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Staurosporine

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Identification
Molecular formula
C28H26N4O3
CAS number
62996-74-1
IUPAC name
(2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate
State
State

At room temperature, staurosporine is a solid.

Melting point (Celsius)
256.15
Melting point (Kelvin)
529.30
Boiling point (Celsius)
476.85
Boiling point (Kelvin)
750.00
General information
Molecular weight
466.54g/mol
Molar mass
466.5350g/mol
Density
1.3800g/cm3
Appearence

Staurosporine is typically found as a pale yellow to off-white crystalline solid.

Comment on solubility

Solubility of (2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate

The solubility of the compound with the formula C28H26N4O3 can vary significantly depending on several factors, including the solvent used, temperature, and pH. Here are some key points regarding its solubility:

  • Solvent Type: Generally, organic compounds such as this one may exhibit better solubility in polar organic solvents like dimethyl sulfoxide (DMSO) or methanol, compared to non-polar solvents.
  • Temperature Influence: An increase in temperature often enhances solubility. Therefore, warming the solvent may improve the compound's dissolution rate.
  • pH Effects: The solubility of amine-containing compounds can be affected by the pH of the solution. Acidic conditions might protonate the amine groups, potentially increasing solubility in aqueous solutions.

Key Characteristics: - **Slow Dissolution:** The compound may have a slow dissolution rate due to its complex structure. - **Potential Insolubility:** In non-polar solvents like hexane, solubility may be very limited.

In conclusion, while the solubility of (2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate can be influenced by various external factors, further empirical studies are necessary to determine its precise solubility profile in different media.

Interesting facts

Interesting Facts about (2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate

This fascinating compound is not only notable for its complex structure but also for its potential applications in various fields of chemistry and medicine. Here are some intriguing aspects:

  • Structure Complexity: The compound features a pyrrolo[1,2-a]indole framework, which is known for its contributions to diverse biological activities.
  • Potential Pharmaceutical Applications: Compounds of this type have shown promise in medicinal chemistry, particularly in the development of anti-cancer agents. Their unique structural features often play a role in interacting with biological macromolecules.
  • Biological Significance: The presence of multiple amino groups indicates potential for biological reactivity. This can make compounds of this sort useful as probes or in therapeutic developments targeting various diseases.
  • Environmental Impact: Research into chemicals such as this one can also contribute to our understanding of how complex organic compounds behave in biological systems and their environmental implications.
  • Synthesis Challenges: The intricate synthesis process of such compounds can involve multiple steps, leading chemists to explore innovative reaction pathways and methodologies.

In summary, the compound (2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate stands out for its impressive structural sophistication and the promising avenues it opens in scientific research. As chemists explore the functionalities of such compounds, they not only advance our understanding of chemistry but also contribute to future medical breakthroughs.

Synonyms
2,7-Diaminomitosene
78598-43-3
(2,6-diamino-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-4-yl)methyl carbamate
1H-Pyrrolo(1,2-a)indole-5,8-dione, 2,7-diamino-9-(((aminocarbonyl)oxy)methyl)-2,3-dihydro-6-methyl-
CHEMBL85852
DTXSID50999874
(2,7-Diamino-6-methyl-5,8-dioxo-2,3,5,8-tetrahydro-1H-pyrrolo[1,2-a]indol-9-yl)methyl hydrogen carbonimidate