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D-sorbitol

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Identification
Molecular formula
C6H14O6
CAS number
50-70-4
IUPAC name
(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
State
State

At room temperature, D-sorbitol is typically found in a solid state as a crystalline powder. However, in a concentrated aqueous solution, it takes the form of a viscous liquid.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.00
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.00
General information
Molecular weight
182.17g/mol
Molar mass
182.1720g/mol
Density
1.4890g/cm3
Appearence

D-sorbitol appears as a white, odorless, crystalline powder or flake-like solid. It is hygroscopic and may also be available in liquid form as a syrup, depending on its concentration in water.

Comment on solubility

Solubility of (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol

(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol, with the chemical formula C6H14O6, exhibits notable solubility characteristics in various solvents. Its structure features multiple hydroxyl (–OH) groups, which significantly enhance its ability to interact with water molecules. Here are key points regarding the compound's solubility:

  • Soluble in Water: The presence of six hydroxyl groups makes this compound highly hydrophilic, allowing it to readily dissolve in water at room temperature.
  • Insoluble in Non-Polar Solvents: Due to its polar nature from the numerous hydroxyl groups, (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol shows poor solubility in non-polar solvents such as hydrocarbons (e.g., hexane, pentane).
  • Salting Effects: Its solubility can be affected by the presence of salts in the solution, as some salts may compete with the solvation of the hexol, potentially reducing its effective concentration in solution.

As a result of its structural characteristics, general observations suggest that this compound is not only soluble in water but also highly versatile in biochemistry, where it may be involved in various biochemical pathways due to its solubility profile. Therefore, understanding its solubility is crucial for applications in chemistry and biology.

Interesting facts

Exploring the World of (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol

(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol, often referred to as a sugar alcohol, is a fascinating compound that plays a significant role in both nature and various applications. Here are some interesting facts that highlight its uniqueness:

  • Natural Occurrence: This compound is found in several plants, contributing to their sweetness while also serving as a carbohydrate reserve.
  • Structural Complexity: Characterized by multiple hydroxyl (–OH) groups, its structure allows for hydrogen bonding, resulting in significant interactions with water and organic solvents.
  • Health Benefits: It is often used as a sugar substitute in food and beverages. Its lower caloric content compared to regular sugars makes it an appealing option for those looking to reduce caloric intake.
  • Biotechnology and Medicine: Research suggests that sugar alcohols may have applications in pharmaceuticals as carriers for drug delivery, enhancing the solubility and stability of certain medications.
  • Safety Profile: It’s generally recognized as safe (GRAS) by many health organizations. However, consumption in excess can lead to gastrointestinal discomfort, a consideration that consumers should keep in mind.

In summary, (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol not only illustrates the versatility of organic compounds but also represents a bridge between nature and human innovation. As a chemistry student or scientist, one can appreciate its diverse roles ranging from sweetener to medicinal excipient, shedding light on the multifaceted applications of sugar alcohols in our lives.

Synonyms
D-Sorbitol
sorbitol
D-Glucitol
50-70-4
glucitol
L-Gulitol
(-)-Sorbitol
Glucarine
D-(-)-Sorbitol
Diakarmon
Sorbilande
Sorbostyl
Esasorb
Multitol
Neosorb
Nivitin
Sorbite
Sorbol
Cholaxine
Sionit
Sionite
Sionon
Siosan
Sorbo
Karion instant
Sorbitol F
Sorbex Rp
Sorbitol FP
D-Sorbol
Sionit K
Sorbex M
Sorbex R
Sorbex S
Sorbex X
Sorbicolan
Sorvilande
Gulitol
D-Sorbite
Neosorb P 60
Foodol D 70
(2R,3R,4R,5S)-Hexane-1,2,3,4,5,6-hexaol
Neosorb 20/60DC
Glucitol, D-
Neosorb 70/70
Neosorb P 20/60
d-Sorbit
Karion
Karion (carbohydrate)
(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
Neosorb 70/02
D-1,2,3,4,5,6-Hexanehexol
FEMA No. 3029
G-ol
CCRIS 1898
Neosorb P 60W
Probilagol
Hexahydric alcohol
iso-sorbide
Glc-ol
AI3-19424
HSDB 801
Sorbitol (e420)
NSC 25944
DTXSID5023588
CHEBI:17924
Sorbitol 3% in plastic container
EINECS 200-061-5
Ins-420(i)
MFCD00004708
UNII-506T60A25R
Sorbitol [USP:NF]
SORBITOL 3.3% IN PLASTIC CONTAINER
1,2,3,4,5,6-Hexanehexol
E 420
E-420(i)
Ins no.420(i)
NSC-25944
506T60A25R
7B5697N
E420
Resulax
Sorbilax
D-Sorbitol, for cell culture
DTXCID903588
Sorbitol (USP)
(2S,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
D-Sorbit 1000 microg/mL in Methanol
Sorbitol (USP:NF)
Medevac
SORBITOL [USP]
SORBITOL (II)
SORBITOL [II]
E-420
SORBITOL (MART.)
SORBITOL [MART.]
SORBITOL (USP-RS)
SORBITOL [USP-RS]
Sorbitur
26566-34-7
SORBITOL (EP MONOGRAPH)
SORBITOL [EP MONOGRAPH]
Sorbit DP
C*PharmSorbidex
Sorbitol;D-Glucitol
Liponic 70-NC
CAS-50-70-4
ISOMALT IMPURITY C (EP IMPURITY)
ISOMALT IMPURITY C [EP IMPURITY]
MALTITOL IMPURITY A (EP IMPURITY)
MALTITOL IMPURITY A [EP IMPURITY]
SMR000112219
LACTITOL MONOHYDRATE IMPURITY E (EP IMPURITY)
LACTITOL MONOHYDRATE IMPURITY E [EP IMPURITY]
Sorbitolum
Meritol
Solbitol
Sorbitab
Sorbogem
Sorbitol Instant
Sorbitol S
Sorbitol FK
Sorbit D-Powder
Sorbit S
Sorbit W-Powder
Sorbit WP
Sorbitol (NF)
Neosorb P60
Kyowa Powder 50M
Sorbogem 712
Sorbitol (Glucitol)
Liponic 76-NC
Sorbit D 70
Sorbit DP 50
Sorbit L 70
Sorbit T 70
Sorbit W 70
D-Sorbitol, 99%
Sorbit W-Powder 50
D-Sorbitol (Standard)
D-sorbitol; D-glucitol
D-Sorbitol (JP18)
SORBITOL [HSDB]
SORBITOL [FCC]
SORBITOL [MI]
SORBITOL [VANDF]
D-Sorbitol, >=98%
D-SORBITOL [JAN]
SCHEMBL763
Sorbit Kyowa Powder 50M
bmse000115
bmse000803
bmse001007
D-SORBITOL [FHFI]
Epitope ID:114708
SORBITOL [WHO-DD]
Isomalt impurity, sorbitol-
D-Sorbitol, NF/FCC grade
CHEMBL1682
MLS001333209
MLS001333210
SORBITOL [ORANGE BOOK]
D-Sorbitol, analytical standard
D-Sorbitol, for electrophoresis
CHEBI:30911
D-Sorbitol, BioXtra, >=98%
HY-B0400B
HY-B0400E
HY-B0400R
D-Sorbitol, M400 (Excipient)
MSK3102
D-Sorbitol, for synthesis, 99%
HMS2094K21
HMS2270A18
Pharmakon1600-01300028
HY-B0400
Tox21_201937
Tox21_303388
D-Sorbitol, >=98%, FCC, FG
NSC759608
s2393
AKOS015899604
D-Sorbitol, plant cell culture tested
CCG-229392
DB01638
MS00451
NSC-759608
Sorbitol 3% in plastic container (TN)
NCGC00164353-01
NCGC00164353-02
NCGC00164353-03
NCGC00257447-01
NCGC00259486-01
AC-13186
CS-13177
D-Sorbitol, SAJ first grade, >=97.0%
SBI-0206688.P002
SORBITOL-MANNITOL COMPONENT SORBITOL
D-Sorbitol, for molecular biology, >=98%
CS-1046513
D-Sorbitol, BioUltra, >=99.5% (HPLC)
D-Sorbitol, SAJ special grade, >=99.0%
D-Sorbitol, Vetec(TM) reagent grade, 97%
NS00121242
S0065
SW220289-1
D-Sorbitol, crystallized, >=99.0% (HPLC)
C00794
D00096
E70384
AB00919085_06
D-Sorbitol, liquid, tested according to Ph.Eur.
EN300-7832133
ISOMALT IMPURITY, SORBITOL- [USP IMPURITY]
ISOMALT IMPURITY, SORBITOL-(USP IMPURITY)
Q245280
BRD-K66035042-001-10-1
BRD-K66035042-001-11-9
rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
Sorbitol, European Pharmacopoeia (EP) Reference Standard
75DE42C3-7C3B-4802-95E0-463F02268BDC
Sorbitol, United States Pharmacopeia (USP) Reference Standard
D-Sorbitol, BioReagent, cell culture tested, plant cell culture tested
Sorbitol, Pharmaceutical Secondary Standard; Certified Reference Material
200-061-5
619-324-4