Skip to main content

Uridine monophosphate

ADVERTISEMENT
Identification
Molecular formula
C9H13N2O9P
CAS number
58-97-9
IUPAC name
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, this compound is typically a solid. Its crystalline powder form makes it somewhat stable under ambient conditions.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
324.18g/mol
Molar mass
324.1810g/mol
Density
2.1900g/cm3
Appearence

This compound appears as a white to off-white crystalline powder. It is often found in a dried form and can exist as a crystalline solid under proper conditions.

Comment on solubility

Solubility of [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The solubility of the compound with the formula C9H13N2O9P can be quite complex due to its intricate structure and the presence of functional groups. Understanding its solubility behavior is essential for practical applications in pharmaceuticals and biochemistry. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl (–OH) groups and the phosphate (–PO4) moiety in the molecule increases overall polarity, which generally enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds plays a significant role. The hydroxyl groups can interact with water molecules, contributing to increased solubility.
  • Salts and Derivatives: If considering solubility in different contexts, the formation of salts or its derivates may significantly alter solubility properties. For example, protonation of the phosphate group can lead to enhanced solubility in aqueous solutions.

Overall, the compound is likely to exhibit high solubility in polar solvents primarily due to the presence of both hydrophilic groups and charged entities. Researching the specific solubility profile using experimental data is crucial to ascertain precise values, as computational predictions may not capture all intermolecular interactions.

Interesting facts

Interesting Facts about [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This complex compound, often referred to as a nucleobase analog, holds significant interest in the field of medicinal chemistry and biochemistry due to its structural similarity to naturally occurring biological molecules. Here are some noteworthy aspects:

  • Nucleotide Analog: The presence of the pyrimidine ring in its structure suggests it may play a role in the synthesis of nucleotides, which are the building blocks of nucleic acids like DNA and RNA.
  • Potential Antiviral Activity: Compounds with structural similarities to pyrimidines often exhibit antiviral properties, making this compound a candidate for further research in antiviral drug development.
  • Role in Drug Design: Given its unique stereochemistry, it serves as a valuable model for studying drug interactions with target enzymes and receptors, particularly those involved in nucleic acid metabolism.
  • Phosphate Group Influence: The presence of the dihydrogen phosphate moiety is critical, as it can influence both the solubility and biological activity of the compound in living systems.

The intricate design of this compound highlights the elegance of molecular synthesis in producing biologically relevant structures. As emphasized by renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” This compound’s design exemplifies the essence of innovation in chemistry, pushing the boundaries of how we understand and interact with biological systems.

Research continues to explore the potential applications and mechanisms of such compounds, making this a fascinating topic for anyone interested in the intersection of chemistry and biology.

Synonyms
Uridine 5'-monophosphate
5'-URIDYLIC ACID
58-97-9
Uridylic acid
Uridine monophosphate
uridine-5'-monophosphate
Uridine phosphate
Uridine 5'-phosphate
Uridine 5'-phosphoric acid
5'-UMP
UMP
UMP (nucleic acid)
uridylate
Uridine 5'-(dihydrogen phosphate)
5'Uridylic acid
Uridylicacid
CHEBI:16695
BRN 0047486
UNII-E2OU15WN0N
EINECS 200-408-0
E2OU15WN0N
MFCD00067346
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
CHEMBL214393
5-24-06-00173 (Beilstein Handbook Reference)
U 5'-P
{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Uridylic Acids
2,4(1H,3H)-pyrimidinedione, 1-(5-O-phosphono-beta-D-ribofuranosyl)-
Acids, Uridylic
Acid, Uridylic
((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
U5P
5'-uridylic acid (8CI)(9CI)
C9H13N2O9P
Monophosphate, Uridine
27416-86-0
5'-Monophosphate, Uridine
uridine-phosphate
URIDINE 5' MONOPHOSPHATE
1loq
5'-ridylic acid
uridine-monophosphate
UridylsA currencyure
5'-Uridylic acid,
uridine-5'-phosphate
Uridylic acid (6CI)
1xz8
Uridine 5'-phosphorate
5'-Uridylic acid; UMP
bmse000280
Epitope ID:196258
SCHEMBL157644
GTPL5125
5'-URIDYLIC ACID [MI]
DTXSID20883211
MSK6906
Uridine mono(dihydrogen phosphate)
URIDINE PHOSPHATE [WHO-DD]
Uridine-5'-(dihydrogen phosphate)
BDBM50398699
s9451
Uridine 5'-monophosphate (Standard)
AKOS016009839
DB03685
HY-101981R
NU05691
NCGC00163325-01
AC-32138
AS-56739
BP-58611
HY-101981
CS-0022391
Uridine, mono(dihydrogen phosphate) (ester)
UMP;Uridylic acid;D-Uridine 5'-monophosphate
C00105
F20483
Uridine 5 inverted exclamation marka-monophosphate
Q27074278
954D2AA9-0360-4F63-A7BF-63254220F1F3
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
200-408-0