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Uridine triphosphate

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Identification
Molecular formula
C9H15N2O15P3
CAS number
63-39-8
IUPAC name
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
State
State

At room temperature, uridine triphosphate is typically found in a solid crystalline state. As a powder, it is often stored in a desiccated container to prevent degradation due to moisture. It is usually handled with care in laboratory environments to maintain its stability and purity.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
484.14g/mol
Molar mass
484.1410g/mol
Density
2.2000g/cm3
Appearence

Uridine triphosphate (UTP) typically appears as a white to off-white powder. It is hygroscopic, meaning it can absorb moisture from the air. UTP is commonly supplied in its free acid form or as a trisodium salt. In certain lights, it might also exhibit a crystalline appearance due to its solid-state form.

Comment on solubility

Solubility of [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl phosphono hydrogen phosphate

The solubility of this complex compound, C9H15N2O15P3, can be quite intriguing due to its structural features that include multiple functional groups. Here are some key points to consider:

  • Hydrophilicity: Due to the presence of hydroxyl (-OH) and phosphate groups, the compound is likely to exhibit significant hydrophilic character, enhancing its solubility in polar solvents such as water.
  • Solvent Compatibility: While water is a primary solvent, the solubility in organic solvents may vary. Understanding the polarity and hydrogen bonding capabilities of the solvent will be crucial.
  • pH Dependency: The solubility could also vary with changes in pH, especially given the potential for ionization of functional groups in differing pH conditions. This can lead to different forms of the compound being soluble at various levels.

Overall, the solubility characteristics of this compound showcase the interplay of various chemical properties, revealing how structural elements influence its behavior in different environments. Understanding these aspects can be pivotal in applications involving this chemical.

Interesting facts

Interesting Facts About [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate

This complex molecule is intriguing not only for its chemical structure but also for its potential applications in various fields. Here are some fascinating aspects of this compound:

  • Biochemical Relevance: The presence of the pyrimidine structure indicates potential interactions with nucleic acids, making it of great interest in biochemistry and molecular biology.
  • Phosphorylation Role: As a phosphoryl compound, it plays a critical role in biochemical reactions, particularly in energy transfer processes within cells.
  • Drug Design: The multifunctionality of this compound opens doors to drug design, especially in targeting enzymes involved in metabolic pathways.
  • Synthetic Pathways: The synthesis of this compound requires advanced organic chemistry techniques, highlighting the sophistication required to manipulate its molecular architecture.
  • Stability Factors: Given its complex structure, researchers have been studying how environmental factors such as pH and temperature can affect its stability and reactivity.

Potential Applications

Beyond its synthesis and composition, this compound can pave the way for:

  • Developing new pharmaceuticals that can mimic or inhibit natural biochemical pathways.
  • Research in genetic engineering, given its potential interactions with RNA or DNA.
  • Innovations in material science by using its phosphate groups to build new polymer architectures.

As scientist Albert A. Michelson once said, "The greatest advancements are possible when we understand that the universe is composed of intricate structures." This compound represents a tiny yet essential piece of that intricate puzzle, which continues to inspire new discoveries.

Synonyms
uridine 5'-triphosphate
uridine triphosphate
63-39-8
Uteplex
Uridine 5'-(tetrahydrogen triphosphate)
UTP
5'-UTP
Uridine 5'-triphosphoric acid
INS316
uridine-5'-triphosphate
BRN 0071520
H4utp
EINECS 200-558-7
INS-316
UT0S826Z60
UTP;Uridine 5'-triphosphate
CHEMBL336296
Ara-utp
DTXSID0041147
CHEBI:15713
4-24-00-01222 (Beilstein Handbook Reference)
URIDINE TRIPHOSPHATE [WHO-DD]
URIDINE 5'-TRIPHOSPHATE [MI]
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Uridine 5'-triphosphate tris salt
(((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid
Triphosphate, Uridine
uridine5'-triphosphate
INS 316
108321-53-5
araUridine-5'-triphosphate
UNII-UT0S826Z60
uridintriphosphat
UTP Solution
ara UTP
(((((((2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)phosphonic acid
(((2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl) phosphono hydrogen phosphate
({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
3h-uridine triphosphate
Spectrum_001697
Spectrum2_000525
Spectrum3_001596
Spectrum4_000851
Spectrum5_001167
bmse000295
5'UTP
SCHEMBL76682
Uridine 5'triphosphoric acid
BSPBio_003192
KBioGR_001481
KBioSS_002177
DivK1c_000269
SPBio_000509
GTPL1734
uridine 5''-triphosphoric acid
Uridine 5-Triphosphate Solution
DTXCID8021147
KBio1_000269
KBio2_002177
KBio2_004745
KBio2_007313
KBio3_002692
5''-UTP
NINDS_000269
BDBM50118213
AKOS016011172
CS-7777
DB04005
Uridine 5'(tetrahydrogen triphosphate)
IDI1_000269
Uridine mono(tetrahydrogen triphosphate)
Uridine-5'-(tetrahydrogen triphosphate)
NCGC00163323-01
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
266356-22-3
uridine 5''-(tetrahydrogen triphosphate)
CAS 60102-52-5
HY-107372
NS00014367
C00075
F85566
1-beta-D-Arabinofuranosyluridine-5'-triphosphate,
Uridine, mono(tetrahydrogen triphosphate) (ester)
Uridine 5'-(tetrahydrogen triphosphate) (8CI,9CI)
BRD-A89637065-001-01-0
DC99D596-4755-4E87-B3AA-F1D6CFEDCE9A
Q32904692
((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
[[[5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid
2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-.beta.-D-ribofuranosyl]-