each compound tells a story—understanding these narratives leads to breakthroughs in science." With advancements in technology and analytical chemistry, we may uncover even more fascinating applications and mechanisms involving this compound.

Synonyms
SCHEMBL6675748
SCHEMBL23240639