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2,6-Dichloro-4-(imidazolidin-2-ylamino)aniline

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Identification
Molecular formula
C9H11Cl2N3
CAS number
50293-53-5
IUPAC name
2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
State
State

At room temperature, 2,6-Dichloro-4-(imidazolidin-2-ylamino)aniline is typically found as a solid, specifically as crystalline or powder form. This state facilitates its handling and use in various industrial and chemical applications.

Melting point (Celsius)
233.50
Melting point (Kelvin)
506.65
Boiling point (Celsius)
395.40
Boiling point (Kelvin)
668.55
General information
Molecular weight
258.11g/mol
Molar mass
258.1230g/mol
Density
1.4750g/cm3
Appearence

2,6-Dichloro-4-(imidazolidin-2-ylamino)aniline typically appears as off-white to light brown crystals or powder. It is an aromatic diamine with chlorine substitutions, which can sometimes impart a pale coloration due to its chlorinated aromatic ring.

Comment on solubility

Solubility of 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine

The solubility of 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine, with a chemical formula of C9H11Cl2N3, is influenced by its unique structural characteristics. This compound exhibits certain solubility behavior that can be summarized as follows:

  • Polarity: Due to the presence of Cl atoms and amine groups, the compound's polarity can lead to varying solubility in different solvents.
  • Water Solubility: Generally, amines can increase solubility in water; however, the overall solubility in water for this specific compound might be limited.
  • Organic Solvents: It is often more soluble in organic solvents such as ethanol and methanol than in polar solvents like water.
  • pH Influence: The solubility can also be affected by pH levels, as protonation of amine groups in acidic conditions could enhance solubility.

In terms of practical usage and application, it’s essential to conduct further empirical tests to determine the solvent in which this compound is most effectively soluble. As with many chemical compounds, precise solubility data can greatly benefit synthesis and formulation processes.

Interesting facts

Interesting Facts about 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine

This chemical compound, known for its complex structure, has a variety of interesting implications and applications in the field of chemistry and medicine.

Key Features:

  • Dichlorination: The presence of two chlorine atoms enhances the compound's reactivity, making it a useful intermediate in organic synthesis.
  • Imidazole Moiety: The inclusion of a dihydroimidazole ring contributes to biological activities, often exhibiting properties important in pharmaceuticals.
  • Medicinal Properties: Compounds with a similar structure have been studied for their potential as anti-cancer agents and for various other therapeutic uses.

This compound is of particular interest in the development of novel drugs due to its ability to interact with various biological targets. For instance, the imidazole part of the structure is crucial in mimicking active sites of enzymes, potentially leading to applications in enzyme inhibition.

Potential Applications:

  • As a precursor in the synthesis of more complex pharmaceuticals.
  • In material science, for developing new polymers or coatings.
  • In biological research, as a tool for studying cellular processes.

Moreover, the exploration of the compound can lead to new findings in both synthetic chemistry and medicinal chemistry, highlighting the importance of interdisciplinary research in enhancing our understanding of chemical compounds and their properties.

In summary, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine not only showcases the fascinating interplay of chemistry and biology, but it also opens opportunities for **innovative research** and applications that could lead to significant advancements in scientific studies.

Synonyms
apraclonidine
66711-21-5
4-Aminoclonidine
Apraclonidina
Aplonidine
Apraclonidinum
p-aminoclonidine
Apraclonidinum [INN-Latin]
Apraclonidina [INN-Spanish]
2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
UNII-843CEN85DI
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
843CEN85DI
CHEBI:2788
Apraclonidine (INN)
Iopidine (TN)
CHEMBL647
DTXSID1048415
para-aminoclonidine
1,4-Benzenediamine, 2,6-dichloro-N'-(4,5-dihydro-1H-imidazol-2-yl)-
2,6-dichloro-N(1)-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
APRACLONIDINE [INN]
Apraclonidinum (INN-Latin)
Apraclonidina (INN-Spanish)
Apraclonidine [INN:BAN]
Apraclonidine; Lopidine; NC 14; p-Aminoclonidine
2-(4-amino-2,6-dichloro)phenyliminoimidazolidine
p-amino clonidine
Aminoclonidine, p
para-amino clonidine
starbld0003083
Lopac-A-0779
APRACLONIDINE [MI]
Lopac0_000033
SCHEMBL34127
APRACLONIDINE [VANDF]
APRACLONIDINE [WHO-DD]
GTPL7117
DTXCID9028388
BDBM81926
S01EA03
BDBM50021812
NSC_51763
PDSP1_000790
PDSP2_000778
AKOS025401361
CCG-204129
DB00964
SDCCGSBI-0050022.P002
SMP1_000016
NCGC00015033-01
NCGC00015033-02
NCGC00015033-03
NCGC00015033-04
NCGC00162050-01
AC-12697
HY-12720
CAS_66711-21-5
DB-054956
CS-0012296
NS00005311
C07668
D07461
EN300-320403
2-(4-amino-2,6-dichlorophenylimino)imidazolidine
L000686
L013394
2-(4-Amino-2,6-dichlorophenylamino)-2-imidazoline
2-(4-amino-2,6-dichlorophenylimino) imidazolidine
Q4781812
BRD-K38911213-003-01-6
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine
1,4-Benzenediamine, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-
2,6-DICHLORO-N1-(IMIDAZOLIDIN-2-YLIDENE)BENZENE-1,4-DIAMINE
P-AMINOCLONIDINE2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine (p-aminoclonidine)
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine(p-Aminoclonidine)