Skip to main content

Guaiacol glyceryl ether

ADVERTISEMENT
Identification
Molecular formula
C10H14O4
CAS number
93-14-1
IUPAC name
3-(2-methylphenoxy)propane-1,2-diol
State
State

At room temperature, Guaiacol glyceryl ether is in a solid state. It is stable under normal conditions but should be stored in a cool, dry place away from light to prevent degradation.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
198.22g/mol
Molar mass
198.2170g/mol
Density
1.0820g/cm3
Appearence

Guaiacol glyceryl ether, commonly known as Guaifenesin, typically appears as a white crystalline powder. It is often described as having a bitter taste. The crystals are fine and may clump together when compressed but can easily be powdered.

Comment on solubility

Solubility of 3-(2-methylphenoxy)propane-1,2-diol (C10H14O4)

3-(2-methylphenoxy)propane-1,2-diol is a compound that exhibits an interesting solubility profile due to its molecular structure. The solubility characteristics can be summarized as follows:

  • Polarity: The presence of hydroxyl groups (-OH) contributes to its polar nature, which typically enhances solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in water and other polar solvents such as ethanol and methanol.
  • Hydrophobic Interactions: The aromatic ring from the 2-methylphenoxy moiety introduces some hydrophobic characteristics, which may limit solubility in non-polar solvents.
  • Temperature Dependence: Solubility may increase with temperature, making it more soluble at elevated temperatures, which is common for many organic compounds.

In summary, while 3-(2-methylphenoxy)propane-1,2-diol shows good solubility in polar solvents due to its hydroxyl groups, the hydrophobic nature of its aromatic component can limit its solubility in non-polar environments. This dual behavior is pivotal for applications involving solvent selection and formulation development.

Interesting facts

Interesting Facts about 3-(2-methylphenoxy)propane-1,2-diol

3-(2-methylphenoxy)propane-1,2-diol, a compound known for its unique structure and properties, has attracted the attention of many researchers in the fields of organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structure and Functionality: This compound features a phenoxy group that is linked to a propane diol structure, contributing to its polarity and reactivity. Its structure allows for multiple interactions with biological systems, potentially influencing its activity in various applications.
  • Biological Relevance: Compounds like 3-(2-methylphenoxy)propane-1,2-diol are often investigated for their role in drug design. They can act as intermediates in the synthesis of more complex pharmaceuticals, highlighting their relevance in medicinal chemistry.
  • Applications in Industry: Beyond pharmaceuticals, this compound may find utility in the production of specialty chemicals and polymers. Its functionality can be harnessed in formulations that require surfactant properties, contributing to its commercial significance.
  • Synthetic Pathways: The synthesis of this compound can involve multiple steps and methods, often requiring the use of catalysts or specific reaction conditions to generate desired yields. Understanding these pathways is crucial for optimizing production and enhancing efficiency in laboratories.
  • Research Frontier: As a compound with diverse applications, ongoing studies continue to unravel its potential, revealing how slight modifications in its structure could lead to significant changes in activity and effectiveness in various contexts.

In conclusion, 3-(2-methylphenoxy)propane-1,2-diol is more than just a simple organic compound; its varied functionalities and potential applications make it a fascinating subject of study. As research advances, we may discover even more intriguing facets of this compound that could lead to innovative solutions in chemistry and related fields.

Synonyms
mephenesin
59-47-2
Mephenesine
Cresoxydiol
Lissephen
Mefenesina
Memphenesin
Mephedan
Tolserol
Decontractil
Decontractyl
Myodetensine
Anatensin
Cresodiol
Dioloxol
Lissenphan
Mephelor
Mephesin
Myodetensin
Atensin
Curaril
Sinan
Kresoxypropandiol
3-(2-Methylphenoxy)propane-1,2-diol
Cresoxypropanediol
Cresossidiolo
Curarythan
Curythan
Dioloxal
Findolar
Findolor
Glukresin
Glykresin
Kinavosyl
Mepherol
Mephosal
Mervaldin
Mianesina
Miolisina
Moctynol
Myanesin
Myastenin
Myocuran
Myolysin
Myoserol
Nembusen
Nephelor
Noctynol
Oranixon
Prolaxin
Proloxin
Relaxant
Renarcol
Sansdolor
Seconesinz
Spartoloxin
Spartoloxyn
Spasmolyn
Stilalgin
Thioxidil
Thoxidil
Tolansin
Tolofren
Tolosate
Tolulexin
Tolydrin
Anxine
Avesyl
Avosyl
Avoxil
Avoxyl
Daserd
Daserol
Diloxol
Glyotol
Glytol
Halabar
Mephate
Mephin
Mephson
Myanil
Myanol
Myasin
Myolax
Myopan
Myopen
Myopna
Myosera
Myoten
Myoxane
Myoxyl
Prolax
Relaxar
Relaxil
Saserol
Temian
Tokerol
Tolbart
Tolcil
Tolhart
Toloxyn
Tolsil
Tolsin
Tolulox
Tolynol
Torulox
Tolax
Xeral
Rhex regulans
Walko-Nesin
Cresossipropandiolo
1,2-Propanediol, 3-(2-methylphenoxy)-
Relaxyl
Tolyspaz
Ortol
o-Cresyl glycerol ether
3-(o-Tolyloxy)propane-1,2-diol
Ageflex CGE
3-(2-Methylphenoxy)-1,2-propanediol
Rhex 'hobeino'
Glyceryl o-tolyl ether
o-Cresol glyceryl ether
Mephenesinum
1-o-Tolylglycerol ether
o-Kresol-glycerinaether
BYK-M 1
3-o-Toloxy-1,2-propanediol
Mephensin
3-(o-Methylphenoxy)-1,2-propanediol
1-Ortho-tolylglycerol ether
BDH 312
3-(2-Tolyloxy)-1,2-propanediol
Mefenesina [INN-Spanish]
Mephenesine [INN-French]
Mephenesinum [INN-Latin]
RP 3602
SQ 1156
3-(o-Tolyloxy)-1,2-propanediol
1,2-Dihydroxy-3-(2-methylphenoxy)propane
o-Cresyl alpha-glyceryl ether
alpha-(o-Tolyl)glyceryl ether
Walconesin
Mycocuran
Tolseron
A 1141
o-Kresol-glycerinaether [German]
EINECS 200-427-4
Mephenesin [INN:BAN:NF]
NSC 25234
NSC-25234
Mephenesin (INN)
Tolserol (TN)
BRN 2047373
DTXSID4023254
1,2-PROPANEDIOL, 3-(o-TOLYLOXY)-
7B8PIR2954
MEPHENESIN [MI]
MEPHENESIN [INN]
MEPHENESIN [MART.]
alpha,beta-Dihydroxy-gamma-(2-methylphenoxy)propane
MEPHENESIN [WHO-DD]
Mefensina
Rex regulans
DTXCID803254
Walco-Nesin
o-Cresyl .alpha.-glyceryl ether
.alpha.-(o-Tolyl)glyceryl ether
NSC25234
component of Tolagesic
NCGC00094908-01
1, 3-(o-tolyloxy)-
Mefenesina (INN-Spanish)
Mephenesine (INN-French)
Mephenesinum (INN-Latin)
MEPHENESIN (MART.)
WLN: Q1YQ1OR B1
1, 3-(2-methylphenoxy)-
.alpha.,.beta.-Dihydroxy-.gamma.-(2-methylphenoxy)propane
SR-05000001772
DAcontractyl
Rhex
UNII-7B8PIR2954
Rhex'hobeino'
CAS-59-47-2
Prestwick_577
Mephenesin, 98%
(S)-3-(2-Methylphenoxy)propane-1,2-diol
1-(o-tolyl)glycerol
Mephenesin (Standard)
1-(2-tolyl)glycerol
Spectrum_001402
Prestwick0_000178
Prestwick1_000178
Prestwick2_000178
Prestwick3_000178
Spectrum2_001418
Spectrum3_000908
Spectrum4_001007
Spectrum5_001199
(.+/-.)-Mephenesin
1-(2-methylphenyl)glycerol
SCHEMBL25448
BSPBio_000075
KBioGR_001473
KBioSS_001882
DivK1c_000076
SPECTRUM1501140
SPBio_001496
SPBio_001996
BPBio1_000083
CHEMBL229128
CHEBI:94398
HMS500D18
HY-B1283R
KBio1_000076
KBio2_001882
KBio2_004450
KBio2_007018
KBio3_001856
M03BX06
NSC8134
NINDS_000076
HMS1568D17
HMS1921J09
HMS2092F17
HMS2095D17
HMS3712D17
HMS3886K09
Pharmakon1600-01501140
HY-B1283
NSC-8134
NSC36140
NSC50788
GLYCEROL-1-(O-TOLYL) ETHER
Tox21_111356
CCG-38970
MFCD00004718
NSC-36140
NSC-50788
NSC757857
s5032
STL430456
AKOS015912866
Tox21_111356_1
CS-5340
DB13583
NSC-757857
IDI1_000076
1,2-Propanediol, 3-(2-methylphenoxy)
NCGC00094908-02
NCGC00094908-03
NCGC00094908-06
DA-55344
3-[(2-methylphenyl)oxy]propane-1,2-diol
SBI-0051654.P002
AB00052216
M3076
NS00001081
3-(2-Methylphenoxy)-1 pound not2-propanediol
D02595
D97581
AB00052216_04
EN300-7408655
A923330
Q3333250
SR-05000001772-1
SR-05000001772-2
SR-05000001772-3
BRD-A55469827-001-01-7
BRD-A55469827-001-07-4
200-427-4