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Serotonin

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Identification
Molecular formula
C10H12N2O
CAS number
50-67-9
IUPAC name
3-(2-aminopropyl)-1H-indol-5-ol
State
State

At room temperature, serotonin exists as a solid. Its exact form depends on the specific polymorph, but it is generally powdery and crystalline in nature.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.20
Boiling point (Celsius)
512.10
Boiling point (Kelvin)
785.30
General information
Molecular weight
176.22g/mol
Molar mass
176.2160g/mol
Density
1.4650g/cm3
Appearence

Serotonin, commonly known by its chemical name 3-(2-aminopropyl)-1H-indol-5-ol, is typically a solid at room temperature. It forms as white to slightly off-white crystalline powder. In pure form, it can also appear as transparent or colorless crystals.

Comment on solubility

Solubility of 3-(2-aminopropyl)-1H-indol-5-ol (C10H12N2O)

The solubility of 3-(2-aminopropyl)-1H-indol-5-ol is influenced by its chemical structure, which contains both hydrophilic and hydrophobic regions. This dual character can lead to variable solubility depending on the solvent used:

  • Aqueous Solubility: Given the presence of the hydroxyl (-OH) and amine (-NH2) functional groups, this compound is expected to have moderate to good solubility in water. These polar groups can interact with water molecules through hydrogen bonding.
  • Organic Solvents: The solubility in organic solvents may vary. Due to the indole ring system, the compound might show better solubility in non-polar solvents like chloroform or dichloromethane.
  • Temperature Effects: Solubility often increases with temperature; thus, heating the solvent may enhance the dissolution of this compound in both polar and non-polar environments.

It is key to highlight that solubility can also be affected by factors such as:

  • pH of the solution: The ionization of the amine group may change under different pH conditions, significantly impacting solubility.
  • Presence of other solutes: The interaction with other compounds can lead to salting-out or salting-in effects, altering solubility profiles.

In summary, while 3-(2-aminopropyl)-1H-indol-5-ol is likely to be soluble in various solvents, the specific conditions will play a crucial role in determining its solubility behavior.

Interesting facts

Interesting Facts about 3-(2-Aminopropyl)-1H-indol-5-ol

3-(2-aminopropyl)-1H-indol-5-ol is a fascinating compound that plays significant roles in various fields of research. Here are some key insights:

  • Biological Importance: This compound is a derivative of indole, a structure that is found in many biologically active compounds, including neurotransmitters such as serotonin. Its chemical structure contributes to a range of physiological activities.
  • Potential Therapeutic Uses: Research indicates that similar indole derivatives may exhibit antipsychotic and antidepressant properties, making this compound an interesting subject for pharmacological studies. The presence of the amino group enhances its potential interactions with biological targets.
  • Research Tool: Due to its structural characteristics, 3-(2-aminopropyl)-1H-indol-5-ol can serve as a useful tool in medicinal chemistry for the development of new drugs aimed at treating psychiatric conditions.
  • Chemical Synthesis: The synthesis of this compound can involve multi-step processes, showcasing the intriguing chemistry involved in creating complex organic molecules. Understanding its synthetic pathways can enhance knowledge in organic synthesis techniques.
  • Analytical Interest: The compound's structural features make it a prime candidate for various analytical techniques, allowing chemists to explore its properties, reactivity, and potential applications in material science.

As we continue to unveil the mysteries of organic compounds like 3-(2-aminopropyl)-1H-indol-5-ol, it’s important to acknowledge how their unique structures foster a better understanding of their roles in both nature and the lab. This compound stands at the intersection of chemistry and biology, exemplifying the diverse ways in which molecules influence our world.

Synonyms
3-(2-aminopropyl)-1H-indol-5-ol
alpha-methyl-5-HT
304-52-9
alpha-Methylserotonin
1H-Indol-5-ol, 3-(2-aminopropyl)-
alpha-Methyl-5-hydroxytryptamine
5Y83TBC5NM
Indol-5-ol, 3-(2-aminopropyl)-
CHEMBL275854
5-hydroxy-alpha-methyltryptamine
CHEBI:48295
DTXSID10657549
(+/-)-alpha-Methyl-5-hydroxytryptamine
.ALPHA.-METHYL-5-HYDROXYTRYPTAMINE
5-HYDROXY-.ALPHA.-METHYLTRYPTAMINE
(+/-)-.ALPHA.-METHYL-5-HYDROXYTRYPTAMINE
4a-methyl-5-hydroxytryptamine
3-(2-Amino-propyl)-1H-indol-5-ol
alpha-M-5-HT
Biomol-NT_000085
UNII-5Y83TBC5NM
Lopac0_000823
GTPL152
SCHEMBL396996
.ALPHA.-METHYLSEROTONIN
BPBio1_001083
Alpha Methyl 5 Hydroxytryptamine
DTXCID50837949
LYPCGXKCQDYTFV-UHFFFAOYSA-N
BDBM50014945
PDSP1_001117
PDSP1_001679
PDSP2_001101
PDSP2_001662
CCG-204907
MB03476
SDCCGSBI-0050800.P002
NCGC00015629-03
NCGC00015629-04
NCGC00015629-05
NCGC00015629-08
NCGC00024651-02
NCGC00024651-03
101541-58-6
EN300-7473343
L001159
Q4734914
BRD-A17745711-050-05-4
BRD-A17745711-103-01-0
Z1255489555
848-087-1