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Clavulanic acid

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Identification
Molecular formula
C8H9NO5
CAS number
58001-44-8
IUPAC name
3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, clavulanic acid is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
308.20
Boiling point (Kelvin)
581.35
General information
Molecular weight
199.17g/mol
Molar mass
199.1550g/mol
Density
1.6400g/cm3
Appearence

Clavulanic acid typically appears as a white to off-white crystalline powder. It is sensitive to air and light, and its color may darken upon exposure. This compound is primarily used in its sodium or potassium salt form for medical applications.

Comment on solubility

Solubility of 3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C8H9NO5)

The solubility of 3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is influenced by its functional groups and molecular structure. As a compound containing both carboxylic acid and hydroxyl groups, it is expected to exhibit a favorable solubility profile in polar solvents. Here are some important points to consider:

  • Polar Solvents: The presence of a carboxylic acid group typically increases solubility in water and other polar solvents, due to the ability to form hydrogen bonds.
  • Hydrophobic Regions: The bicyclic structure may introduce some hydrophobic character, potentially limiting solubility in less polar solvents.
  • pH Dependency: The solubility can vary with pH, particularly as the carboxylic acid can donate protons, affecting ionic forms in solution.

In summary, while the compound is likely to be soluble in water and other polar solvents due to its functional groups, factors like molecular structure and environmental conditions must be considered to fully understand its solubility characteristics. As a general observation, "like dissolves like" holds true; thus, the ability of 3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid to dissolve in various solvents may significantly depend on the polarity of the solvent used.

Interesting facts

Interesting Facts about 3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This intriguing compound, with a complex structure, showcases some fascinating aspects that make it a subject of interest in the field of chemistry and biochemistry.

Unique Structural Features

The compound is notable for its bicyclic structure, which presents a rare blend of:

  • Azabicyclo Structure: It contains a nitrogen atom within its bicyclic formation, enhancing its chemical variability.
  • Carboxylic Acid Group: This group contributes to the compound's acidity and plays a crucial role in its reactivity.
  • Hydroxyethylidene Functionality: The presence of this moiety hints at its potential interactions with biological systems.

Biological Importance

Research suggests that compounds similar to this one are integral in various biological activities:

  • They may act as precursors to important biomolecules.
  • They exhibit potential therapeutic properties against certain diseases due to their structural complexity.

Applications in Chemistry

In the field of synthetic chemistry, this compound might serve as:

  • A building block in the synthesis of more complex molecules.
  • A ligand in coordination chemistry, potentially binding with metal ions to form interesting complexes.

Quote for Inspiration

As the famous chemist Linus Pauling once said: "The best way to have a good idea is to have lots of ideas." This compound exemplifies the creativity and complexity found within the realm of organic chemistry.

Overall, 3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is more than just a chemical formula; it is a testament to the intricate possibilities that await exploration in chemical and biological sciences.

Synonyms
3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylate
3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
DTXSID20860724
BCP09032
MB01537
BRL14151; BRL-14151; BRL 14151; MM14151; MM-14151; MM 14151