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Pseudoephedrine

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Identification
Molecular formula
C10H15NO
CAS number
90-82-4
IUPAC name
(2S)-2-(methylamino)-1-phenyl-propan-1-ol
State
State

At room temperature, pseudoephedrine is typically in a solid state.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
191.00
Boiling point (Kelvin)
464.15
General information
Molecular weight
165.24g/mol
Molar mass
165.2370g/mol
Density
0.9800g/cm3
Appearence

Pseudoephedrine typically appears as a white, crystalline powder. It may also be found as a solid crystalline substance in pharmaceuticals.

Comment on solubility

Solubility of (2S)-2-(methylamino)-1-phenyl-propan-1-ol

The solubility of (2S)-2-(methylamino)-1-phenyl-propan-1-ol, a chiral alcohol, is an intriguing topic that highlights the interplay between molecular structure and solvent interactions. This compound, possessing both hydrophilic and hydrophobic characteristics, tends to exhibit diverse solubility behavior based on the solvent used. Here are some key points regarding its solubility:

  • Polar solvents: This compound is likely to show good solubility in polar solvents such as water, due to the presence of the hydroxyl group (-OH) and the polar amino group.
  • Non-polar solvents: Conversely, (2S)-2-(methylamino)-1-phenyl-propan-1-ol may exhibit significantly lower solubility in non-polar solvents, reflecting its aromatic phenyl group.
  • Temperature effects: The temperature can also influence solubility, with increased temperatures generally enhancing solute dissolution in solvents.
  • pH dependence: Changes in pH can affect the ionization state of the amino group, potentially increasing solubility in acidic or basic environments compared to neutral conditions.

In summary, the solubility of (2S)-2-(methylamino)-1-phenyl-propan-1-ol is a function of several factors, making it essential to consider both the solvent characteristics and environmental conditions when predicting its solubility in various applications.

Interesting facts

Interesting Facts About (2S)-2-(Methylamino)-1-phenyl-propan-1-ol

(2S)-2-(Methylamino)-1-phenyl-propan-1-ol, often referred to in various contexts, is a fascinating compound in the realm of organic chemistry. It is particularly noteworthy for its role as a chiral pharmaceutical intermediate, significantly impacting the drug development process. Here are some intriguing aspects:

  • Chirality: This compound exhibits chirality, meaning it has non-superimposable mirror images. This property is critical in pharmacology because the different enantiomers can have vastly different biological activities.
  • Pharmaceutical Relevance: Due to its structure, it can act as a precursor to various pharmaceuticals. The presence of both an amino group and an alcohol group contributes to its reactivity, making it a versatile building block in synthetic chemistry.
  • Molecular Interactions: The hydroxyl and amino groups enable this compound to engage in hydrogen bonding, influencing its solubility and interaction with biological macromolecules, thereby affecting drug efficacy and safety.
  • Synthesis Pathways: The synthesis of this compound can involve multiple strategies, including asymmetric synthesis, which is crucial when creating enantiomerically pure substances that reduce unwanted side effects in drugs.
  • Potential Applications: Beyond pharmaceuticals, research is ongoing to explore its potential uses in other fields, such as agrochemicals or as intermediates in developing new materials.

In summary, (2S)-2-(methylamino)-1-phenyl-propan-1-ol stands as a testament to the complexities and wonders of organic chemistry, reflecting how molecular structure not only dictates function but also impacts human health and technology. As noted by scientists in the field, "Understanding the intricacies of chiral molecules like this is essential in striving for innovation in drug design."

Synonyms
CHEMBL357080
SCHEMBL2633794
l-1-phenyl-2-methylaminopropanol