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SU5416

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Identification
Molecular formula
C22H16N2O2
CAS number
204005-46-9
IUPAC name
3-(1H-indol-3-yl)-4-[1-[2-(2-piperidyl)ethyl]indol-3-yl]pyrrole-2,5-dione
State
State

This compound is typically in a solid state at room temperature, structured as a crystalline powder.

Melting point (Celsius)
114.50
Melting point (Kelvin)
387.65
Boiling point (Celsius)
645.15
Boiling point (Kelvin)
918.30
General information
Molecular weight
354.41g/mol
Molar mass
354.4080g/mol
Density
1.3800g/cm3
Appearence

SU5416 appears as a yellow, crystalline powder. It is often used in biochemical laboratories for research purposes.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)-4-[1-[2-(2-piperidyl)ethyl]indol-3-yl]pyrrole-2,5-dione

The solubility of 3-(1H-indol-3-yl)-4-[1-[2-(2-piperidyl)ethyl]indol-3-yl]pyrrole-2,5-dione (C22H16N2O2) greatly influences its applications in pharmaceutical formulations and chemical research. Understanding its solubility behavior is crucial; here are some key aspects to consider:

  • Solvent Compatibility: This compound is likely to exhibit varying solubility in different solvents, with expected higher solubility in organic solvents like dimethyl sulfoxide (DMSO) and possibly ethanol, while being less soluble in polar solvents like water.
  • Structural Considerations: The presence of multiple aromatic rings and the piperidine side chain can lead to significant interaction with solvents, impacting solubility. The indole substitutions may enhance solubility in non-polar solvents due to their hydrophobic nature.
  • Temperature Effects: Solubility can be influenced by temperature. Generally, increasing temperatures may increase solubility in solids. Assessing solubility at different temperatures can yield essential information for practical applications.
  • Solubility Product: Analyzing the solubility product can provide insights into how modifications to the molecular structure may affect overall solubility.

In summary, understanding the solubility of this compound is multi-faceted and involves evaluating solvent interactions, temperature effects, and the chemical structure's impact on solubility behaviors. A comprehensive solubility profile can facilitate innovative uses in pharmaceutical design and enhance its efficacy in various applications.

Interesting facts

Interesting Facts about 3-(1H-indol-3-yl)-4-[1-[2-(2-piperidyl)ethyl]indol-3-yl]pyrrole-2,5-dione

This compound, often referred to for its complex structure, incorporates fascinating features that reflect its potential in medicinal chemistry. One of the most intriguing aspects is that it contains both indole and pyrrole rings, which are prevalent in various natural products and bioactive molecules.

Biological Significance

The indole moiety is known for its presence in many serotonergic compounds, indicating the potential role of this compound in influencing neurotransmitter systems. Some interesting points include:

  • Indole Structure: Indole derivatives are extensively researched for their psychotropic effects and roles in mood regulation.
  • Piperidine Link: The inclusion of a piperidine group suggests possible interactions with neural receptors, making it a candidate for studying neurological pathways.
  • Potential Drug Development: Due to its structural features, it may serve as a starting scaffold for synthesizing therapeutic agents targeting various diseases.

Research Applications

Furthermore, this compound can be valuable in several research domains:

  • Pharmacology: Its ability to modulate biological systems opens pathways for drug discovery, particularly in neuropharmacology.
  • Organic Synthesis: The intricate structure highlights synthetic chemistry's complexities and opens avenues for developing new synthetic methodologies.
  • Cross-Disciplinary Studies: This compound can be studied at the intersection of chemistry, biology, and pharmacology, promoting a holistic understanding of drug interactions.

As chemists, we often marvel at how the arrangement of atoms can lead to significant differences in function and application. The intricate design of 3-(1H-indol-3-yl)-4-[1-[2-(2-piperidyl)ethyl]indol-3-yl]pyrrole-2,5-dione is a testament to this principle, sparking curiosity and innovation in chemical research.

Synonyms
CHEMBL403771
bisindolylmaleimide vi
Bisindolyl deriv. 23
BDBM2685
SCHEMBL16939692
BDBM50375055
3-(1H-indol-3-yl)-4-[1-(2-piperidin-2-ylethyl)indol-3-yl]pyrrole-2,5-dione
3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1H-indol-3-yl}-2,5-dihydro-1H-pyrrole-2,5-dione