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Tocopherol

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Identification
Molecular formula
C29H50O2
CAS number
10191-41-0
IUPAC name
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol
State
State

At room temperature, tocopherol is a thick, oily liquid. It is not a crystalline solid, which is one of the features that distinguish it from many other vitamins.

Melting point (Celsius)
2.50
Melting point (Kelvin)
275.65
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.00
General information
Molecular weight
430.72g/mol
Molar mass
430.7170g/mol
Density
0.9508g/cm3
Appearence

Tocopherol, commonly known as vitamin E, typically appears as a pale yellow to amber, viscous liquid. Depending on its isoform and purity, it can appear clear and free from particulates or turbidity.

Comment on solubility

Solubility of 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol (C29H50O2)

The solubility of 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol, a complex organic compound, is influenced by its unique chemical structure. Generally, larger organic molecules exhibit the following trends in solubility:

  • Polar vs. Nonpolar: This compound has a significant hydrophobic tail, which suggests that it is more likely to be soluble in nonpolar solvents.
  • Solvent Compatibility: It is likely to dissolve well in organic solvents such as hexane or chloroform, while showing limited solubility in polar solvents like water.
  • Molecular Weight: The relatively high molecular weight can impede solubility in common solvents, making it less soluble compared to smaller compounds.

As a general rule, the “like dissolves like” principle applies here: nonpolar compounds tend to dissolve in nonpolar solvents, while polar compounds are more soluble in polar solvents. Thus, for C29H50O2, a greater solubility is anticipated in organic media rather than in aqueous solutions.

In summary, while the solubility of this compound may present challenges in aqueous environments, its stability and compatibility in organic solvents emphasize its importance in various applications.

Interesting facts

Interesting Facts about 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol

2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol, commonly known as a form of Vitamin E, is a fascinating compound with a range of significant biological properties. Here are some intriguing aspects of this compound:

  • Antioxidant Properties: This compound exhibits powerful antioxidant properties, which means it helps in neutralizing free radicals in the body. This is vital for protecting cells from oxidative damage.
  • Health Benefits: Studies suggest that it may play a role in supporting cardiovascular health, enhancing immune function, and reducing the risk of chronic diseases.
  • Chemical Structure: The unique structure of this compound allows it to easily integrate into cellular membranes, where it exerts its beneficial effects.
  • Natural Sources: It is found naturally in various foods, particularly in nuts, seeds, and green leafy vegetables, making it a vital component of a healthy diet.

Moreover, its relevance extends beyond nutrition. According to researchers, "The incorporation of this compound in skincare formulations can provide significant skin protection against environmental stressors." As a result, it is often included in cosmetics and skincare products for its protective benefits.

As we continue to study 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol, its potential applications in health and wellness could broaden further, making it a compound of great interest for scientists and consumers alike.

Synonyms
DL-ALPHA-TOCOPHEROL
10191-41-0
alpha-tochopherol
dl-|A-tocopherol
TOCOPHEROL
Ephanyl
Tocopheroxy radical
alpha-Tocopherol, DL-
DL-alpha tocopherol
Vitamin E DL-alpha
dl-.alpha.-Tocopherol
all-rac-alpha-Tocopherol
a-Tocopherol
UNII-7QWA1RIO01
DL-5,7,8-trimethyltocol
113085-06-6
7QWA1RIO01
Vita E
CCRIS 5853
1406-18-4
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
EINECS 233-466-0
.Alpha.-tocopherol, DL-
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol
RONOTEC DF 120
IRGANOX E 210
UVINUL 2000AO
BRN 0094012
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
CHEMBL49563
INS NO.307C
RAC-.ALPHA.-TOCOPHEROL
INS-307C
dl-?-Tocopherol
HSDB 8261
DL-alpha-Tocopherol (Vitamin E)
EC 233-466-0
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
.alpha.-Tocopherol
5-17-04-00168 (Beilstein Handbook Reference)
DL-.ALPHA.-TOCOPHEROL [MI]
E-307C
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
all-rac-alpha-Tocopherol (Vitamin E)
(2S, 4'R, 8'S)-alpha-Tocopherol
(2S, 4'S, 8'S)-alpha-Tocopherol
J24.789H
(+/-)-alpha-Tocopherol
(2R)-alpha-Tocopherol (Mixture of Diastereomers)
Evitaminum
Waynecomycin
Almefrol
Emipherol
Etamican
Vitayonon
Ilitia
Vitaplex E
Spavit E
ido-E
DL-alpha-Tocopherol (Vitamin E) 10 microg/mL in Acetonitrile
Endo E
Antisterility vitamin
RRR-alpha-tocopherol
(2R, 4'S, 8'R)-alpha-Tocopherol
(2R, 4'S, 8'S)-alpha-Tocopherol
(2S, 4'S, 8'R)-alpha-Tocopherol
d-.alpha.-Tocopherol
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol
Tocopheroxyl radical
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
(+-)-alpha-Tocopherol
SR-05000001813
1411583-24-8
5,6 Trans-Calcipotriol
DTXSID8021355
DL-Tocopherol
NSC-20812
DLalphaTocopherol
.alpha.-Tokoferol
.alpha. Tocopherol
allracalphaTocopherol
alphaTocopherol, DL
rac-alpha-tocopherol
5,8-Trimethyltocol
DLallracalphaTocopherol
Tocopherol (JP17)
(2R)-?-Tocopherol
(2S)-?-Tocopherol
Spectrum_001195
DL- alpha -Tocopherol
DL-all-rac-A-Tocopherol
Spectrum2_000722
Spectrum3_001338
Spectrum4_001771
Spectrum5_000381
TOCOPHEROL, DL-ALPHA
SCHEMBL22303
BSPBio_003095
KBioGR_002282
KBioSS_001675
SPECTRUM310039
(all-R)-.alpha.-Tocopherol
DivK1c_000533
SPBio_000644
alpha-Tocopherol, >=95.5%
DL-alpha-Tocopherol (Standard)
SCHEMBL14315133
(.+-.)-Med-E
(.+/-.)-.alpha.-Tocopherol
CHEBI:93909
HMS501K15
KBio1_000533
KBio2_001675
KBio2_004243
KBio2_006811
KBio3_002315
(2R,8'R)-.alpha.-Tocopherol
MSK1509
NINDS_000533
HMS1923I03
HMS2091C11
Pharmakon1600-00310039
ALPHA-TOCOPHEROL, DL-(II)
C29H50O2 (DL-alpha-tocopherol)
DL-ALPHA-TOCOPHEROL(307C)
EDA43482
EDA43483
HY-W020044R
LGC58324
NSC20812
NSC82623
TOCOPHEROL,DL-ALPHA [VANDF]
VKB51838
DL-ALPHA TOCOPHEROL [MART.]
BBL027614
BDBM50436220
CCG-40162
MFCD00072051
NSC-82623
NSC755839
s6104
STL372809
DL-ALPHA TOCOPHEROL [WHO-DD]
(2S, 4'R, 8'S)-?-Tocopherol
(2S, 4'S, 8'R)-?-Tocopherol
.ALPHA.-TOCOPHEROL, DL-[II]
AKOS015960364
1ST1509
ALL-RAC-ALPHA-TOCOPHEROL [FCC]
DB14476
HY-W020044
NSC-755839
SDCCGMLS-0066634.P001
.ALPHA.-TOCOPHEROL, DL- [II]
IDI1_000533
NCGC00095254-01
NCGC00095254-02
NCGC00095254-03
NCGC00095254-05
NCGC00095254-06
AC-10544
MSK1509-1000
SY012869
SY057064
VS-08569
SBI-0051261.P003
(+/-)-alpha-Tocopherol, analytical standard
CS-0031997
NS00005562
T0251
EN300-20897
1ST1509-1000
D02332
D70247
AB00051898_02
SR-05000001813-1
SR-05000001813-2
(+/-)-alpha-Tocopherol, synthetic, >=96% (HPLC)
(+/-)-alpha-Tocopherol, tested according to Ph.Eur.
BRD-A82892199-001-01-7
BRD-A82892199-001-04-1
Q27165663
(+/-)-?-Tocopherol Solution in Methanol, 1000?g/mL
(+/-)-alpha-Tocopherol, SAJ special grade, >=96.0%
F0001-2420
(+/-)-alpha-Tocopherol Solution in Methanol, 1000mug/mL
6Chromanol, 2,5,7,8tetramethyl2(4,8,12trimethyltridecyl)
7A4513C3-131C-41D4-B6A0-7ED994AC2947
all-rac-alpha-TOCOPHERYL ACETATE IMPURITY C [EP IMPURITY]
alpha-Tocopherol, British Pharmacopoeia (BP) Reference Standard
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol #
alpha-Tocopherol, European Pharmacopoeia (EP) Reference Standard
3,4Dihydro2,5,7,8tetramethyl2(4,8,12trimethyltridecyl)2Hbenzopyran6ol
Alpha Tocopherol, United States Pharmacopeia (USP) Reference Standard
Alpha Tocopherol, Pharmaceutical Secondary Standard; Certified Reference Material
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, radical ion(1+), (2R-(2R*(4R*,8R*)))-
2H-1-Benzopyran-6-ol,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R*(4R*,8R*)]-(.+-.)-
2H-1-Benzopyran-6-ol,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R-[2R*(4R*,8R*)]]-