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Testosterone

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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
State
State
Testosterone is typically in a solid state at room temperature, taking a crystalline powder form.
Melting point (Celsius)
155.00
Melting point (Kelvin)
428.00
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.00
General information
Molecular weight
288.43g/mol
Molar mass
288.4310g/mol
Density
1.1200g/cm3
Appearence

Testosterone generally appears as a white or whitish crystalline powder. When exposed to air, it is stable and does not change rapidly in appearance. It can appear as colorless crystals as well.

Comment on solubility

Solubility of 17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one (C19H28O2)

The solubility of this complex organic compound, known for its intricate structure, is of great interest in various scientific applications. Understanding the solubility characteristics can provide insights into its behavior in different environments. Let's delve deeper into the factors influencing its solubility:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents, whereas the hydrocarbon structure suggests limited solubility in water.
  • Solvent Interactions: While it may dissolve better in organic solvents like ethanol or chloroform, it may have poor solubility in water due to hydrophobic interactions.
  • Temperature Effects: Increasing temperature usually increases solubility for solid compounds, potentially leading to a higher prevalence of the compound in solution at elevated temperatures.
  • Concentration Dependence: Solubility can vary based on concentration levels, influencing the rate of dissolution and the establishment of equilibrium.

In summary, the solubility of C19H28O2 is greatly influenced by factors such as polarity, solvent types, temperature, and concentration. Understanding these facets not only helps in predicting its behavior in biological systems but also informs its practical applications in pharmacology and organic chemistry. As with many organic compounds, exploring the nuances of solubility can uncover new potential pathways for research and utilization.

Interesting facts

Interesting Facts about (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

This complex compound, often referred to within the realms of organic chemistry and biochemistry, is part of a fascinating class of molecules known as steroids. In particular, it showcases a unique molecular structure characterized by a tetradecahydrocyclopenta[a]phenanthren backbone, which contributes to its intricate physical and chemical properties.

Key Features and Relevance

  • Biological Significance: This compound is notable for its role as a steroid hormone, which means it may influence a variety of physiological processes including metabolism, immune function, and reproductive health.
  • Stereochemistry: The configuration of this compound is crucial. The specific arrangement of its multiple chiral centers (denoted by the R and S designations) contributes to its biological activity and interactions with receptors.
  • Potential Applications: Compounds with similar structures have been studied for their therapeutic potential. For instance, they can act as anti-inflammatory agents or hormone replacements in hormone therapy.
  • Research and Investigation: Ongoing studies often focus on how such compounds can be synthesized and modified to enhance their efficacy, reduce side effects, or improve their stability.
  • Historical Context: The discovery and analysis of steroid compounds have significantly impacted fields such as pharmacology, endocrinology, and even sports medicine, as these molecules are often at the center of discussions surrounding anabolic steroids.

As with many complex organic molecules, understanding this compound involves not just structural analysis but also a deep dive into its biochemical interactions and physiological implications. In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” The study of compounds like this one opens doors to a multitude of possibilities in science and medicine.

Synonyms
dromostanolone
Drostanolone
Metholone
Medrotestron
Medrosteron
58-19-5
Drostanolona
Drostanolonum
2alpha-Methyldihydrotestosterone
Drostanolo [DCIT]
Drostanolo
Methalone
Dihydro-2alpha-methyltestosterone
Drostanolone [INN:BAN]
Drostanolonum [INN-Latin]
Drostanolona [INN-Spanish]
SKI 27719
CCRIS 2777
2-alpha-Methyldihydrotestosterone
HSDB 3319
Dihydro-2-alpha-methyltestosterone
EINECS 200-367-9
7DR7H00HDT
CHEBI:34838
AI3-52812
5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-
Testosterone, 4,5alpha-dihydro-2alpha-methyl-
DROSTANOLONE [INN]
DROMOSTANOLONE [MI]
DROSTANOLONE [HSDB]
17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one
DROSTANOLONE [WHO-DD]
17-beta-Hydroxy-2-alpha-methyl-5-alpha-androstan-3-one
2-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one
5alpha-Androstan-3-one, 17beta-hydroxy-2alpha-methyl-
DTXSID6022971
2.alpha.-Methyldihydrotestosterone
Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)-
Androstan-3-one, 17-hydroxy-2-methyl-, (2-alpha,5-alpha,17-beta)-
NSC26198
Drostanolonum (INN-Latin)
Drostanolona (INN-Spanish)
drostanolon
prometholone
(2alpha,5alpha,17beta)-17-hydroxy-2-methylandrostan-3-one
5.alpha.-Androstan-3-one, 17.beta.-hydroxy-2.alpha.-methyl-
(2.ALPHA.,5.ALPHA.,17.BETA.)-17-HYDROXY-2-METHYLANDROSTAN-3-ONE
Androstan-3-one, 17-hydroxy-2-methyl-, (2.alpha.,5.alpha.,17.beta.)-
(1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
Drostanolone (1.0 mg/mL in Acetonitrile)
UNII-7DR7H00HDT
Dihydro-2.alpha.-methyltestosterone
(1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo(8.7.0.0^(2,7).0^(11,15))heptadecan-5-one
(1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo(8.7.0.02,7.011,15)heptadecan-5-one
(1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-one
CHEMBL1582
SCHEMBL19561
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
DTXCID502971
17 beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one
2 Alpha-methyldihydrotestosterone
TQP0581
IKXILDNPCZPPRV-RFMGOVQKSA-N
DB00858
2alpha-methylandrostan-17beta-ol-3-one
2 Alpha-methylandrostan-17 beta-ol-3-one
NS00033880
2|A-Methyl-17|A-hydroxy-5|A-androstan-3-one
Testosterone,5.alpha.-dihydro-2.alpha.-methyl-
Q422343
2 Alpha-5 alpha-17 beta-17-hydroxy-2-methyl-androstan-3-one
Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)-(9CI)
200-367-9