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Tryptophan

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Identification
Molecular formula
C11H12N2O2
CAS number
73-22-3
IUPAC name
3-(1H-indol-3-yl)-2-(methylamino)propanoic acid
State
State

Tryptophan is a solid at room temperature. It is typically handled in a powdered form, often used in chemical and biochemical research, and is a significant compound in the field of biochemistry.

Melting point (Celsius)
289.00
Melting point (Kelvin)
562.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
204.23g/mol
Molar mass
204.2290g/mol
Density
1.3400g/cm3
Appearence

Tryptophan generally appears as an off-white crystalline powder. It is known to exist typically in a solid form at room temperature and its crystals have a distinctive shape that can be recognized under magnification.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)-2-(methylamino)propanoic acid (C11H12N2O2)

The solubility of 3-(1H-indol-3-yl)-2-(methylamino)propanoic acid, a compound notable for its structural features, can vary significantly based on several conditions. Understanding this solubility is crucial for its application in biochemical contexts.

Key Factors Affecting Solubility

  • Polarity: The presence of both a carboxylic acid group and an indole structure affects the compound's overall polarity. This typically increases solubility in polar solvents like water.
  • pH Level: The solubility of the compound may increase in acidic conditions, where the carboxylic acid group can remain protonated.
  • Temperature: Generally, an increase in temperature can enhance the solubility of solids. Thus, heating could potentially aid in dissolving this compound effectively.
  • Presence of Other Solutes: The solubility can also be influenced by co-solvents or ions in solution, which may interact with the compound.

In summary, while 3-(1H-indol-3-yl)-2-(methylamino)propanoic acid demonstrates *moderate solubility* in water, the factors listed above should be considered when evaluating its practical usage. As a general rule, it is always advisable to conduct experimental solubility tests under the intended conditions of use to achieve the most reliable results.

Interesting facts

Interesting Facts about 3-(1H-indol-3-yl)-2-(methylamino)propanoic Acid

3-(1H-indol-3-yl)-2-(methylamino)propanoic acid is a fascinating compound that draws attention in both pharmaceutical and biochemical research. This compound is particularly interesting for several reasons:

  • Biological Significance: The structure of this compound is closely related to tryptophan, an essential amino acid, and it exhibits potential as a neurotransmitter precursor, which could have implications for mood regulation and neuropharmacology.
  • Structure and Function: The compound contains an indole ring, which is common in a number of naturally occurring compounds, including serotonin and melatonin, both of which play crucial roles in regulating physiological functions such as sleep and mood.
  • Research Potential: Due to its unique chemical structure, researchers are investigating its properties for potential therapeutic applications in treating conditions like depression and anxiety.
  • Mechanism of Action: Studies suggest that compounds similar to this one may influence the serotonin pathways in the brain, further highlighting its relevance in the study of mental health.

Furthermore, the presence of the methylamino group enhances its ability to interact with biological molecules, making it a subject of interest for medicinal chemistry. As you can see, the compound's intricate structure and its potential biological effects make it an exciting area for ongoing research. As one scientist aptly stated, "The more we understand about compounds like 3-(1H-indol-3-yl)-2-(methylamino)propanoic acid, the closer we get to unlocking new pathways for therapeutic interventions."

Its study not only bridges the gaps in our knowledge of indole derivatives but also opens up avenues for developing novel pharmacological tools.

Synonyms
Tryptophan, N-methyl-
3-(1H-indol-3-yl)-2-(methylamino)propanoic acid
ABRINE (L)
N-methyltryptophan
487-59-2
n-methyl-d-tryptophan
N-Me-Trp-OH
MFCD00005645
N-Methyltryptophah
862504-05-0
methyl-dl-tryptophan
Spectrum_001182
SpecPlus_000633
Spectrum2_001996
Spectrum3_001529
Spectrum4_001849
Spectrum5_000358
DL-Tryptophan, N-methyl-
SCHEMBL18777
BSPBio_002918
KBioGR_002258
KBioSS_001662
DivK1c_006729
SPECTRUM1502236
SPBio_002211
CHEMBL2360657
CHEBI:93824
KBio1_001673
KBio2_001662
KBio2_004230
KBio2_006798
KBio3_002418
DTXSID40967027
HMS1921N12
BCP15809
MJB50405
CCG-39534
SDCCGMLS-0066711.P001
NCGC00094555-01
NCGC00094555-02
NCGC00094555-03
NCGC00094555-04
SY057298
EN300-1270334
3-(1H-indol-3-yl)-2-(methylamino)propanoicacid
AD-266/41884771
SR-05000002457
SR-05000002457-1
Abrine;N-Methyl-L-tryptophan;L-Tryptophan, N-methyl-
Q27165554