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Uridine diphosphate glucose

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Identification
Molecular formula
C15H24N2O17P2
CAS number
133-89-1
IUPAC name
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate
State
State

Uridine diphosphate glucose is commonly found as a solid at room temperature. It can be in crystalline form or as a powder depending on its isolation and purification process. The compound is stable in solid form when stored appropriately, usually under dry conditions to prevent moisture absorption.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
566.31g/mol
Molar mass
566.3070g/mol
Density
1.7000g/cm3
Appearence

Uridine diphosphate glucose is typically a white to off-white solid. It is a hygroscopic compound and often appears as a powder when isolated. In its hydrated forms, it may appear slightly different, absorbing moisture from the atmosphere.

Comment on solubility

Solubility of the Compound

This intricate compound, known as the (2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl methoxy-hydroxy-phosphoryl [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate, exhibits complex solubility characteristics. Understanding its solubility can provide insights into its potential applications in various fields.

Key Points on Solubility:

  • Hydrophilicity: Due to the presence of multiple hydroxy groups (-OH) and a phosphate group, this compound is likely to be hydrophilic, enhancing its solubility in polar solvents like water.
  • pH Dependency: The solubility may vary with pH; under acidic or basic conditions, the ionization of the functional groups could influence solubility.
  • Temperature Effects: As with many compounds, an increase in temperature may lead to increased solubility, particularly in aqueous solutions.
  • Solvent Compatibility: This compound may display different solubilities in various solvents, highlighting the importance of choosing the right solvent for applications or experiments.

In conclusion, the solubility of this compound hinges on its intricate structure and functional groups, making it a fascinating subject for further study. As stated, “The solubility and behavior of a compound in solution can reveal much about its potential uses and interactions in biochemical processes.”

Interesting facts

Interesting Facts about a Unique Chemical Compound

This particular compound, with its complex structure, is a fascinating example of how nature has evolved functional molecules that play crucial roles in biochemistry. Here are some interesting facts about it:

  • Biological Significance: The compound is believed to be involved in essential biological processes, particularly in the realm of nucleic acid metabolism. Its structural components allow it to interact with various biological molecules, influencing their function.
  • Mechanism of Action: This compound may act through mechanisms that involve phosphorylation, which is a critical process for the regulation and activation of proteins and enzymes within cells.
  • Synthetic Challenges: The synthesis of such complex molecules is often a challenge in organic chemistry, requiring advanced techniques and an understanding of stereochemistry to ensure the correct configuration of chiral centers.
  • Potential Applications: Given its intricate structure, researchers are investigating possible applications in drug development, particularly in targeting specific pathways in cancer treatment and other diseases where cellular regulation is disrupted.
  • Structural Insights: The presence of hydroxyl groups in its configuration suggests that it may engage in hydrogen bonding, enhancing its solubility and reactivity in aqueous environments.
  • Historical Context: Compounds with similar features have historically been pivotal in the development of pharmaceuticals, highlighting the connection between chemical structure and biological activity.

In essence, this compound serves as a compelling example of the intersection between chemistry and biology, leading to insights that could pave the way for innovative therapeutic strategies.

Synonyms
UDP-glucose
URIDINE DIPHOSPHATE GLUCOSE
133-89-1
UDPG
UDP-alpha-D-Glucose
UDP-a-D-Glucose
co-waldenase
UDPglucose
URIDINE-5'-DIPHOSPHATE-GLUCOSE
co-galactoisomerase
Uridine diphosphoglucose
Cogalactoisomerase
UDP glucose
5'-Diphosphoglucose
Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester
URIDINE-5'-DIPHOSPHOGLUCOSE
Uridine diphospho-D-glucose
UDP-Glc
UNII-V50K1D7P4Y
Uridine pyrophosphate-glucose
Diphosphate Glucose, Uridine
Uridine 5'-diphosphoglucose
Uridine 5'-diphosphate glucose
V50K1D7P4Y
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
CHEBI:46229
EINECS 205-121-4
UDP-glucose Disodium Salt
Uridine 5'-diphospho-alpha-D-glucose
Uridine diphosphate-glucose
Uridine 5'-pyrophosphate glucose ester
DTXSID00157902
COGALACTOISOMERASE [WHO-DD]
URIDINE DIPHOSPHATE GLUCOSE [MI]
URIDINE DIPHOSPHATE GLUCOSE [WHO-DD]
Uridine 5'-(alpha-D-glucopyranosyl pyrophosphate)
GLUCOSE-URIDINE-C1,5'-DIPHOSPHATE
uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen diphosphate]
Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D-GLUCOPYRANOSYL ESTER
Glucose, UDP
Diphosphoglucose, Uridine
Glucose, Uridine Diphosphate
uridine 5'-(3-alpha-D-glucopyranosyl dihydrogen diphosphate)
(UDP)glucose
UDP-delta-glucose
(UPD)-glucose
(((2r,3s,4r,5r)-3,4-dihydroxy-5-(4-hydroxy-2-oxopyrimidin-1-yl)oxolan-2-yl)methoxy(hydroxy)phosphoryl)oxy(((3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)phosphinic acid
{[(2r,3s,4r,5r)-3,4-dihydroxy-5-(4-hydroxy-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy([(3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy)phosphinic acid
Uridindiphosphoglucose
Mono-D-glucosyl ester
UDP-alpha-delta-Glucose
5''''-Diphosphoglucose
SCHEMBL454078
Uridine diphospho-delta-glucose
CHEMBL375951
GTPL1783
DTXCID8080393
Uridine-5''''-Diphosphoglucose
Uridine 5'-diphospho-a-D-glucose
URIDINE-5'-MONOPHOSPHATE GLUCOPYRANOSYL-MONOPHOSPHATE ESTER
Uridine 5-(trihydrogen diphosphate)
BDBM50209659
BDBM50423218
Uridine 5'-diphospho-I+--D-glucose
AKOS040744389
URIDINE-5'-diphosphoric acid-glucose
DB01861
Uridine 5'-diphospho-alpha-delta-glucose
GLUCOSE-uridine-C1,5'-diphosphoric acid
C00029
G64794
Q424649
Uridine 5'-(I+--D-glucopyranosyl pyrophosphate)
Uridine 5'-pyrophosphate a-D-glucopyranosyl ester
Uridine 5'-pyrophosphate a-delta-glucopyranosyl ester
uridine 5''-[3-alpha-D-glucopyranosyl dihydrogen diphosphate]
Uridine 5'-(trihydrogen pyrophosphate), mono-D-glucosyl ester
Uridine 5'-(trihydrogen diphosphate) alpha-D-gucopyranosyl ester
Uridine 5'-(trihydrogen diphosphate), mono-a-d-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphate), p'-a-D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphate), p'-I+--D-glucopyranosyl ester
Uridine 5'-pyrophosphate, alpha-D-glucopyranosyl ester (6CI,7CI)
Uridine 5'-(trihydrogen diphosphate), mono-I+--D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphate), P'-a-D-glucopyranosyl ester (9CI)
Uridine 5'-(trihydrogen diphosphoric acid), mono-a-D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphoric acid), mono-I+--D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphoric acid), p'-a-D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphoric acid), p'-alpha-D-glucopyranosyl ester
Uridine 5'-(trihydrogen diphosphoric acid), p'-I+--D-glucopyranosyl ester
Uridine 5/'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D- GLUCOPYRANOSYL ESTER
Uridine 5'-(trihydrogen diphosphoric acid), mono-alpha-D-glucopyranosyl ester
Uridine 5'-(trihydrogen pyrophosphate), mono-alpha-D-glucopyranosyl ester (8CI)
[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)