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Adenosine Triphosphate

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Identification
Molecular formula
C10H16N5O13P3
CAS number
56-65-5
IUPAC name
[[(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
State
State
Adenosine Triphosphate is solid at room temperature and is commonly found in the form of its salt or complex in biological systems.
Melting point (Celsius)
156.00
Melting point (Kelvin)
429.00
Boiling point (Celsius)
190.00
Boiling point (Kelvin)
463.00
General information
Molecular weight
507.18g/mol
Molar mass
507.1810g/mol
Density
1.6500g/cm3
Appearence

Adenosine Triphosphate, commonly known as ATP, is an organic compound that is often discussed in the context of biochemistry. ATP in its pure form is a white crystalline powder. In biological systems, ATP is present as aqueous solutions in cells and tissues.

Comment on solubility

Solubility Overview

The compound [(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl phosphono hydrogen phosphate, with the chemical formula C10H16N5O13P3, presents intriguing properties regarding its solubility.

Factors Influencing Solubility

Several characteristics dictate the solubility of this compound:

  • Polarity: Given its numerous hydroxyl (–OH) and phosphoryl (–PO4) groups, the compound is likely to be polar, enhancing its solubility in aqueous solutions.
  • Hydrogen Bonding: The presence of both amino and hydroxyl groups suggests significant hydrogen bonding capabilities, which can favorably interact with water molecules.
  • Molecular Structure: The intricate arrangement of its tetrahydrofuran ring and associated functional groups could lead to unique solubility behaviors depending on the solvent used.

Expected Solubility Behavior

While precise solubility data may be limited, one could anticipate:

  • High solubility in polar solvents such as water, due to its extensive hydrogen bonding.
  • Potentially reduced solubility in organic solvents, attributable to its polar character.
  • Variability in solubility contingent on pH, as the presence of acidic or basic conditions could alter the ionization state of functional groups.

In summary, the solubility of this compound is predominantly influenced by its polar features and hydrogen bonding potential, making it an interesting subject for further investigation in various solvent systems.

Interesting facts

Understanding [(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl phosphono hydrogen phosphate

This compound, which we often refer to as a complex organophosphate, showcases fascinating structural features and potential applications in various fields. The diverse interactions arising from its multiple functional groups make it particularly interesting to chemists and biochemists alike.

Key Features

  • Chirality: The designated stereochemistry (2R,3S,4R,5R) indicates specific spatial arrangements that can affect biological activity and binding interactions.
  • Pyrimidine Derivative: The presence of 4-amino-2-oxo-pyrimidine lends biological significance, as pyrimidines are foundational components in nucleotide and nucleic acid structure.
  • Phosphorylation: The phosphoryl group contributes to energy transfer processes in biological systems, analogous to adenosine triphosphate (ATP).
  • Potential Therapeutic Uses: Compounds with similar frameworks often exhibit antimicrobial or antitumor properties, suggesting avenues for further research in pharmacology.

Applications

Given its complex molecular architecture, this compound may hold promise in:

  • Drug Development: Its structural features might lead to the design of novel therapeutic agents.
  • Biochemistry Research: Understanding how it interacts with proteins and nucleic acids could provide insights into fundamental biological processes.
  • Biotechnology: Potential applications in enzyme catalysis and biosensors are worth exploring, particularly due to its phosphonate group.

The intricacies of this compound highlight the beauty of chemistry, where modifications at a molecular level can profoundly influence biological outcomes. As we continue to study and explore organophosphate derivatives, we unlock new possibilities for advancing science and improving human health.

Synonyms
Cytidine triphosphate
cytidine-5'-triphosphate
65-47-4
Cytidine 5'-(tetrahydrogen triphosphate)
Cytidine 5'-triphosphate
5'-CTP
Deoxycytosine triphosphate
CTP
Cytidine 3'-triphosphate
Cytidine 5'-triphosphoric acid
123334-07-6
BRN 0071190
H4ctp
EINECS 200-611-4
Cystetine Triphosphate
CHEBI:17677
K0118UX80T
Brain-1 protein, mouse
Rubella E1 envelope protein
81012-87-5
[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
ARA-CYTIDINE TRIPHOSPHATE
DTXSID70889324
4-25-00-03676 (Beilstein Handbook Reference)
Cytidine, mono(tetrahydrogen triphosphate) (ester)
CYTIDINE TRIPHOSPHATE [WHO-DD]
131016-01-8
147258-10-4
({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
CRPPP
Triphosphate, Cytidine
Cytidine mono
UNII-K0118UX80T
1wvc
(((((((2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)phosphonic acid
Cytidine5'-(tetrahydrogentriphosphate)
Cytidine5'triphosphate
2ad5
Cytidine 3'triphosphate
Cytidine 5' Triphosphate
bmse000277
5'CTP
Cytidine 5'triphosphoric acid
Cytidine 5-Prime-Triphosphate
SCHEMBL104629
CHEMBL223533
GTPL1741
SCHEMBL25201848
PCDQPRRSZKQHHS-XVFCMESISA-N
DTXCID101028587
BDBM50454133
AKOS016843990
DB02431
Cytidine 5'(tetrahydrogen triphosphate)
5'-(tetrahydrogen triphosphate) cytidine
Cytidine-5'-(tetrahydrogen triphosphate)
((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
[[(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
HY-125818
CS-0100072
5 inverted exclamation marka-CTP pound not3Na
C00063
CYTIDINE-5/'-TRIPHOSPHATE DISODIUM SALT
F82425
Cytidine mono(tetrahydrogen triphosphate) (ester)
CYTIDINE, 5'-(TETRAHYDROGEN TRIPHOSPHATE)
Q409648
Cytidine 5'-(tetrahydrogen triphosphate) (8CI,9CI)
[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
[[[(2R,3S,4R,5R)-5-(4-Amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid
2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-.beta.-D-ribofuranosyl]-
200-611-4