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Phenazone

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Identification
Molecular formula
C17H16N2O2
CAS number
60-80-0
IUPAC name
3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione
State
State

At room temperature, phenazone is typically a solid.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
182.00
Boiling point (Kelvin)
455.15
General information
Molecular weight
284.33g/mol
Molar mass
284.3370g/mol
Density
1.1993g/cm3
Appearence

Phenazone is a white or almost white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione (C17H16N2O2)

The solubility characteristics of the compound 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione can be quite intriguing due to its complex structure. In general, solubility depends on several factors including polarity, molecular size, and the presence of functional groups. For this particular compound, the following points can be considered:

  • Polarity: The presence of both nitrogen and oxygen atoms suggests potential polar characteristics, which may enhance the solubility in polar solvents.
  • Hydrophobic interactions: The benzyl group introduces hydrophobic properties, which can reduce solubility in water but may favor solubility in organic solvents.
  • Solvent dependence: This compound may exhibit different solubility profiles in various solvents. For instance, it could be more soluble in alcohols or dimethyl sulfoxide (DMSO) than in water.
  • Concentration: As with many organic compounds, the degree of solubility can also vary with concentration; higher concentrations might lead to decreased solubility due to saturation effects.

In summary, while definitive solubility data may not be readily available, one can posit that 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione exhibits a nuanced solubility profile. It is essential to consider the appropriate solvent for desired applications, and conducting empirical solubility tests can provide valuable insights.

Interesting facts

Interesting Facts about 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione

This compound, known for its intricate structure, is a member of the pyrrolidine class of compounds, which are known to exhibit a variety of biological activities. Here are some fascinating insights:

  • Pharmacological Potential: Compounds similar to 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione have been studied for their potential in medicinal chemistry, particularly in the development of drugs to combat cancer and other diseases.
  • Diverse Reactivity: The presence of the dione functionality allows for a wide range of chemical reactivity, making it a versatile building block in organic synthesis. This feature can be exploited to create various derivatives and analogs.
  • Structural Features: The unique combination of the pyrrolidine ring and the anilino group provides *steric* and *electronic* diversity, which can significantly influence the biological activity of the compound.
  • Interdisciplinary Interest: This compound bridges the fields of organic chemistry, medicinal chemistry, and even materials science, as researchers are continually looking for innovative applications in drug design and development.
  • Research Applications: Scientists are investigating its role as a potential lead compound in synthesizing more complex molecules that may exhibit enhanced activity in biological systems.

As a compound that highlights the *intersection of structure and function*, 3-(1-anilinoethylidene)-5-benzyl-pyrrolidine-2,4-dione serves as a perfect example of the exciting possibilities within synthetic organic chemistry.