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Bromothymol blue

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Identification
Molecular formula
C27H28Br2O5
CAS number
76-59-5
IUPAC name
2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol
State
State

At room temperature, bromothymol blue is typically found in a solid powder form. However, when used in laboratory settings, it is often dissolved in a solution where it serves as a pH indicator.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
736.40
Boiling point (Kelvin)
1 009.50
General information
Molecular weight
624.39g/mol
Molar mass
624.3850g/mol
Density
1.2693g/cm3
Appearence

Bromothymol blue appears as a brownish-green to dusty purple solid. It is commonly used as a pH indicator. In its solution form, it tends to impart a yellow color under acidic conditions and a blue color under basic conditions. The transition range typically appears green due to the mixture of acidic and basic forms of the dye.

Comment on solubility

Solubility of 2,6-Dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol

When examining the solubility of the compound 2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol, several factors come into play:

  • Polarity: The presence of multiple bromine atoms and a phenolic hydroxyl group can affect the compound's overall polarity. Generally, increased polarity enhances solubility in polar solvents.
  • Hydrophobic interactions: The large hydrophobic regions due to the aromatic rings may limit solubility in water but promote solubility in organic solvents.
  • Functional groups: The hydroxyl group (-OH) can engage in hydrogen bonding, potentially aiding solubility in polar solvents like water.

However, it's crucial to note that 2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol may exhibit limited solubility in water compared to organic solvents due to its complex hydrophobic character.

In summary, while solubility depends on various interactions, the intricate balance between hydrophilic and hydrophobic properties ultimately dictates the behavior of this compound in different environments.

Interesting facts

Interesting Facts about 2,6-Dibromo-4-[1-(3,5-Dibromo-4-Hydroxy-Phenyl)-1-Methyl-Ethyl]Phenol

This intriguing compound is often involved in discussions about environmental science and toxicology due to its unique structure and properties. Here are some fascinating aspects of 2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol:

  • Structural Complexity: The compound features a complex arrangement of bromine and hydroxyl functional groups, which can influence its chemical behavior and interactions.
  • Potential Applications: Due to its structural characteristics, it is of interest in fields like medicinal chemistry and materials science, where understanding the effects of halogen substituents can lead to the development of new therapeutic agents or advanced materials.
  • Environmental Impact: Compounds containing bromine are studied for their potential effects on the environment, including their persistence and bioaccumulation in ecosystems, raising concerns regarding their ecological footprint.
  • Research Significance: The compound may be a subject of research to explore its biological activities, including anti-inflammatory and antimicrobial properties, making it a potential candidate for drug development.
  • Analogous Compounds: This compound belongs to a class of polybrominated phenols, which are known for their diverse chemical behaviors and effects on living organisms, further emphasizing the need for thorough toxicity assessments.

Overall, the study of 2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol presents a rich tapestry of scientific inquiry, emphasizing the importance of understanding complex chemical compounds in both environmental and health contexts. As one researcher aptly put it, *"In the world of chemistry, the smallest changes in composition can yield profoundly different properties."*

Synonyms
Tetrabromobisphenol A
79-94-7
3,3',5,5'-Tetrabromobisphenol A
4,4'-(propane-2,2-diyl)bis(2,6-dibromophenol)
Bromdian
2,2-Bis(3,5-dibromo-4-hydroxyphenyl)propane
4,4'-Isopropylidenebis(2,6-dibromophenol)
TBBPA
Firemaster BP 4A
Tetrabromodian
Fire Guard 2000
Great Lakes BA-59P
2,6-dibromo-4-[2-(3,5-dibromo-4-hydroxyphenyl)propan-2-yl]phenol
Saytex RB 100PC
Tetrabromodiphenylopropane
Firemaster BP4A
2,2',6,6'-TETRABROMOBISPHENOL A
FG 2000
Phenol, 4,4'-(1-methylethylidene)bis[2,6-dibromo-
4,4'-(1-Methylethylidene)bis(2,6-dibromophenol)
BA 59
3,5,3',5'-Tetrabromobisphenol A
NSC 59775
4,4'-propane-2,2-diylbis(2,6-dibromophenol)
33'55'-Tetrabromobisphenol A
DTXSID1026081
Saytex RB-100
4,4'-Isopropylylidenebis(2,6-dibromophenol)
2,2-Bis(4-hydroxy-3,5-dibromophenyl)propane
MFCD00013962
FQI02RFC3A
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol
CHEMBL184450
CHEBI:33217
Phenol, 4,4'-isopropylidenebis(2,6-dibromo-
Phenol, 4,4'-isopropylidenebis[2,6-dibromo-
4,4'-(2,2-propanediyl) bis[2,6-dibromo]phenol
NSC-59775
Phenol, 4,4'-(1-methylethylidene)bis(2,6-dibromo-
FR-1524
Tetrabromobisphenol A 50 microg/mL in Methanol
DTXCID406081
CAS-79-94-7
CCRIS 6274
Tetrabromo bisphenol A
HSDB 5232
4,4'-(1-methylethylidene)bis[2,6-dibromophenol]
EINECS 201-236-9
UNII-FQI02RFC3A
3,3',5,5'-Tetrabromo bisphenol A
FLAME CUT 120G
4,4'-(2,2-PROPANEDIYL)BIS(2,6-DIBROMOPHENOL)
3osw
XDI
4,6-dibromophenol)
2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxyphenyl)-1-methylethyl]phenol
TBBA/TBBPA
TBBP-A
Saytex RB-100 ABS
2,5-dibromophenyl)propane
TETRABROMO-4,4'-ISOPROPYLIDENEDIPHENOL
bmse000567
Tetrabromobisphenol ''A''
EC 201-236-9
2,2,6,6-Tetrabromo-4,4-Isopropylidene Phenol
4,4'-(1-Methylethylidene)bis(2,6-dibromophenol)2,2-bis(3,5-dibromo-4-hydroxyphenyl)propane
Oprea1_822733
SCHEMBL18647
MLS002152878
BIDD:ER0631
330396_ALDRICH
2,6,6'-Tetrabromobisphenol A
3,3',5'-Tetrabromobisphenol A
3,3,5,5-Tetrabromobisphenol A
BP_15
GLXC-20216
TETRABROMOBISPHENOL A [MI]
ALBB-031649
NSC59775
TETRABROMOBISPHENOL A [IARC]
Tox21_201182
Tox21_201981
Tox21_300561
2,5-dibromo-4-hydroxyphenyl)propane
BDBM50150793
BR1202
c0763
STK048486
ZINC01689786
2,2',6,6'-Tetrabromo bisphenol A
2,6-dibromo-4-[1-(3,5-dibromo-4-hydroxy-phenyl)-1-methyl-ethyl]phenol
AKOS000491577
2,2'',6,6''-Tetrabromobisphenol A
3,3'',5,5''-tetrabromobisphenol A
3,3\',5,5\'-tetrabromobisphenol A
CP-2000
CS-W013812
NCGC00091463-01
NCGC00091463-02
NCGC00091463-03
NCGC00091463-04
NCGC00091463-05
NCGC00091463-06
NCGC00254356-01
NCGC00258734-01
NCGC00259530-01
AC-11719
AS-12834
SMR001224492
Phenol,4'-isopropylidenebis[2,6-dibromo-
3,3',5,5'-Tetrabromobisphenol A, 97%
phenol, 4,4'-isopropylidenebis (dibromo-)
2,2-bis(3,5dibromo-4-hydroxyphenyl)propane
4,4''-Isopropylidenebis(2,6-dibromophenol)
4,4'-isopropylidene-bis(2,6-dibromophenol)
NS00002438
T0032
EN300-64638
TETRABROMOBISPHENOL A, 3,3',5,5'-
2,2-bis(3,5-dibromo-4-hydroxyphenyl)-propane
2,2-bis-(3,5-dibromo-4-hydroxyphenyl)propane
S12384
2,2-bis-(3,5-dibromo-4-hydroxyphenyl)-propane
2,2',6,6'-TETRABROMOBISPHENOL A [HSDB]
Phenol,4'-(1-methylethylidene)bis[2,6-dibromo-
Q425246
SR-01000596914
Tetrabromodian: tetrabromodihydroxy diphenylpropane
4,4''-(1-Methylethylidene)bis(2,6-dibromophenol)
4,4''-(2,2-propanediyl) bis[2,6-dibromo]phenol
4,4''-(propane-2,2-diyl)bis(2,6-dibromophenol)
SR-01000596914-1
2,2',6,6'-Tetrabromo-4,4'-isopropylidene bisphenol
2,2-bis-(4'-hydroxy-3',5'-dibromophenyl)-propane
3,3',5,5'-Tetrabromobisphenol A, analytical standard
3,3',5,5'-Tetrabromo-4,4-dihydroxy-2,2-diphenylpropane
3,3',5,5'-Tetrabromo-4,4'-dihydroxy-diphenyl-dimethyl-methane
3,3',5,5'-Tetrabromobisphenol A, certified reference material, TraceCERT(R)
201-236-9
InChI=1/C15H12Br4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H