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3-(1H-pyrrol-2-ylmethylene)indolin-2-one

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Identification
Molecular formula
C15H10N2O
CAS number
14265-44-2
IUPAC name
3-(1H-pyrrol-2-ylmethylene)indolin-2-one
State
State

At room temperature, 3-(1H-pyrrol-2-ylmethylene)indolin-2-one is in a solid state. It typically presents in powder or crystalline form, stable under normal laboratory conditions.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
429.50
Boiling point (Kelvin)
702.65
General information
Molecular weight
222.25g/mol
Molar mass
222.2450g/mol
Density
1.3470g/cm3
Appearence

3-(1H-pyrrol-2-ylmethylene)indolin-2-one appears as a crystalline solid. The color may range from pale yellow to an orange hue depending on purity and specific conditions such as light exposure. It is often used in scientific studies and can appear somewhat translucent.

Comment on solubility

Solubility of 3-(1H-pyrrol-2-ylmethylene)indolin-2-one (C15H10N2O)

The solubility characteristics of 3-(1H-pyrrol-2-ylmethylene)indolin-2-one are of particular interest due to its unique chemical structure and potential applications in various fields such as pharmaceuticals and materials science.

In general, the solubility of a compound is influenced by several factors, including:

  • Molecular Structure: The presence of polar functional groups can enhance solubility in polar solvents.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds typically exhibit increased solubility in solvents that can also engage in hydrogen bonding.
  • Temperature: Solubility often increases with temperature, making thermal conditions an important consideration in solubility assessments.

For 3-(1H-pyrrol-2-ylmethylene)indolin-2-one, its aromatic rings are juxtaposed with the nitrogen-containing pyrrole and imine functionalities, which indicates potential solubility properties in organic solvents such as:

  • DMSO (Dimethyl sulfoxide)
  • DMF (Dimethylformamide)
  • Alcohols

However, it's crucial to note that the solubility can still be limited in aqueous environments due to the hydrophobic nature of the indole rings and the overall non-polar characteristics of the compound in water. For practical applications, a thorough investigation into specific solvent interactions and concentration effects would generate a more detailed understanding of its solubility regime.

In summary, while the solubility of 3-(1H-pyrrol-2-ylmethylene)indolin-2-one may favor organic solvents, comprehensive solubility data is necessary to optimize its use in various chemistries.

Interesting facts

Interesting Facts about 3-(1H-pyrrol-2-ylmethylene)indolin-2-one

3-(1H-pyrrol-2-ylmethylene)indolin-2-one is a fascinating compound that merges the intriguing properties of both indoline and pyrrole structures, making it a subject of interest in various fields of chemistry and pharmacology. Here are some remarkable aspects of this compound:

  • Structural Duality: The combination of indoline and pyrrole gives this molecule a unique structural framework that allows for diverse reactivity and interaction with biological systems.
  • Potential Biological Activity: Compounds featuring the indolin-2-one skeleton have been explored for their potential therapeutic effects, particularly as antidepressants and antitumor agents.
  • Framework Versatility: The presence of a pyrrole ring can enable various substitution reactions, paving the way for the synthesis of numerous derivatives with modified properties.
  • Aromatic Stability: This compound boasts a conjugated system that not only contributes to its stability but also enhances its potential as a light-absorbing agent in organic solar cell applications.
  • Research Interest: Its complex structure makes it an attractive target for research, especially in the fields of organic synthesis and medicinal chemistry.

The exploration of 3-(1H-pyrrol-2-ylmethylene)indolin-2-one is not just limited to its synthesis but also extends to its applications in drug discovery and materials science. As researchers delve deeper into its properties, we can expect to uncover even more about this compound's intriguing potential.

As one scientist aptly noted, "Nature has a clever way of intertwining the simple with the complex." In this compound, we see just that—a perfect blend of simplicity in its base structure and complexity in its chemical behaviors and potential applications.

Synonyms
Kinome_2851
3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one
91822-51-4
Kinome_2852
3-(1H-Pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one
CHEMBL1996176
SEZFNTZQMWJIAI-UHFFFAOYSA-N
AKOS034344139
PD085041
3-((pyrrol-2-yl)methylene)-2-indolinone
DB-132356
Q27164652
1,3-Dihydro-3-(1H-pyrrol-2-ylmethylene)-2H-indol-2-one