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imidazolylpyruvic acid

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Identification
Molecular formula
C6H6N2O3
CAS number
55757-30-7
IUPAC name
3-(1H-imidazol-5-yl)-2-oxo-propanoic acid
State
State

In its pure form, imidazolylpyruvic acid is a solid at room temperature. It has a crystalline structure that makes it relatively stable, although it can become amorphous in presence of moisture.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
154.12g/mol
Molar mass
154.1240g/mol
Density
1.4945g/cm3
Appearence

Imidazolylpyruvic acid is typically a white to off-white crystalline powder. It is known for being relatively hygroscopic, meaning it can absorb moisture from the environment, which can affect its appearance in humid conditions.

Comment on solubility

Solubility of 3-(1H-imidazol-5-yl)-2-oxo-propanoic acid (C6H6N2O3)

The compound 3-(1H-imidazol-5-yl)-2-oxo-propanoic acid exhibits interesting solubility characteristics due to its structural features. Here are some key points to consider:

  • Polar Nature: The presence of the carboxylic acid functional group contributes to the overall polarity of the molecule, enhancing its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The capability to form hydrogen bonds with water molecules facilitates its solubility. The –COOH group in particular plays a critical role in this interaction.
  • Solvent Compatibility: While it is soluble in polar solvents, it may have limited solubility in non-polar solvents, making it more selective in terms of solvation.
  • pH Dependence: The solubility of this compound might also vary with pH. In acidic conditions, the protonation of the imidazole ring can influence the aqueous solubility.

In conclusion, 3-(1H-imidazol-5-yl)-2-oxo-propanoic acid is generally more soluble in polar environments, establishing its utility in various applications requiring solubility in aqueous phases. Understanding its solubility behavior is paramount, as it can significantly impact its biological activity and interactions.

Interesting facts

Exploring 3-(1H-imidazol-5-yl)-2-oxo-propanoic acid

3-(1H-imidazol-5-yl)-2-oxo-propanoic acid is a fascinating compound that has garnered interest in various fields of chemistry, particularly in medicinal chemistry and biochemistry. Here are some interesting facts that highlight its significance:

  • Pharmacological Potential: This compound is of great importance due to its potential role as a pharmaceutical agent. Its structure featuring an imidazole ring is critical, as imidazole derivatives often display a wide range of biological activities, including antimicrobial and antifungal properties.
  • Biological Relevance: The imidazole moiety in the compound contributes to various biological processes. Compounds containing imidazole are known to function as enzyme inhibitors or as ligands in biological systems, making this compound a valuable substance for research into metabolic pathways.
  • Synthesis and Applications: Chemists have developed various methods for synthesizing this compound, often using straightforward organic reactions that can be adapted for large-scale production. Its ability to serve as an intermediate in the synthesis of more complex molecules is of significant interest for drug development.
  • Research Utility: 3-(1H-imidazol-5-yl)-2-oxo-propanoic acid is utilized not only in pharmacological studies but also in the research of ligand-receptor interactions and enzyme kinetics, making it a versatile tool in biochemistry labs.

As research continues, this compound may unlock new pathways toward therapeutic agents, reflecting the ongoing exploration of organic compounds within the realm of chemistry.

Synonyms
2504-83-8
3-(1H-imidazol-5-yl)-2-oxopropanoic acid
3-(1H-imidazol-4-yl)-2-oxopropanoic acid
Imidazole pyruvate
Imidazole pyruvic acid
imidazol-5-yl-pyruvate
3-(imidazol-5-yl)pyruvic acid
Imidazole-4-pyruvic acid
4-Imidazolylbrenztraubensaure
SCHEMBL1331769
3-(imidazol-4-yl)pyruvic acid
CHEBI:17406
CHEBI:59013
DTXSID00274284
AKOS006277771
3-(4-Imidazolyl)-2-oxopropionic acid
FI157399
3-(1H-imidazol-4-yl)-2-oxopropanoicacid
C03277
EN300-1819553