Skip to main content

L-aspartic acid

ADVERTISEMENT
Identification
Molecular formula
C4H7NO4
CAS number
56-84-8
IUPAC name
(2S)-2,4-diamino-4-oxo-butanoic acid
State
State

At room temperature, L-aspartic acid is in a solid state. It is insoluble in water but is soluble in alcohol, reflecting its dual acidic and basic properties that categorize it as an amino acid. This solid-state is typical for amino acids under standard conditions of temperature and pressure.

Melting point (Celsius)
270.00
Melting point (Kelvin)
543.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
133.10g/mol
Molar mass
133.1030g/mol
Density
1.6600g/cm3
Appearence

In its pure form, L-aspartic acid is a white crystalline powder. The compound is odorless and has a slightly sweet taste. It is a non-essential amino acid, which is colorless or white and has a high melting point, indicating its crystalline nature.

Comment on solubility

Solubility of (2S)-2,4-diamino-4-oxo-butanoic acid (C4H7NO4)

(2S)-2,4-diamino-4-oxo-butanoic acid is an intriguing compound known for its distinctive structure and the presence of several functional groups that can influence its solubility characteristics. The solubility of this compound is largely determined by the following factors:

  • Polarity: Due to its amino (-NH2) and carboxylic acid (-COOH) functional groups, the compound exhibits high polarity, which generally enhances its solubility in water.
  • Hydrogen Bonding: The presence of multiple sites for hydrogen bonding allows for effective interaction with solvent molecules, further contributing to its aqueous solubility.
  • pH Dependence: As a carboxylic acid, the solubility can vary with pH levels, with increased solubility observed in alkaline conditions when deprotonation occurs, enhancing its ability to interact with polar solvents.

In summary, "(2S)-2,4-diamino-4-oxo-butanoic acid is likely to be soluble in water due to its polar nature and ability to form hydrogen bonds." However, evaluating its solubility across various solvents can provide deeper insights into its behavior in different chemical environments.

Interesting facts

Interesting Facts about (2S)-2,4-diamino-4-oxo-butanoic acid

(2S)-2,4-diamino-4-oxo-butanoic acid is a fascinating compound, primarily due to its role as an important intermediate in the synthesis of various biological molecules. Often abbreviated as DABA, it is a derivative of amino acids and plays a significant role in metabolic pathways. Below are some compelling aspects linked to this compound:

  • Biological Relevance: DABA is involved in the biosynthesis of certain amino acids, specifically in the biosynthetic pathways that lead to the production of important nutrients.
  • Potential Therapeutic Uses: Due to its structural features, researchers have been exploring DABA for potential therapeutic applications, especially concerning metabolic disorders.
  • Enzymatic Reactions: DABA can act as a substrate for various enzymes, making it a pivotal compound in enzymatic research and metabolic engineering.
  • Structural Diversity: The presence of both amino and oxo functional groups in DABA adds to its diversity, helping scientists to study the effects of structural changes in biochemical processes.
  • Synthesis of Derivatives: DABA serves as a precursor for more complex compounds, which can be synthesized to explore new pharmaceuticals and bioactive molecules.

Notably, understanding the properties and reactions of (2S)-2,4-diamino-4-oxo-butanoic acid continues to be paramount in the field of organic chemistry and biochemistry. As stated by one researcher, "Compounds like DABA remind us of the intricate connections between chemistry and life itself." Its multifaceted nature keeps it relevant for ongoing studies and innovative applications.

Synonyms
L-asparagine
asparagine
70-47-3
H-Asn-OH
(S)-asparagine
Aspartamic acid
agedoite
altheine
Asparamide
Crystal VI
asparagine acid
(S)-2,4-diamino-4-oxobutanoic acid
Asparagine, L-
(-)-asparagine
L-Asparagine anhydrous
L-Aspartamine
alpha-aminosuccinamic acid
2-Aminosuccinamic acid
L-2,4-diamino-4-oxobutanoic acid
aspartic acid beta-amide
Asparagine anhydrous
L-asparatamine
(2S)-2-amino-3-carbamoylpropanoic acid
ASN
L-b-Asparagine
(2S)-2,4-diamino-4-oxobutanoic acid
Asparagine (VAN)
Aspartic acid amide
2-aminosuccinamic acid, L-
butanoic acid, 2,4-diamino-4-oxo-, (S)-
L-2-aminosuccinamic acid
L-Asparagin
7NG0A2TUHQ
L-beta-Asparagine (VAN)
L-aspartic acid beta-amide
L-beta-asparagine
MFCD00064401
NSC 82391
L-Asn
5Z33R5TKO7
2,4-diamino-4-oxobutanoic acid, (S)-
CHEBI:17196
HSDB 7425
EINECS 200-735-9
NSC-82391
(S)-2-amino-3-carbamoylpropanoic acid
UNII-5Z33R5TKO7
Nor Benzphetamine Hydrochloride
L-?Asparagine
DTXSID10883220
Aminoplasmal
Normofundin
Nutrifundin
Thomaeamin
(S)-2-Aminosuccinic acid 4-amide
asparagina
L-Asparagin-1-wasser
Hasp
UNII-2PD79VF521
ASPARAGINE ANHYDROUS (USP-RS)
ASPARAGINE ANHYDROUS [USP-RS]
L-(+)-Asparagine
L-.beta.-Asparagine
Aspartic acid b-amide
a-Aminosuccinamic acid
NSC 760099
Nor Benzphetamine Hydrochloride (1.0mg/ml in Methanol)
CHEBI:22653
aspargine
Aspartamate
(-)-Asparagine; Asn; Asparamide
a-Aminosuccinamate
2-Aminosuccinamate
a-?ethyl-N-(phenylmethyl)benzeneethanamine Hydrochloride; N-?enzyl-a-methylphenethylamine ?ydrochloride;
Asn-OH
alpha-Aminosuccinamate
4-imino-L-homoserine
alpha Amminosuccinamate
L-Asparagine (9CI)
H-Asn-OH H
ASPARAGINE [MI]
Aspartic acid beta amide
L-Asparagine (Standard)
N-Lauryl-N-methyltaurine
ASPARAGINE [HSDB]
alpha Amminosuccinamic acid
Asparagine, L- (8CI)
bmse000030
bmse000912
Aspartic acid .beta. amide
L-ASPARAGINE [FCC]
L-Asparagine (H-Asn-OH)
ASPARAGINE [WHO-DD]
.alpha.-Aminosuccinamic acid
L-(+)-Asparagine anhydrous
CHEMBL58832
ASPARAGINE (L) HYDRATE
(-)-Asparagine;Asn;Asparamide
GTPL4533
SCHEMBL3126352
L-2,4-Diamino-4-oxobutanoate
US9138393, L-Asparigine
US9144538, L-Asparigine
HY-N0667R
BDBM181137
DTXCID901022769
Pharmakon1600-01301002
(S)-2,4-Diamino-4-oxobutanoate
L-Asparagine, >=98% (HPLC)
HY-N0667
STR07164
B2,4-(S)-diamino-4-oxo-utanoate
NSC760099
s5571
AKOS006239067
AC-4657
CCG-266117
DB00174
FA16019
NSC-760099
B2,4-(S)-diamino-4-oxo-utanoic acid
NCGC00344576-01
BP-23453
A0542
A3353
CS-0009702
NS00002372
EN300-67209
L-Asparagine, Vetec(TM) reagent grade, 98%
C00152
M02998
BRD-K06665116-001-02-6
Q29519883
F1905-7151
Z1066276474
3C28F6A9-E581-4255-ACCF-F75597AB288F
L-Asparagine, certified reference material, TraceCERT(R)
L-Asn-OH;L-Aspartic acid 4-amide;(S)-2-Aminosuccinic acid 4-amide
Asparagine anhydrous, United States Pharmacopeia (USP) Reference Standard
L-Asparagine, BioReagent, suitable for cell culture, suitable for insect cell culture
200-735-9