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Allantoin

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Identification
Molecular formula
C4H6N4O3
CAS number
97-59-6
IUPAC name
(2,5-dioxoimidazolidin-4-yl)urea
State
State

At room temperature, allantoin is a solid. It is stable under normal conditions and is often utilized in both solid and solution form for various applications.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
158.12g/mol
Molar mass
158.1190g/mol
Density
1.4500g/cm3
Appearence

Allantoin appears as a white, odorless crystalline powder. It is known for being non-toxic, non-allergenic, and safe for topical use in cosmetic and dermatological applications.

Comment on solubility

Solubility of (2,5-dioxoimidazolidin-4-yl)urea

The solubility of (2,5-dioxoimidazolidin-4-yl)urea, with the chemical formula C4H6N4O3, can be quite interesting to examine. This compound exhibits the following characteristics regarding its solubility:

  • Polarity: Given the presence of multiple functional groups such as urea and carbonyls, (2,5-dioxoimidazolidin-4-yl)urea is likely to possess a level of polarity, affecting its solubility in various solvents.
  • Solvent Compatibility: This compound is typically soluble in polar solvents such as water and alcohols due to its ability to form hydrogen bonds.
  • Temperature Dependency: The solubility may increase with temperature, which is common for many organic compounds. Thus, heating a solution may promote better dissolution.

In summary, the solubility of (2,5-dioxoimidazolidin-4-yl)urea is significantly influenced by its molecular structure and the nature of the solvent used. Its compatibility with polar solvents allows it to dissolve effectively, showcasing its potential utility in various chemical applications.

Interesting facts

Interesting Facts about (2,5-Dioxoimidazolidin-4-yl)urea

(2,5-Dioxoimidazolidin-4-yl)urea, a compound of significant interest within the realm of organic chemistry, has garnered attention due to its unique structural attributes and potential applications. Here are some engaging aspects to consider:

  • Structural Highlight: This compound contains a five-membered ring structure combining both oxygen and nitrogen atoms, which is characteristic of imidazolidin derivatives. The presence of both carbonyl groups and urea functionality contributes to its intriguing reactivity.
  • Biological Significance: Compounds with similar structures have been studied for their biological activities. This compound may exhibit properties that could make it relevant in medicinal chemistry, particularly for the development of new pharmaceuticals.
  • Chemical Versatility: Due to its functional groups, (2,5-Dioxoimidazolidin-4-yl)urea shows promise in various chemical reactions. It can serve as a building block for synthesizing more complex molecules, facilitating innovation in organic synthesis.
  • Research Potential: Recent studies suggest that this compound and its derivatives could be examined for anti-inflammatory or anti-cancer properties, making it a candidate for future drug development initiatives.
  • Educational Value: For chemistry students, working with such a compound offers insights into nitrogen-containing heterocycles and their importance in both organic synthesis and pharmaceutical applications.

As we continue to explore the complexities of compounds like (2,5-Dioxoimidazolidin-4-yl)urea, one can only ponder the vast possibilities they hold for future research and applications in science.

Synonyms
allantoin
97-59-6
5-Ureidohydantoin
Glyoxyldiureide
1-(2,5-dioxoimidazolidin-4-yl)urea
Cordianine
Glyoxyldiureid
Allantol
Alantan
Sebical
AVC/Dienestrolcream
Urea, (2,5-dioxo-4-imidazolidinyl)-
Psoralon
Septalan
Hydantoin, 5-ureido-
Cutemol emollient
(2,5-Dioxo-4-imidazolidinyl)urea
Uniderm A
(2,5-dioxoimidazolidin-4-yl)urea
Glyoxylic(acid) diureide
DL-Allantoin
Glyoxylic diureide
NSC 7606
5-Ureido-2,4-imidazolidindion
Alwextin
Caswell No. 024
CCRIS 1958
2,5-Dioxo-4-imidazolidinyl-urea
N-(2,5-Dioxo-4-imidazolidinyl)urea
EPA Pesticide Chemical Code 085701
4-ureido-2,5-Imidazolidinedione
Idelalisib metabolite m1a
AI3-15281
NSC-7606
Fancol TOIN
5-Ureidohydrantoin
EINECS 202-592-8
MFCD00005260
BRN 0102364
(+/-)-Allantoin
5-Ureido-2,4-imidazolidindione
DTXSID3020043
UNII-344S277G0Z
CHEBI:15676
HSDB 7490
NSC7606
Allantoin (JAN/USP)
N-(2,5-dioxoimidazolidin-4-yl)urea
344S277G0Z
97-59-6 (racemic)
DTXCID0043
MLS000737882
5377-33-3
Sd 101
Allantoin [USAN:USP:BAN:JAN]
EC 202-592-8
5-25-15-00338 (Beilstein Handbook Reference)
DL-ALLANTOIN-5-13C; 1-15N
urea, N-(2,5-dioxo-4-imidazolidinyl)-
ALLANTOIN (II)
ALLANTOIN [II]
Herpecin L
ALLANTOIN (MART.)
ALLANTOIN [MART.]
D00121
ALLANTOIN (USP-RS)
ALLANTOIN [USP-RS]
ALLANTOIN (EP MONOGRAPH)
ALLANTOIN [EP MONOGRAPH]
ALLANTOIN (USP MONOGRAPH)
ALLANTOIN [USP MONOGRAPH]
Allantoin (USAN:USP:BAN:JAN)
C4H6N4O3
Allantoin [USAN:BAN]
SMR000528073
SR-01000766252
Alantoina
Scarderm
Teevodar
Purple
ScarEquate
Allantoin Cream
Mulberry Serum
Mulberry Toner
Chamois Glide
Scar Reducer
Sol Mouthwash
HealingCVS
Cool Melon
Equate Scar
Kenaf wet wipe
Polyactil N
Scar Cream
Scar Care
Anti Chafe Balm
Meijer Scar Gel
Mulberry Emulsion
Scar Gel
Bruise MD
Mederma for Kids
ScarCVS
Rite Aid Scar
Vitamin C Liquid
BL Vital Serum
AC Control Serum
BL Vital
BL Vital Essence
BL Vital Skin
CAS-97-59-6
Equate ScarTopical
Advanced Scar Gel
Bodyglide For Her
Prestwick_11
NCGC00016358-01
Allation,(S)
DCH Scar
Diabetic Wound Gel
QC Scar
Run Guard Original
U-max Multi BB
5-ureido-Hydantoin
Allantoin (8CI)
Allantoin .4%
Burn-B Gone OTC
GMDANSU Skin
Run Guard Sensitive
Kenaf wet wipe kids
Allantoin 0.5%
Allantoin-0.5%
Advanced Derma Spray
ARC Skin Protectant
ATOBOS
HAHALADY
NAAMAN
Sarene Soothing Skin
Seaweed Aqua Massage
SEUK
Smart Brushing Tooth
The Prestige Essence
Ultra Soothing Toner
VASHTI
Healing Head to Toe
Allantoin (Standard)
GMDANSU Eye Serum
Pelo Baum Brow Brow
Pelo Baum Lash Lash
Mederma Advanced Scar
Mandelic 2 Peel Gel
RAPHAGENPOWDE R
SOOSUL ESSENCE
ALRA THERAPY
ATOBOS WASH
MIRACLE GYN
Advanced Derma Therapy
Wound Gel Professional
FUCOIDAN ESSENCE
Lycoris rubus whitening
NoblRose Foam Cleanser
Version X Scalp Tonic
DOG MX BANDAGE
First honey Burn Salve
NEWSTEM Rx Intensive
Spectrum_001078
REVAGAIN Scalp Tonic
FUCOIDAN SKINCURE
ALLANTOIN [JAN]
ALLANTOIN [MI]
Jilgyungyi (6 Tablets)
PORE CARE Lotus Mask
Scar GelAdvanced Formula
ALLANTOIN [HSDB]
ALLANTOIN [USAN]
Bodyglide anti chafe balm
Prestwick0_000002
Prestwick1_000002
Prestwick2_000002
Prestwick3_000002
Spectrum2_000219
Spectrum3_000876
Spectrum4_000716
Spectrum5_001526
Target Advanced Scar Gel
ALLANTOIN [VANDF]
Nano Gold Bio Mask Pack
Baby Wipes with Allantoin
Drs. pharmacy Scar Cream
SBS 41 Medicated Cream
ECO FACE 9
Jilgyungyi (10 Tablets)
BLACK CAVIDIOL MASK
FUCOIDAN HAIR TONIC
Gene 16 Whitening Factor
REBORNCELL CLEANSING
bmse000437
OHL O2
Anti-Chafe StickPro Series
ALLANTOIN [WHO-DD]
Calm and Heal Melting Balm
Miracle GYN (2 Tablets)
Miracle GYN (4 Tablets)
SCHEMBL3208
Cetaphil Soothing Gel Cream
GMDANSU Herbal Mask Sheet
Pelo Baum Hair Revitalizing
Rite Aid Advanced Scar Gel
Sheffield Advanced Scar Gel
Walgreens Advanced Scar Gel
BIOWHITE BEAUTY SERUM
DR DEEP AQUA WRINKLE
OZ TREEHandMade by Dorothy
Secret Gyno (10 Tablets)
Shelo NABEL D B T Cream
Oprea1_621175
Tamnamo Vital Hair Treatment
BSPBio_000003
BSPBio_002551
KBioGR_001271
KBioSS_001558
Miracle GYN (10 Tablets)
Shelo NABEL Jabon Baba Car
SISEUNDEUSI BLESS BODY
VetraCare Pet Liquid Bandage
Dr. Dog Skin Care for Dogs
Luxury Cell Performance Serum
Luxury Cell Performance Toner
M-Rose Seaweed Essence Serum
M-Rose Seaweed Hydrogel Mask
MLS002473300
Shelo NABEL Baba de Caracol
Well and Good Liquid Bandage
Allantoin, analytical standard
DivK1c_000281
SPECTRUM1500801
CVS Health Advanced Scar Gel
Macoma Senior Premium Cleanser
Queen Perfume Hair Conditioner
SPBio_000237
SPBio_001924
Cellpium vampire cleansing mask
Dermaheal Ultimatum PTx Sports
Lycoris RUBUS Whitening Fluid
BPBio1_000005
CHEMBL593429
Diabetic Wound Gel Professional
Hasol Revitalizing Scalp Ampoule
Inflammation OTCRadiation Relief
Luxury Cell Performance Emulsion
SD 101 [WHO-DD]
5-Ureidohydantoin;Glyoxyldiureide
ATOBOS BABY AQUA SOOTHING
HAIRJOY MSM SCALP ESSENCE
HMS500O03
HY-N0543R
KBio1_000281
KBio2_001558
KBio2_004126
KBio2_006694
KBio3_002051
REBORNCELL AQUA RICH SOFT
VET WORTHY LIQUID BANDAGE
Vital Fluid IV Nano Gold Serum
Allantoin, >=98.0% (N)
Parma Anus Skin Premium Cleanser
PLAGENTRA BABY BUBBLE WASH
Leaders Mediu Purifying Salt Pack
NINDS_000281
Urea,5-dioxo-4-imidazolidinyl)-
Dr Deep Brightening FacialEmulsion
HMS1568A05
HMS1921I10
HMS2092K16
HMS2095A05
HMS2268N08
HMS3712A05
HMS3885M08
LUMINANT UMBRELLA MASK PACK
Pharmakon1600-01500801
Fikia Marine Delight Soothing Mist
Shelo NABEL CACAO Skin Protectan
U-max Whitening Functional Essence
3CE FIXER AND MASCARA BLACK
3CE FIXER AND MASCARA BROWN
BCP31832
Blister Armour Anti-FrictionMission
component of Skin-balm (Salt/Mix)
HY-N0543
Lycoris rubus whitening moisturizing
M-Rose Seaweed Lifting Revitalizing
PHYTON THERAPY CLEANSING BAR
Ramosu The Witches Cream Pack Gold
Shelo NABEL Crema Baba de Caracol
UYB40251
2,5-Imidazolidinedione, 4-ureido-
Cellapy MGF Hydro Gel Intense Mask
Tox21_110395
Tox21_202087
Tox21_302912
BBL027508
CCG-39781
IASOBETIC Allantoin Skin Protectant
NSC757792
s3856
STL373778
BK Cell 2STEP AQUA TOKTOK MASK
REBORNCELL AQUA RICH PURE SKIN
AKOS000120642
AKOS016038547
Dr Young 2p Blemish Base SPF35 PA
Skin Barista Rice Bran Cleansing Foam
Tox21_110395_1
1ST2594
By Pharmicell Lab The Prestige Essence
Cetaphil Baby Soothe and Protect Cream
CS-7741
DB11100
FA01871
NSC-757792
SDCCGMLS-0066595.P001
IDI1_000281
USEPA/OPP Pesticide Code: 085701
Allantoin, p.a., 98.5-101.0%
IONTOPHORESISANTI AGING SOLUTION I
N-(2,5-Dioxo-4-imidazolidinyl)urea #
NCGC00094854-01
NCGC00094854-02
NCGC00094854-03
NCGC00094854-04
NCGC00094854-05
NCGC00094854-06
NCGC00094854-07
NCGC00094854-08
NCGC00256403-01
NCGC00259636-01
(RS)-(2,5-dioxoimidazolidin-4-yl)urea
AC-11040
AS-13865
NCI60_041675
Scar ReducerIntensive Herbal and Nutrient
DGH Advanced Formula Scar Skin Protectant
QYO QYO Tangerine Bright Moist Mask Pack
SBI-0051759.P002
Vital Fluid I Platinum Anti Wrinkle Serum
Leaders Mediu Pore Cleaning Carbonated Pack
NOBLESSE MANZ GROOMING SO CLEAN CARE
A0211
AB00052307
BIOXIDEA ELEMENT 48 NATURA GOLD MASK
HAIRFILL SCALP HAIR ESSENTIAL BOOSTER
LEADERS MEDIU CALMING PEPPERMINT PACK
NS00009152
Shelo NABEL Baba de Caracol Locion Corporal
Vital Fluid II EGF and FGF Whitening Serum
EN300-21043
SECRETIPSS SCALP HAIR ESSENTIAL BOOSTER
BIOXIDEA ELEMENT 48 NATURA DIAMOND MASK
C01551
D85069
HAIRFILL SCALP HAIR ESSENTIAL TONIC PLUS
Urea, (2,5-dioxo-4-imidazolidinyl)- (9CI)
AB00052307_11
BIOXIDEA MIRACLE 48 EXCELLENCE GOLD MASK
By Pharmicell Lab Luxury Cell Performance Serum
By Pharmicell Lab Luxury Cell Performance Toner
By Pharmicell Lab Moisturizing Face Toning Mist
Dr. Young 2P Pearl Brightening Balm SPF35 PA
Jabon Shelo Nabel Con Alantoina Baba de Caracol
By Pharmicell Lab Luxury Cell Performance Emulsion
Q409804
SECRETIPSS SCALP HAIR ESSENTIAL TONIC PLUS
BIOXIDEA MIRACLE 48 EXCELLENCE DIAMOND MASK
HYUNDAE MEDITECH BIO HAIR SOLU TION ERUA DO
ORIGINAL POWER WHITENING AND LINELESS AMPOULE
SkinCeuticals Advanced Scar Control Skin Protectant
SR-01000766252-2
SR-01000766252-3
SR-01000766252-4
BRD-A96407378-001-15-1
N-(2,5-dihydroxy-4h-imidazol-4-yl) carbamimidic acid
Z104486690
Allantoin, European Pharmacopoeia (EP) Reference Standard
NANOMIX NANO CLEANSkin Protectant Antibacterial Function
A999F0D6-0285-41D9-A6BA-B705987B663C
Allantoin, United States Pharmacopeia (USP) Reference Standard
BOTANETH PRONOXIN HAIR REGAINER FS2 ACTIVATOR 2-A 2-B
Allantoin, Pharmaceutical Secondary Standard; Certified Reference Material
SECRETIPSS SCALP HAIR ESSENTIAL BOOSTERINTENSE CARE FOR DAMAGED SCALPS AND HAIRS
202-592-8
5-Ureidohydantoin; Glyoxyldiureide; Glyoxylic diureide; Cordianine; Glyoxyldiureid; (2,5-Dioxo-4-imidazolidinyl)urea