Interesting facts
Interesting Facts about 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one
This unique compound, 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one, belongs to the family of indoline derivatives, which are well-regarded in medicinal chemistry for their broad spectrum of biological activities. Here are some intriguing aspects of this compound:
- Biological Significance: Indole and indoline derivatives are often studied for their potential in pharmaceuticals. They exhibit various pharmacological activities, including antitumor, antidepressant, and anti-inflammatory effects.
- Structure and Function: The compound features a complex structure that incorporates both chloro and methylene groups, positioning it favorably for interactions with biological pathways. The presence of chlorine is known to enhance certain properties, such as lipophilicity and binding affinity.
- Research Potential: With the advancements in drug discovery, compounds like this one are often evaluated for their activity against various cancer cell lines. This opens up avenues for new treatments and therapeutic agents.
- Synthetic Routes: The synthesis of indoline derivatives can involve unique strategies, often employing multi-step reactions that illustrate the complexity and creativity in modern organic synthesis.
- Vibrant Interactions: The ability of this compound to participate in hydrogen bonding and π-π stacking interactions is crucial for its biological activity, making it a subject of interest for studies in molecular recognition.
In conclusion, the exploration of 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one represents a fascinating intersection of chemistry and pharmacology, where researchers are continually unveiling its potential benefits in treating various health conditions. As we advance our knowledge in this field, such compounds could pave the way for groundbreaking discoveries.
Synonyms
220749-41-7
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
cdk1 inhibitor
3-[(2-chloro-1H-indol-3-yl)methylidene]-2,3-dihydro-1H-indol-2-one
cmpd 8a
CDK1 inhibitor 8a
2H-Indol-2-one, 3-[(2-chloro-1H-indol-3-yl)methylene]-1,3-dihydro-
GLXC-25064
HMS3674K15
AKOS028110668
NCI60_041122
F82221
Q27194430
Solubility of 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one (C17H11ClN2O)
The solubility of 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one is influenced by its molecular structure and functional groups. This compound exhibits the following characteristics in terms of solubility:
In summary, while the solubility profile of 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one is likely limited in water, it may dissolve readily in various organic solvents, making it suitable for applications in organic synthesis and medicinal chemistry.