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Chlorophyllide a

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Identification
Molecular formula
C35H34N4O5
CAS number
11003-96-4
IUPAC name
3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic acid
State
State

At room temperature, chlorophyllide a is typically in a solid state. It can exist in crystalline form and is generally more stable in a dry environment, protected from light and oxygen to prevent degradation.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.15
General information
Molecular weight
613.96g/mol
Molar mass
613.9580g/mol
Density
1.1000g/cm3
Appearence

Chlorophyllide a typically appears as a bluish-green solid. This compound is derived from chlorophyll and is known for its vibrant color, which is a result of its distinctive conjugated double-bond structure that highly absorbs and reflects certain wavelengths of light.

Comment on solubility

Solubility of 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic acid

The solubility of the compound 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic acid, with the chemical formula C35H34N4O5, is influenced by several key factors:

  • Polarity: The presence of multiple functional groups, including the carboxylic acid moiety, enhances the compound's polarity, which can increase its solubility in polar solvents such as water.
  • Hydrophilic vs. Hydrophobic Balance: Although the carboxylic acid group contributes to hydrophilicity, the extensive presence of large hydrocarbon segments may limit solubility in aqueous environments.
  • Temperature's Role: Solubility can vary with temperature changes, often increasing as temperature rises, which is particularly crucial for organic compounds.
  • pH Influence: The solubility will also depend on the pH of the solution since the carboxylic acid can ionize at higher pH levels, potentially increasing aqueous solubility.

It is worth noting that compounds of this nature can exhibit markedly different solubility profiles under varying conditions. Therefore, understanding the context in which the solubility is measured is essential for accurate predictions and applications.

Interesting facts

Interesting Facts about 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic Acid

The compound known as 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic acid is a fascinating member of the porphyrin family, which are essential for numerous biological functions. Here are some intriguing aspects to explore:

  • Biological Significance: Porphyrins play critical roles in biological systems, prominently serving as co-factors in hemoglobin, chlorophyll, and cytochromes. This compound's structural configuration suggests it could have unique applications in photosynthesis and respiration studies.
  • Structure Complexity: The intricate design of this compound includes multiple vinyl and methyl substitutions, which can impact its reactivity and stability. The presence of a carboxylic acid group enhances its solubility in polar solvents, making it useful in various applications.
  • Potential Applications: Due to its structural similarities with naturally occurring porphyrins, this compound could be explored for uses in photodynamic therapy, where compounds are activated by light to destroy cancerous cells.
  • Synthesis Challenges: The synthesis of such complex molecules often involves multi-step processes, requiring advanced techniques in organic chemistry and significant expertise in managing stereo- and regioselectivity.
  • Research Opportunities: As various aspects of this compound are investigated, it opens the door to novel discoveries not only in organic synthesis but also in medicinal chemistry and materials science.

In summary, 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphyrin-2-yl]propanoic acid is much more than just a chemical formula. Its multifaceted structure holds promise for exciting research opportunities and potential applications in the realms of biochemistry and pharmacology. As noted by scientists in the field, "the complexity of porphyrins is matched only by their significance in nature."

Synonyms
protoporphyrin IX
protoporphyrin
553-12-8
Ooporphyrin
Protoporpyrin IX
Porphyrinogen IX
Kammerer's prophyrin
Protoporphyrin IX disodium
Protoporphyrin IX (VAN)
H2ppIX
CHEBI:15430
NSC2632
protoporphyrin-IX
NSC 2632
NSC-2632
3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid
EINECS 209-033-7
Kammerer's porphyrin
MLS001074731
3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-
21H,23H-Porphine-2,18-dipropanoic acid,7,12-diethenyl-3,8,13,17-tetramethyl-
C2K325S808
SMR000127405
3,3'-(3,7,12,17-Tetramethyl-8,13-divinylporphine-2,18-diyl)di(propionic acid)
PROTOPORPHYRIN IX [MI]
PROTOPORPHYRIN [WHO-DD]
DTXSID4048353
2,18-Porphinedipropionic acid, 3,8,13,17-tetramethyl-7,12-divinyl-
3,3'-(3,7,12,17-tetramethyl-8,13-divinyl-21H,23H-porphine-2,18-diyl)-bis-propionic acid
protoporphyrin ix containing fe
3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoic acid
7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoic acid
ProtoporphyrinIX
1,3,5,8-TETRAMETHYL-2,4-DIVINYLPORPHINE-6,7-DIPROPIONATE
3,3'-(3,7,12,17-tetramethyl-8,13-divinylporphine-2,18-diyl)di
3,3'-(3,7,12,17-tetramethyl-8,13-divinyl-21H,23H-porphine-2,18-diyl)-bis-propionate
SR-01000076084
UNII-C2K325S808
3-(18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl)propanoic acid
3-(20-(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo(16.2.1.13,6.18,11.113,16)tetracosa-1(21),2,4,6,8(23),9,11,13,15,17,19-undecaen-4-yl)propanoic acid
3-[20-(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.13,6.18,11.113,16]tetracosa-1(21),2,4,6,8(23),9,11,13,15,17,19-undecaen-4-yl]propanoic acid
protoporphyrin-"IX"
Spectrum_001300
Hem
Spectrum2_001016
Spectrum3_001440
Spectrum4_000419
Spectrum5_001303
cid_4971
Lopac0_000973
SCHEMBL25719
BSPBio_003180
KBioGR_000718
KBioSS_001780
Protoporphyrin IX, >=95%
DivK1c_000074
SCHEMBL805850
SPECTRUM1501111
SPBio_001171
SCHEMBL3287054
CHEMBL1325592
CHEMBL1618319
CHEMBL1907974
CHEMBL4463327
DTXCID5028328
SCHEMBL14552654
BDBM51757
CHEBI:26361
HMS500D16
KBio1_000074
KBio2_001780
KBio2_004348
KBio2_006916
KBio3_002400
FEDYMSUPMFCVOD-UHFFFAOYSA-N
KSFOVUSSGSKXFI-UHFFFAOYSA-N
KSFOVUSSGSKXFI-UJJXFSCMSA-N
NINDS_000074
OXTIQTUKEUGAPP-UJJXFSCMSA-N
ZCFFYALKHPIRKJ-UHFFFAOYSA-N
HMS1921F05
HMS2271B12
HMS3263C07
Pharmakon1600-01501111
HY-B1247
Tox21_500973
BDBM50523755
CCG-39673
NSC757839
AKOS027320494
CS-4849
DB02285
FP52448
LP00973
NSC-757839
SDCCGMLS-0066712.P001
SDCCGSBI-0050946.P004
IDI1_000074
NCGC00015844-01
NCGC00015844-02
NCGC00015844-03
NCGC00015844-04
NCGC00015844-05
NCGC00015844-07
NCGC00015844-08
NCGC00015844-12
NCGC00094273-01
NCGC00094273-02
NCGC00094273-03
NCGC00162303-01
NCGC00185010-01
NCGC00261658-01
AS-17461
SBI-0050946.P003
EU-0100973
protoporphyrin IX [MeSH: protoporphyrin IX]
2, 3,8,13,17-tetramethyl-7,12-divinyl-
C02191
C75594
P 8293
AB00052204_02
Q619815
SR-01000763747
SR-01000076084-1
SR-01000076084-4
SR-01000076084-5
SR-01000763747-3
BRD-K26813314-001-04-4
BRD-K26813314-001-08-5
21H,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-
3,18-Divinyl-2,7,13,17-tetramethylporphine-8,12-dipropionic acid
2,18-Porphinedipropionic acid, 3,8,13,17-tetramethyl-7,12-divinyl-(8CI)
2,18-Porphinedipropionic acid, 3,8,13,17-tetramethyl-7,12-divinyl- (8CI)
3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionic acid
3,3'-(7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropanoic acid
209-033-7
3-[(1Z,4Z,9Z,15Z)-18-(2-Carboxy-ethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-2-yl]-propionic acid
3-[(1Z,4Z,9Z,15Z)-18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-21,23-dihydroporphyrin-2-yl]propanoic acid
3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphin-2-yl]propionic acid
3-[18-(2-carboxyethyl)-3,8,13,17-tetramethyl-7,12-divinyl-21,23-dihydroporphyrin-2-yl]propanoic acid
3-[8,13-bis(ethenyl)-18-(3-hydroxy-3-oxopropyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid